HOME >> MEDICINE >> NEWS
Nicotine exposure can increase motivation to respond for food weeks after the last exposure

New Haven, Conn.- A new study by Yale researchers shows that prior nicotine exposure in mice can increase their motivation to respond work for food, weeks after their last exposure to nicotine, a finding that runs counter to the popular belief that nicotine exposure curbs appetite.

The study, to be published in an upcoming issue of Psychopharmacology, also sheds new light on the role played by certain nicotinic acetylcholine receptors when it comes to the reinforcing aspects of nicotine.

The study provides insight into one of the most vexing issues relating to smoking cessation, one that discourages many people from attempting to quit smoking, the prospect of weight gain. "Although acute nicotine can act as an appetite suppressant, these data are the first to suggest that repeated exposure to nicotine has the opposite effect, that nicotine increases motivation for food for weeks following exposure to the drug," said Darlene Brunzell, associate research scientist in the Department of Psychiatry and first author of the study.

"This research suggests that when young people take up smoking to regulate their weight, this may be counterproductive in addition to being harmful to their health," said Stephanie O'Malley, professor of psychiatry and principal investigator for the Center for Nicotine & Tobacco Use Research at Yale. "More research is needed to determine how exactly that works, but this does show that there could be a connection between exposure to nicotine and subsequent weight gain in some individuals."

In addition, the study identifies which nicotinic receptors are involved in nicotine's control over cues. "We knew previously that cues play a critical role in nicotine and tobacco consumption in animals and humans," said Brunzell. "These studies show that Beta 2 nicotinic receptors are necessary for nicotine's ability to increase the control that cues have over behavior." said Dr. Darlene Brunzell, Ph.D., first
'"/>

Contact: Jacqueline Weaver
jacqueline.weaver@yale.edu
203-432-8555
Yale University
31-Aug-2005


Page: 1 2

Related medicine news :

1. Nicotine receptors on kidneys may speed kidney damage
2. Nicotine found to protect against Parkinsons-like brain damage
3. Childhood sun exposure may lower risk of MS
4. Risk of Parkinsons disease increases with pesticide exposure and head trauma
5. In utero exposure to smoking by mother can increase risk of ADHD
6. Agent protects cells from lethal effects of radiation even if given after exposure
7. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
8. Pre-exposure prophylaxis against HIV infection: Which drugs should be tested?
9. Childhood lead exposure linked to increased injuries as teens
10. Solvent exposure linked to birth defects in babies of male painters
11. Global view shows strong link between kidney cancer, sunlight exposure

Post Your Comments:
(Date:10/31/2014)... Missouri (PRWEB) October 31, 2014 With ... school, one Midwest optometrist feels they may overlook one ... to affect areas like concentration, school performance and even ... be too brief to identify progressive vision problems, and ... Joseph, Mo., announces a new initiative: The Awesome Eyes ...
(Date:10/31/2014)... News) -- Sleep apnea may make it hard for you ... car or left your house keys, a small study suggests. ... that this ability -- called spatial memory -- was impaired ... when other stages of sleep weren,t affected. REM sleep is ... "We,ve shown for the first time that sleep apnea, ...
(Date:10/31/2014)... that either they or a family member have experienced ... issue of The Gerontological Society of America,s Public ... goes on to show that Americans strongly support holding ... health care wishes. , This PP&AR , titled ... 12 articles that present new ways of understanding the ...
(Date:10/31/2014)... North Shore Eye Care today announced ... Island and the addition of leading ophthalmologist, William S. ... North Shore Eye Care Medical Director, Jeffrey Martin, MD. ... the Department of Ophthalmology of Winthrop-University Hospital and has ... for more than 30 years. He has been named ...
(Date:10/31/2014)... 31, 2014 FindSurrogateMother.com conveys ... gifts of life — building a family through surrogacy. ... mothers and donors with hopeful intended parents in turn ... , It’s a collective aptitude of surrogate mothers, intended ... and fertility clinics that help provide these connections — ...
Breaking Medicine News(10 mins):Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 2Health News:New School Vision Initiative Announced by Dr. Rosenak’s Optical Options; Program Aims to Help Recognize Unseen Vision Problems That Impact School Success 3Health News:Sleep Apnea May Steal Some of Your Memory: Study 2Health News:Advance directives can benefit patients, families, and health care system 2Health News:William Kasper, MD Garden City Ophthalmologist, Joins Medical Staff at North Shore Eye Care 2Health News:William Kasper, MD Garden City Ophthalmologist, Joins Medical Staff at North Shore Eye Care 3Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 2Health News:Over 800 New Surrogate Mother Members at FindSurrogateMother.com Helping Create Pathways to Parenthood 3
(Date:10/31/2014)... 3, 2014 British Journal ... BPH to discuss "male orgasmic dysfunction" with their doctor ... treat prostate symptoms while preserving sexual function   ... publication of a paper in the British Journal of ... prostate to discuss with their doctors the likely impact ...
(Date:10/31/2014)... BARCELONA , October 31, 2014 ... two Australian patents of B. Braun Melsungen AG (B. Braun) ... safety IV catheters manufactured by Poly Medicure Ltd ... Australia proceeding number VID 463 of 2013 ... In the detailed judgment, Multigate was found to have infringed ...
(Date:10/31/2014)... 30, 2014 Migranade, Inc. announced today the ... to the 36 million U.S. migraine sufferers November, 2014. ... targets the actual cause of migraines and not just ... not the source Migranade is assured to be a ... Relief is available at http://www.migranade.com and will ...
Breaking Medicine Technology:Sexual Dysfunction No Longer Inevitable When Treating Enlarged Prostate 2B. Braun Wins Patent Disputes Against Poly Medicure Ltd's Australian Distributor Multigate Medical Devices Pty. Ltd. and Spanish Distributor Dextromédica S. L. 2Game Changing Migraine Medication To Be Available November 2014 2
Cached News: