HOME >> MEDICINE >> NEWS
Newer biomarkers add small improvement in cardiovascular risk prediction to established risk factors

Results of a long-term Framingham Heart Study investigation of multiple biomarkers for the prediction of first major cardiovascular events and death are reported in the December 21 issue of the New England Journal of Medicine (NEJM).

In the study, scientists followed 3209 participants in the Framingham Heart Study for 10 years and measured 10 of the most promising novel biomarkers for predicting the risk of cardiovascular disease (CVD). The newer biomarkers such as natriuretic peptides, C-reactive protein, fibrinogen, urinary albumin, and homocysteine were compared with established risk factors such as high blood pressure, diabetes, and high cholesterol. Measuring several biomarkers simultaneously, referred to as the "multimarker" approach, enabled the scientists to stratify risk. They found that persons with high multimarker scores had a risk of death four times as great and a risk of major cardiovascular events almost two times as great as persons with low multimarker scores. However, the use of multiple biomarkers added only moderately to the overall prediction of risk based on conventional risk factors.

"Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death," was funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Daniel Levy, M.D., Director of the Framingham Heart Study, is available to comment on the studys affirmation of the importance of traditional risk factors. He can also discuss the promise of new biomarkers --despite their modest enhancement over conventional risk factors-- in identifying individuals at high risk for cardiovascular events. In addition, Levy can comment on NHLBIs recently announced large-scale biomarker project, a proposed biomarker consortium to conduct research on novel CVD biomarkers and develop new diagnostic tests to identify individuals at high risk for CVD and its risk factors.


'"/>

Contact: NHLBI Communications Office
nhlbi_news@nhlbi.nih.gov
301-496-4236
NIH/National Heart, Lung, and Blood Institute
20-Dec-2006


Page: 1

Related medicine news :

1. Newer chemotherapies improve outcomes for some types of breast cancer
2. Newer form of cardiac imaging providing better look at heart
3. Newer diabetic meds cost more, but users have fewer hospital visits
4. Newer imaging techniques may lead to over-treatment
5. Scientists create dual-modality microbeads to improve identification of disease biomarkers
6. Ability of biomarkers to predict risk of heart disease, stroke appears limited
7. Researchers use statistical technique to find mix of biomarkers predicting mortality
8. New biomarkers for improving treatment of spondylarthritis
9. New microchip technology for medical imaging biomarkers of disease
10. Africa: International volunteer impact small, but significant
11. Nonsmall cell lung cancer -- chemotherapy before surgery appears better than surgery alone

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: