HOME >> MEDICINE >> NEWS
Novartis MS drug shows promising results

Basel, October 1, 2005 Data from the extension of a Phase II study to 12 months confirm the significant effects of FTY720, a novel oral medication, for the treatment of patients with relapsing multiple sclerosis (MS).

The data, presented at the ECTRIMS/ACTRIMS meeting in Thessalonica, Greece, showed that both patient groups taking FTY720 (1.25 mg and 5 mg) who had experienced a reduction in their annualized relapse rate of more than 50% during the first six months of the study compared to placebo maintained this low relapse rate during the subsequent six-month extension.

In patients who switched from placebo to either the 1.25 mg or 5 mg dosing of FTY720 after six months, the annualized relapse rate was reduced by at least 70% during the second six-month study phase compared to the first six months on placebo.

More than 80% of patients who received FTY720 for up to 12 months were free from lesions showing active inflammation on magnetic resonance imaging (MRI) at month twelve irrespective of their FTY720 treatment dose (1.25 mg or 5 mg).

"We are excited by these full-year study results confirming the significant effect of oral FTY720 on reducing both clinical relapses and inflammatory disease activity that we first saw during the six-month placebo-controlled phase of the study," said chief investigator Professor Ludwig Kappos, MD, Department of Neurology at the University Hospital in Basel, Switzerland, "We hope that the magnitude of benefits shown in Phase II will be confirmed in the larger scale Phase III study program expected to be launched soon." Based on the positive Phase II study results, Novartis is in discussions with regulatory authorities about the FTY720 Phase III program, which is expected to be launched by the end of 2005.

Over two million people worldwide are estimated to suffer from multiple sclerosis, which is the leading cause of neurological disability in young adults. MS is the most common ch
'"/>

Contact: Eva Reynolds
eva@reynoldsmackenzie.com
44-207-031-4361
Reynolds-MacKenzie
1-Oct-2005


Page: 1 2 3

Related medicine news :

1. BIDMC investigator receives Novartis Award in Diabetes
2. American Urological Association honors Novartis Pharmaceuticals with annual health science award
3. New study shows promise in reducing surgical risks associated with surgical bleeding
4. Most seniors now have drug coverage, U-M study shows
5. Wireless technology shows promise in diagnosing pediatric intestinal disease
6. Study shows radiofrequency ablation highly effective in treating kidney tumors
7. Method shows promise for early detection of pancreatic cancer
8. Organic farming can feed the world, U-M study shows
9. New study shows Rescue Remedy is an effective all-natural stress, anxiety reliever
10. Borderline personality disorder shows improvements with intensive psychotherapy
11. New drug shows promise in treatment of advanced thyroid cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/16/2019)... , ... August 16, 2019 , ... ... its annual Inc. 5000 list, the most prestigious ranking of the nation’s fastest-growing ... within the American economy’s most dynamic segment—its independent small businesses. Microsoft, Dell, Domino’s ...
(Date:8/16/2019)... ... August 16, 2019 , ... Dr. ... joined the esteemed Haute Beauty Network. , The Haute Beauty Network, well known ... Dr. Arnaoutakis as a hair restoration expert and our newest addition to the ...
(Date:8/15/2019)... ... 2019 , ... Heritage Woods of Rockford Administrator Jaclyn O’Keefe has been named ... award is part of the NCAL Awards Program, which recognizes exemplary assisted living caregivers. ... this year’s recipients is that they all go out of their way to ensure ...
(Date:8/14/2019)... ... ... New Hampshire-based Vera Roasting Company , makers of the only CBD coffee ... CBD-infused coffees with the release of a new higher-dosage organic Wellness Blend Coffee ... excited to expand our CBD-infused product lines to include a more potent CBD coffee ...
(Date:8/14/2019)... ... August 14, 2019 , ... Today, consumers are taking a harder look at ... physical body, emotions and energy levels. The trick is finding food and beverages that ... That’s why founder Chris Harper created Chase – a delicious, guilt free ...
Breaking Medicine News(10 mins):
(Date:8/16/2019)... ... 2019 , ... The American Academy of Emergency Medicine Physician ... as a member group. , SBEP is a longstanding democratic group that has ... out the AAEM-PG for administrative and practice management support that will help preserve ...
(Date:8/16/2019)... ... August 16, 2019 , ... Gainesville Dental Group , ... family dental practice that serves the Gainesville community with an extensive menu of ... and restorative dental care. The well-established practice is led by a team of ...
(Date:8/16/2019)... Mass. (PRWEB) , ... August 16, 2019 , ... ... and time to prepare the kids for returning to the classroom. The ... pediculosis so these students can join their friends free of lice and their ...
Breaking Medicine Technology:
Cached News: