HOME >> MEDICINE >> NEWS
Nicotine exposure can increase motivation to respond for food weeks after the last exposure

New Haven, Conn.- A new study by Yale researchers shows that prior nicotine exposure in mice can increase their motivation to respond work for food, weeks after their last exposure to nicotine, a finding that runs counter to the popular belief that nicotine exposure curbs appetite.

The study, to be published in an upcoming issue of Psychopharmacology, also sheds new light on the role played by certain nicotinic acetylcholine receptors when it comes to the reinforcing aspects of nicotine.

The study provides insight into one of the most vexing issues relating to smoking cessation, one that discourages many people from attempting to quit smoking, the prospect of weight gain. "Although acute nicotine can act as an appetite suppressant, these data are the first to suggest that repeated exposure to nicotine has the opposite effect, that nicotine increases motivation for food for weeks following exposure to the drug," said Darlene Brunzell, associate research scientist in the Department of Psychiatry and first author of the study.

"This research suggests that when young people take up smoking to regulate their weight, this may be counterproductive in addition to being harmful to their health," said Stephanie O'Malley, professor of psychiatry and principal investigator for the Center for Nicotine & Tobacco Use Research at Yale. "More research is needed to determine how exactly that works, but this does show that there could be a connection between exposure to nicotine and subsequent weight gain in some individuals."

In addition, the study identifies which nicotinic receptors are involved in nicotine's control over cues. "We knew previously that cues play a critical role in nicotine and tobacco consumption in animals and humans," said Brunzell. "These studies show that Beta 2 nicotinic receptors are necessary for nicotine's ability to increase the control that cues have over behavior." said Dr. Darlene Brunzell, Ph.D., first
'"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
31-Aug-2005


Page: 1 2

Related medicine news :

1. Nicotine receptors on kidneys may speed kidney damage
2. Nicotine found to protect against Parkinsons-like brain damage
3. Childhood sun exposure may lower risk of MS
4. Risk of Parkinsons disease increases with pesticide exposure and head trauma
5. In utero exposure to smoking by mother can increase risk of ADHD
6. Agent protects cells from lethal effects of radiation even if given after exposure
7. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
8. Pre-exposure prophylaxis against HIV infection: Which drugs should be tested?
9. Childhood lead exposure linked to increased injuries as teens
10. Solvent exposure linked to birth defects in babies of male painters
11. Global view shows strong link between kidney cancer, sunlight exposure

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/7/2016)... ... 2016 , ... Augustine Insurance Agency, a locally owned and ... in the greater Dallas metropolitan area, is announcing a charity event that promises ... in 2009 by active police professionals in the Dallas region, the Dallas Fallen ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... Sharon Kleyne, ... Global Climate Change and Your Health on Voice of America, declared on her radio ... call attention to the fact that when these bullies attack leaders in corporate America, ...
(Date:12/7/2016)... , ... December 07, 2016 , ... ... 20 Marketing Campaign Winner in the Folio: Marketing Awards competition. Live From won ... year’s best in pioneering, inventive, and ultimately successful projects undertaken by the media ...
(Date:12/7/2016)... ... December 07, 2016 , ... Maureen McLaughlin, LA.c., a ... Medicine Associates of Connecticut (RMACT). McLaughlin brings nearly 20 years of experience with ... help patients realize their family building goals. Acupuncture helps fertility patients ...
(Date:12/7/2016)... ... (PRWEB) December 07, 2016 , ... Angioma Alliance ( http://www.angioma.org ... angiomas, was awarded a grant from the Julian Grace Foundation to increase its ... more people with cavernous angioma than anywhere in the world. Most share a ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... 6, 2016 Homozygous Familial Hypercholesterolemia ... Summary Global Markets Direct,s latest Pharmaceutical ... Hypercholesterolemia (HoFH) – Pipeline Review, H2 2016, ... Hypercholesterolemia (HoFH) (Metabolic Disorders) pipeline landscape. ... which is caused due to mutation from ...
(Date:12/6/2016)... Colo. , Dec. 6, 2016   ... of cartilage, cellular, bone, skin and soft-tissue allografts ... Meyer , Business Process Manager, for being named ... Malcolm Baldrige National Quality Award by the Commerce ... deepening the organization,s commitment to process excellence. The ...
(Date:12/6/2016)... 2016 Two new disaster drones delivered telemedical ... mass casualty event Tuesday at John Bell Airport in ... before an audience including Mississippi ... Security, Federal Law Enforcement Agencies, and the United Nations. ... (Health Integrated Rescue Operations), was developed by Italo ...
Breaking Medicine Technology:
Cached News: