HOME >> MEDICINE >> NEWS
Nicotine exposure can increase motivation to respond for food weeks after the last exposure

New Haven, Conn.- A new study by Yale researchers shows that prior nicotine exposure in mice can increase their motivation to respond work for food, weeks after their last exposure to nicotine, a finding that runs counter to the popular belief that nicotine exposure curbs appetite.

The study, to be published in an upcoming issue of Psychopharmacology, also sheds new light on the role played by certain nicotinic acetylcholine receptors when it comes to the reinforcing aspects of nicotine.

The study provides insight into one of the most vexing issues relating to smoking cessation, one that discourages many people from attempting to quit smoking, the prospect of weight gain. "Although acute nicotine can act as an appetite suppressant, these data are the first to suggest that repeated exposure to nicotine has the opposite effect, that nicotine increases motivation for food for weeks following exposure to the drug," said Darlene Brunzell, associate research scientist in the Department of Psychiatry and first author of the study.

"This research suggests that when young people take up smoking to regulate their weight, this may be counterproductive in addition to being harmful to their health," said Stephanie O'Malley, professor of psychiatry and principal investigator for the Center for Nicotine & Tobacco Use Research at Yale. "More research is needed to determine how exactly that works, but this does show that there could be a connection between exposure to nicotine and subsequent weight gain in some individuals."

In addition, the study identifies which nicotinic receptors are involved in nicotine's control over cues. "We knew previously that cues play a critical role in nicotine and tobacco consumption in animals and humans," said Brunzell. "These studies show that Beta 2 nicotinic receptors are necessary for nicotine's ability to increase the control that cues have over behavior." said Dr. Darlene Brunzell, Ph.D., first
'"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
31-Aug-2005


Page: 1 2

Related medicine news :

1. Nicotine receptors on kidneys may speed kidney damage
2. Nicotine found to protect against Parkinsons-like brain damage
3. Childhood sun exposure may lower risk of MS
4. Risk of Parkinsons disease increases with pesticide exposure and head trauma
5. In utero exposure to smoking by mother can increase risk of ADHD
6. Agent protects cells from lethal effects of radiation even if given after exposure
7. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
8. Pre-exposure prophylaxis against HIV infection: Which drugs should be tested?
9. Childhood lead exposure linked to increased injuries as teens
10. Solvent exposure linked to birth defects in babies of male painters
11. Global view shows strong link between kidney cancer, sunlight exposure

Post Your Comments:
(Date:3/3/2015)... 2015 The biggest name in indoor ... the world’s first fully integrated air quality platform that ... an air purifier to remove dust, pollen and hazardous ... control, via phone, tablet or computer. , Sweden’s Blueair, ... countries worldwide, will unveil its Internet-enabled air sensor together ...
(Date:3/3/2015)... UK (PRWEB) March 03, 2015 The ... growth of the augmentation market. The wearable augmentation sector ... terms of size in the upcoming years. , ... market owing to a big number of new products ... North American region, high technological advancements as well as ...
(Date:3/3/2015)... 2015 Daylight Savings Time may lead to ... has tips for parents. , Parents and their children may ... a.m. when they set their clocks forward one hour for ... day -- one hour earlier -- you will have already ... start thinking about “sleep hygiene” for their kids and teens ...
(Date:3/3/2015)... Sunday, March 1, through Saturday, March 7, ... of year, every region of the country is at risk ... Amica Insurance is sharing the following tips from the ... keep you safe in the event of severe weather: , ... clothing frequently to prevent loss of body heat. Wear warm, ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 -- vRad ( Virtual Radiologic ... today announced that Arlene Sussman, MD, a highly regarded ... live webinar to explore how telemedicine best practices allow ... services for women virtually anywhere. Click here ... Line” on March 4, 2015 at 1:00 pm CT. ...
Breaking Medicine News(10 mins):Health News:Smart sensor and air purifier interconnect to track and trap dust, pollen and dangerous particles in home and workplace air 2Health News:Human Augmentation Market to Pose 43.5% CAGR Through 2020, States MarketsandMarkets in its New Research Study Now Available at MarketPublishers.com 2Health News:Don’t Let Daylight Savings Disrupt Your Child’s Sleep 2Health News:Amica Insurance Has Tips for National Severe Weather Preparedness Week 2Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 2Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 3Health News:Latest vRad Webinar: Building World-Class Breast Imaging Services Virtually Anywhere with Telemedicine Best Practices 4
(Date:3/3/2015)... 3, 2015  Michigan brothers Dominique Larkin , 23, ... right ventricular dysplasia, or ARVD, a disease that causes irregular ... among young athletes. In 2007, doctors discovered the ... They later tested Dominique and found his "condition was just ... 2015 story in The Ann Arbor News , part ...
(Date:3/3/2015)... 2015 Research and Markets ( ... "Global Ultrasound Equipment Market 2015-2019" report ... The Global Ultrasound Equipment market to grow at ... Ultrasound equipment are used to examine ... extensively used by cardiologists, radiologists, surgeons, obstetricians, and ...
(Date:3/3/2015)... Pa. , March 3, 2015   ... laboratory products, services and solutions, announced today the ... Biolabs®, Inc. (NEB®). This agreement allows VWR increased ... technical support in the U.S. and Puerto Rico.  ... NEB,s products through VWR,s e-business platform, sales organization, ...
Breaking Medicine Technology:Younger of 2 Brothers on the SynCardia Total Artificial Heart Gets a Donor Heart Transplant 2Younger of 2 Brothers on the SynCardia Total Artificial Heart Gets a Donor Heart Transplant 3Global Ultrasound Equipment Market 2015-2019: Rise in Number of MI Diagnostic Procedures with GE Healthcare, Phillips Healthcare, Siemens Healthcare & Toshiba Medical Systems Dominating 2VWR Announces Expansion of Distribution Agreement with New England Biolabs 2
Cached News: