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OHSU Cancer Institute, VA researchers find way to identify which men need a second biopsy

imilar to normal prostate tissue and the cancer is less likely to spread; a high Gleason score means the cancer tissue is very different from normal tissue and the tumor is more likely to spread. A high grade of cancer results in a higher PSA. Garzotto also stresses the size of the prostate has to be taken into account when measuring PSA.

"What we worry about is which men may have high-grade cancer. Now we can prescribe a second biopsy for a few months later. We know that this is a judicious use for a biopsy," Garzotto said. Besides identifying which men may have a deadly form of prostate cancer this new finding could also reduce the rate of overtreatment, unnecessary biopsies and overdiagnosis.

Prostate biopsies can cause patient anxiety, pain, bleeding and infection, and can lead to a significant increase in medical and non-medical costs to health care systems and patients.

This study is particularly meaningful because of the large sample size of patient cases, and it is longitudinal, which means researchers were able to study the patients for many years.


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Contact: Christine Decker
deckerch@ohsu.edu
503-494-8231
Oregon Health & Science University
2-Jun-2007


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