HOME >> MEDICINE >> NEWS
Nicotine found to protect against Parkinson's-like brain damage

New research suggests that nicotine treatment protects against the same type of brain damage that occurs in Parkinson's disease. The research was conducted in laboratory animals treated with MPTP, an agent that produces a gradual loss of brain function characteristic of Parkinson's. Experimental animals receiving chronic administration of nicotine over a period of six months had 25 percent less damage from the MPTP treatment than those not receiving nicotine.

This protective effect may explain the lower incidence of Parkinson's disease among smokers. The results also suggest that nicotine may be useful as a potential therapy in the treatment of early-stage Parkinson's patients.

The five-year study was conducted by researchers at The Parkinson's Institute, an independent, non-profit research institute located in Sunnyvale, California. The study results are published in an on-line early release in the Journal of Neurochemistry (doi:10.1111/j.1471-4159.2006.04078.x)

Parkinson's disease is a progressive, neurodegenerative disease caused by the death of small clusters of cells in the midbrain. The gradual loss of these cells results in reduction of a critical transmitter called dopamine, the chemical messenger responsible for normal movement.

"While we would never recommend that people smoke, these results suggest that nicotine promotes the survival of dopamine-producing cells in animals with no overt Parkinson's symptoms," said David A. Schwartz, M.D., director of the National Institute of Environmental Health Sciences, the federal agency that provided funding for the study. "These findings also have implications for its use in slowing the progression of Parkinson's." '"/>

Contact: Kellie A Hayes
khayes@thepi.org
408-542-5663
The Parkinson's Institute
7-Aug-2006


Page: 1 2 3

Related medicine news :

1. Nicotine receptors on kidneys may speed kidney damage
2. Nicotine exposure can increase motivation to respond for food weeks after the last exposure
3. OFTs value-based pricing scheme is well-founded, but could increase overall NHS drug spend
4. Certain combination therapy found more effective for treating malaria in African children
5. Antifolate therapies found effective against certain type of malaria
6. High-quality child care for poor children found to offset the risk of later depression
7. No link found between autism and celiac disease
8. Correlation between bile duct obstruction and ductal cancer found
9. The root of dyscalculia found
10. Link found between teens stress levels and acne severity
11. CRP liver protein induces hypertension, UT Southwestern researchers have found

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/19/2020)... ... 19, 2020 , ... As confirmed cases of COVID-19 rapidly increase in the ... a global humanitarian organization, Project HOPE’s mandate is always to respond where the need ... Torbay, President and CEO of Project HOPE. “We will be supporting America’s health workers ...
(Date:3/19/2020)... ... March 20, 2020 , ... With ICH E8(R1) set to ... look different than they do today. Be ready to implement the new guidelines. ... shows readers how to leverage the revised guidelines’ quality-by-design approaches, expanded study designs and ...
(Date:3/15/2020)... ... March 13, 2020 , ... 4 out of 5 Americans ... the spread of coronavirus (COVID-19) in other countries. , Peter Yeo, President of the ... not optional—it’s an imperative. No country, including the U.S., can battle a pandemic on ...
(Date:3/15/2020)... Idaho (PRWEB) , ... March ... ... uncertainty and rising levels of confusing information surrounding the Coronavirus (COVID-19) pandemic, ... bear on the health concerns of businesses and employees. HouseCheck has launched ...
(Date:3/13/2020)... ... March 13, 2020 , ... ... United States. To promote the safety, health, and general well-being of our learners ... activities and, as of Monday, March 16, 2020, will shift to online synchronous ...
Breaking Medicine News(10 mins):
(Date:3/16/2020)... ... 16, 2020 , ... In the wake of the COVID-19 pandemic, Curogram ... is ramping efforts to help the containment of the global disease with its virtual ... management or EMR system. , “Our goal is to minimize exposure and maximize ...
(Date:3/16/2020)... ... March 16, 2020 , ... ... education platform, with content available from numerous organizations. Docola enables healthcare providers ... support patients before, after, or between face-to-face visits or on telemedicine appointments. ...
(Date:3/16/2020)... ... , ... In response to the COVID-19 pandemic, many companies are sending ... As of March 15, public schools across at least twenty-nine states have closed, with ... their children are also present. To help working parents adjust to these new and ...
Breaking Medicine Technology:
Cached News: