Not enough is known about treating malaria in pregnancy, researchers say

Few studies compare the effects of different drug regimes in pregnant women, and many of the best studies were conducted in Southeast Asia, where malaria transmission rates are low, says researcher Lois Orton of the University of York in England.

"Reliable research about the benefits and harms of treatments for malaria in pregnant women is scarce," Orton says.

The review appears in the July issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

In one of the studies analyzed by Orton and colleagues, a combination of the drugs artesunate and mefloquine was slightly better than the drug quinine at clearing malaria parasites from the bloodstream and reducing fever in pregnant women.

The risk of treatment failure was 9 percent less in the group receiving the combination drug regime, compared to treatment failure rates in the quinine group, the researchers found. The study included 106 women in Thailand.

The researchers reviewed six studies of antimalarial drugs in pregnant women in Southeast Asia and Africa. All of the women had uncomplicated malaria, meaning that they were ill and infected with the malaria parasite but not at immediate risk of dying from the disease. The studies included 513 women in their second or third trimester of pregnancy.

The studies tested a variety of antimalarial drugs, which complicated the reviewers' task of determining if any of the drug regimes should be recommended, according to Orton.

"As trials were all rather small and varied in the treatments evaluated, it is not surprising that this review was unable to demonstrate any clear direction for policy," Orton says.

One of the surprising findings of the study, according to the reviewers

Contact: Lois Orton
Center for the Advancement of Health

Page: 1 2

Related medicine news :

1. Wheres the beef? Not enough of it is on elders plates, muscle-metabolism study suggests
2. Inhaled steroids may not be enough for some children with asthma
3. Americans still not eating enough fruits and vegetables, according to 2 recent studies
4. Walking not enough for significant exercise benefits
5. Examination not sensitive enough to detect breech babies
6. Abstinence messages not enough for HIV prevention in Zambia
7. Menopausal women dont get enough guidance on treatment options, Stanford survey shows
8. UK plans for pandemic flu dont go far enough
9. Medical experts: US unlikely to have enough vaccines to stop avian flu
10. No-smoking rules not common enough for asthmatic children
11. Use of proven heart medicines improves, but not enough

Post Your Comments:

(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... awareness about the dangers associated with chronic pain and the benefits of holistic treatments, ... for individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the placement ... Vice President of North American Capital Sales at HTG Molecular . ... in the commercialization of the HTG EdgeSeq system and associated reagents in North America. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
Breaking Medicine Technology:
Cached News: