HOME >> MEDICINE >> NEWS
Nicotine exposure can increase motivation to respond for food weeks after the last exposure

New Haven, Conn.- A new study by Yale researchers shows that prior nicotine exposure in mice can increase their motivation to respond work for food, weeks after their last exposure to nicotine, a finding that runs counter to the popular belief that nicotine exposure curbs appetite.

The study, to be published in an upcoming issue of Psychopharmacology, also sheds new light on the role played by certain nicotinic acetylcholine receptors when it comes to the reinforcing aspects of nicotine.

The study provides insight into one of the most vexing issues relating to smoking cessation, one that discourages many people from attempting to quit smoking, the prospect of weight gain. "Although acute nicotine can act as an appetite suppressant, these data are the first to suggest that repeated exposure to nicotine has the opposite effect, that nicotine increases motivation for food for weeks following exposure to the drug," said Darlene Brunzell, associate research scientist in the Department of Psychiatry and first author of the study.

"This research suggests that when young people take up smoking to regulate their weight, this may be counterproductive in addition to being harmful to their health," said Stephanie O'Malley, professor of psychiatry and principal investigator for the Center for Nicotine & Tobacco Use Research at Yale. "More research is needed to determine how exactly that works, but this does show that there could be a connection between exposure to nicotine and subsequent weight gain in some individuals."

In addition, the study identifies which nicotinic receptors are involved in nicotine's control over cues. "We knew previously that cues play a critical role in nicotine and tobacco consumption in animals and humans," said Brunzell. "These studies show that Beta 2 nicotinic receptors are necessary for nicotine's ability to increase the control that cues have over behavior." said Dr. Darlene Brunzell, Ph.D., first
'"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
31-Aug-2005


Page: 1 2

Related medicine news :

1. Nicotine receptors on kidneys may speed kidney damage
2. Nicotine found to protect against Parkinsons-like brain damage
3. Childhood sun exposure may lower risk of MS
4. Risk of Parkinsons disease increases with pesticide exposure and head trauma
5. In utero exposure to smoking by mother can increase risk of ADHD
6. Agent protects cells from lethal effects of radiation even if given after exposure
7. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
8. Pre-exposure prophylaxis against HIV infection: Which drugs should be tested?
9. Childhood lead exposure linked to increased injuries as teens
10. Solvent exposure linked to birth defects in babies of male painters
11. Global view shows strong link between kidney cancer, sunlight exposure

Post Your Comments:
(Date:7/1/2015)... ... July 01, 2015 , ... ... new extraction plant for Linablue®, Spirulina-derived natural blue food coloring. Construction of the ... DIC Group’s U.S. Spirulina* production base, began in May 2014. After commissioning, commercial ...
(Date:7/1/2015)... ... July 01, 2015 , ... Renowned rhinoplasty surgeon and ... 2016 Dallas Rhinoplasty Symposium . Set for March 6th - 8th, the 2016 ... participants from the basic training and fundamentals of nasal surgery through the most modern ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... leaders Lora Posey (Manager, National Sales Training and Development) and Chuck Corso (Associate ... (LTEN) Conference in Phoenix, AZ. LTEN brings together learning and development professionals from ...
(Date:7/1/2015)... ... - (PRWEB) July 01, 2015 , ... Lisa Keys, ... virtual 5K on August 15-16th (MSG Keys’ birthday) in memory of her late husband ... decorated soldier and recipient of the Bronze Star Medal, died during a Special Forces ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... author Lisa Stolzenberg, a Professor in FIU’s School of International and Public Affairs. ... 17 years who participated in the National Survey on Drug Use and Health, ...
Breaking Medicine News(10 mins):Health News:DIC Strengthens Its Position as the Global Leader for Natural Blue Food Coloring 2Health News:DIC Strengthens Its Position as the Global Leader for Natural Blue Food Coloring 3Health News:Dr. Rod J. Rohrich Announces Dates for 2016 Dallas Rhinoplasty Symposium 2Health News:Dr. Rod J. Rohrich Announces Dates for 2016 Dallas Rhinoplasty Symposium 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 2Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 4Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 2Health News:Wife of Fallen Special Forces Soldier to Host Nationwide ‘Virtual 5K’ for Charity 3Health News:Researchers find that medical marijuana laws increase recreational marijuana use among juveniles 2
(Date:7/1/2015)... it is expanding its Baltimore -based clinical studies network and is recruiting ... patient populations.  Photo - http://photos.prnewswire.com/prnh/20150630/227303 ... ... ... "Continental hosts clinical studies for physicians across all ...
(Date:7/1/2015)... 2015  BioPharmX Corporation (NYSE MKT: BPMX) today announced ... of 3,636,364 shares of its common stock at a ... has granted the underwriters a 30-day option to purchase ... the public offering price. In addition, Korea ... has agreed to purchase 1,081,081 shares of common stock ...
(Date:7/1/2015)... ZURICH , July 1, 2015 ... reorganise its Executive Board. Mr. Gert Weber ... Medico Invest AG as Chief Executive Officer (CEO) ... starting July 1 st , 2015. Mr. Weber brings ... and technological industries and has filled various executive management ...
Breaking Medicine Technology:Continental Clinical Solutions CEO Saleh Stevens Eyes Growth 2Continental Clinical Solutions CEO Saleh Stevens Eyes Growth 3Continental Clinical Solutions CEO Saleh Stevens Eyes Growth 4BioPharmX Corporation Closes Underwritten Public Offering of Common Stock 2BioPharmX Corporation Closes Underwritten Public Offering of Common Stock 3Haselmeier Group Announces the Extension and Reorganization of its Executive Board 2
Cached News: