HOME >> MEDICINE >> NEWS
OHSU researchers discover possible HIV therapy in an animal study

PORTLAND, Ore. Researchers have published a new study this week suggesting an important component of the immune system damaged by AIDS can possibly be replaced. Specifically, researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University (OHSU) have been able to promote T-cell regeneration in a study involving rhesus macaque monkeys. The research is printed in the current edition of the Journal of Clinical Investigation.

As previous research has demonstrated, HIV attacks the host's immune system, including an important category of T cells critical for fighting infection called CD4+ T cells. The virus specifically destroys those CD4+ T cells that reside in the tissues of the body like the intestine and lung that interface with the outside environment. As HIV replicates in the human body, the tissue levels of CD4+ T cells are killed and, when the number of these cells drop below a certain level, a patient develops AIDS. At this point, the patient's immune system is weakened enough to allow infections caused by bacteria, viruses, fungi and parasites that are normally held at bay by a healthy human body. The infected body's inability to fight off these "intruders," leads to death.

"To learn more about HIV, its impacts and possible treatments, we study simian immunodeficiency virus (SIV), a close relative of HIV that infects and causes AIDS in nonhuman primates," explained the study's lead author Louis Picker, M.D. Picker serves as director of the VGTI's vaccine program and associate director of the VGTI. He is also a professor of pathology, and molecular microbiology and immunology in the OHSU School of Medicine; and director of the Division of Pathobiology and Immunology at the OHSU Oregon National Primate Research Center.

"What we were able to discover using SIV-infected monkeys was that a certain naturally occurring protein called interleukin-15 (IL-15) caused a dramatic restoration of tissue CD4+ T cel
'"/>

Contact: Jim Newman
newmanj@ohsu.edu
503-494-8231
Oregon Health & Science University
8-Jun-2006


Page: 1 2

Related medicine news :

1. Stanford researchers find culprit in aging muscles that heal poorly
2. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
3. Penn researchers discover novel pathway for increasing good cholesterol
4. Theory of facial aging gets a facelift from UT Southwestern researchers
5. UIC researchers to develop new drugs to fight bioterrorism
6. UQ researchers discover some of the oldest forms of life
7. U of M researchers discover new method to combat HIV
8. U of M researchers assess effectiveness of computerized physician order entry system
9. Nepalese researchers identify cost-effective treatment for drug-resistant typhoid
10. Physician-researchers often less successful in obtaining NIH funding
11. UCLA researchers develop new nanomaterials to deliver anti-cancer drugs to cells

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: OHSU researchers discover possible HIV therapy animal study

(Date:4/18/2015)... April 18, 2015 Carinsurancesavings.biz has released ... plans are cheaper during Spring. , Spring ... insurance plan. Drivers should make sure they compare the ... vehicles. Clients can learn more about Spring car insurance ... , Auto insurance quotes are becoming more and more ...
(Date:4/18/2015)... PA (PRWEB) April 18, 2015 "I ... evacuation stretchers in healthcare facilities," said an inventor from ... alternative storage system." , He developed the Slyde Door ... doors used in healthcare facilities. It provides convenient storage ... there are more stretchers available for patients. , ...
(Date:4/18/2015)... April 18, 2015 Review of Ophthalmology ... a ‘Strategies for Success’ program for cataract surgeons attending ... in San Diego, where eye surgeon Jeffrey L. Martin, ... invitation-only event. Dr. Martin is the Managing Partner of ... Ophthalmology chose Dr. Martin to lead this year’s discussion ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 Lowcostcarinsuranceprice.com has ... theft rates have on auto insurance prices . ... high rates of vehicle theft may have to pay ... Some liability auto insurance policies can also offer protection ... can now be compared online on a single website: ...
(Date:4/18/2015)... NC (PRWEB) April 18, 2015 Patients ... risk of developing mesothelioma later in life, but the ... from mesothelioma that is unrelated to radiation. Surviving Mesothelioma ... on its website. Click here to read it ... Australia compared the cases of 45 patients who had ...
Breaking Medicine News(10 mins):Health News:Auto Insurance Plans Are Cheaper During Spring! 2Health News:Dr. Jeffrey Martin Invited to Share Latest Breakthroughs in Cataract Care During Roundtable Discussion at National 2015 ASCRS Meeting In San Diego 2Health News:High Rates Of Car Theft Can Have An Impact on Auto Insurance Prices! 2Health News:New Study Examines Relationship Between Radiation for Hematologic Cancers and Development of Mesothelioma, According to Surviving Mesothelioma 2
(Date:4/17/2015)... HILL, N.C. , April 17, 2015  Regulatory ... the newly released bipartisan discussion draft called "21 st ... document is planned to be taken up by Congress ... how pharmaceutical and medical device products are developed and ... For that reason, many companies have begun to consider ...
(Date:4/17/2015)... Nonin Medical, a global leader in noninvasive medical monitoring, ... Steve Bucholz will retire May 1. Company founder ... Chief Executive Officer. In addition, Mr. Isaacson will continue ... transition to David Noel , Chief Financial Officer. ... to Nonin Medical,s growth," Mr. Isaacson said. "Under Steve,s ...
(Date:4/17/2015)... Research and Markets ( http://www.researchandmarkets.com/research/lmsnqn/medical_equipment ) ... Rental and Leasing - Global Strategic Business Report" ... the worldwide markets for Medical Equipment Rental and Leasing ... for the US, Japan , ... Annual estimates and forecasts are provided for the ...
Breaking Medicine Technology:21st Century Cures: A Regulatory Game-Changer for the Pharmaceutical Industry 2Nonin Medical's Philip Isaacson Expands CEO Role; President and COO Steve Bucholz to Retire May 1 2Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2
Cached News: