Novel treatments may help alleviate constipation, IBS in women

rostone or placebo for 12 weeks and asked to rate their IBS symptoms. To be considered a monthly responder, patients had to report moderate relief four out of four weeks or significant relief two out of four weeks. Overall responders were defined as those who had been monthly responders two out of three months.

"The lubiprostone study demonstrates the continuing need for new and emerging therapies for IBS, especially for women," said Douglas A. Drossman, M.D., Co-Director, University of North Carolina Center for Functional Gastrointestinal and Motility Disorders in Chapel Hill, N.C., and lead author of the study. "We believe more research needs to be done to better determine lubiprostone's benefits and tolerability, but this study suggests people suffering from IBS and constipation may soon have another option for relief."

Dr. Drossman will present this study on Tuesday, May 22, at 11:45 a.m. in Room 151.

Effects of Novel, First-in-Class Guanylate Cyclase-C Activator, Linaclotide Acetate (MD-1100), on Gastrointestinal and Colonic Transit and Bowel Habits in Patients with Constipation-Predominant Irritable Bowel Syndrome (C-IBS) (Abstract #532)

Researchers are continually looking for unique pathways to treat digestive diseases, such as constipation and irritable bowel syndrome. Linaclotide is a novel therapy that works on a transmembrane protein in the lining of the gut called guanylate cyclase-C (GC-C). Specific gut hormones utilize GC-C to regulate intestinal fluid secretion. Linaclotide is unique in that it exerts its effect locally in the intestine while having minimal systemic exposure.

Thirty-six women suffering from IBS with constipation (IBS-C) were examined in a double-blind, placebo-controlled study, which consisted of a five-day baseline and a five-day treatment period. The endpoints were gastrointestinal transit and bowel function. Patients who received linaclotide experienced a significant

Contact: Aimee Frank
American Gastroenterological Association

Page: 1 2 3 4

Related medicine news :

1. Novel candidate biomarker for heart failure also strongly predicts risk of death
2. Novel catheter technique successfully patches holes in the heart
3. Novel anti-oxidant and anti-inflammatory agent shows effectiveness on key endpoints in trial
4. Novel Ames Lab composite may replace depleted uranium
5. Novel computed imaging technique uses blurry images to enhance view
6. Novel brain areas associated with the recognition of gender, ethnicity and the identity of faces
7. Novel program enhances dementia caregivers quality of life
8. Novel gene therapy may lead to cure in hemophilia A patients
9. Novel therapy combinations gain ground in treating hepatitis
10. Novel stem cell technology leads to better spinal cord repair
11. Novel virus entry mechanism could lead to new drugs against poxviruses

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: