HOME >> MEDICINE >> NEWS
OHSU researchers discover possible HIV therapy in an animal study

PORTLAND, Ore. Researchers have published a new study this week suggesting an important component of the immune system damaged by AIDS can possibly be replaced. Specifically, researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University (OHSU) have been able to promote T-cell regeneration in a study involving rhesus macaque monkeys. The research is printed in the current edition of the Journal of Clinical Investigation.

As previous research has demonstrated, HIV attacks the host's immune system, including an important category of T cells critical for fighting infection called CD4+ T cells. The virus specifically destroys those CD4+ T cells that reside in the tissues of the body like the intestine and lung that interface with the outside environment. As HIV replicates in the human body, the tissue levels of CD4+ T cells are killed and, when the number of these cells drop below a certain level, a patient develops AIDS. At this point, the patient's immune system is weakened enough to allow infections caused by bacteria, viruses, fungi and parasites that are normally held at bay by a healthy human body. The infected body's inability to fight off these "intruders," leads to death.

"To learn more about HIV, its impacts and possible treatments, we study simian immunodeficiency virus (SIV), a close relative of HIV that infects and causes AIDS in nonhuman primates," explained the study's lead author Louis Picker, M.D. Picker serves as director of the VGTI's vaccine program and associate director of the VGTI. He is also a professor of pathology, and molecular microbiology and immunology in the OHSU School of Medicine; and director of the Division of Pathobiology and Immunology at the OHSU Oregon National Primate Research Center.

"What we were able to discover using SIV-infected monkeys was that a certain naturally occurring protein called interleukin-15 (IL-15) caused a dramatic restoration of tissue CD4+ T cel
'"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
8-Jun-2006


Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
3. Penn researchers discover novel pathway for increasing good cholesterol
4. Theory of facial aging gets a facelift from UT Southwestern researchers
5. UIC researchers to develop new drugs to fight bioterrorism
6. UQ researchers discover some of the oldest forms of life
7. U of M researchers discover new method to combat HIV
8. U of M researchers assess effectiveness of computerized physician order entry system
9. Nepalese researchers identify cost-effective treatment for drug-resistant typhoid
10. Physician-researchers often less successful in obtaining NIH funding
11. UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: OHSU researchers discover possible HIV therapy animal study

(Date:10/30/2014)... Burlington, NC (PRWEB) October 30, 2014 ... life, commercial, and health insurance plans for North Carolina ... its satellite office in Burlington’s Holly Hill Mall. The ... 15, with agents already helping customers through all facets ... policy purchase. , Allred Insurance spokesman Scott Allred couldn’t ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Radio listeners ... raising questions about the impact of traditional radio commercials ... method most likely to influence a purchasing decision. , ... of 525 consumers conducted by radio marketing company CRN ... categories, isolating the results of respondents who indicated they ...
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician and ... OB GYN in Melrose Park, IL and ... important information about each of the care services and practice ... in English and Spanish. The navigation of the website ... website provide Dr. Furlin’s patients with important information regarding his ...
(Date:10/30/2014)... The human brain is often overlooked ... to help maintain better mental health, according to Dr. ... Lose Your Memory in 100 Ways’ for just that ... conflicting attitudes to help keep the reader constantly thinking. ... must decipher the hidden logic within. , “If you ...
(Date:10/30/2014)... (HealthDay News) -- Scientists who used stem cells to ... breakthrough could provide a new way to learn more ... The team used human pluripotent stem cells -- which ... -- to grow the functional miniature stomachs, to study ... cause of ulcers and stomach cancer. The miniature ...
Breaking Medicine News(10 mins):Health News:Allred Insurance Satellite Office Grand Opening 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 2Health News:CRN Research On Radio Messaging Effectiveness Now Available In Four Specific Product Categories 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:‘Dementia Express’ Offers Contradictory and Sometimes Reverse Thinking, All to Keep its Reader on Their Toes With an Active Mind. 2
(Date:10/30/2014)... 2014 WuXi PharmaTech (Cayman) Inc. (NYSE: ... platform company serving the pharmaceutical, biotechnology, and medical device ... and the United States , today ... Tel Aviv area of Israel.  ... broad platform of integrated R&D services to local customers. ...
(Date:10/30/2014)... Boston Scientific Corporation (NYSE: BSX ... Suisse Annual Healthcare Conference on Tuesday, November 11, 2014 ... Brennan , executive vice president and chief financial officer, ... approximately 8:00 a.m. PT followed by a question and ... presentation and question and answer session will be available ...
(Date:10/30/2014)... , Oct. 30, 2014   ViaDerma, Inc. ... to bringing new products to market, has recently ... TetraStem. TetraStem is a topical liquid tetracycline-based antibiotic ... that can convert oral medication active ingredients into ... a first aid antibiotic to help prevent skin ...
Breaking Medicine Technology:WuXi AppTec Launches Representative Office in Israel, Forms Strategic Collaboration with Pontifax 2Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 2ViaDerma, Inc. Lead Product TetraStem Shown Effective in Fighting Staph Infections including MRSA 3
Cached News: