HOME >> MEDICINE >> NEWS
Obesity independently impacts prostate cancer screening

When interpreting prostate cancer screening test results, physicians should consider the impact of a patient's body mass index, regardless of race, according to a new study. Published in the November 15, 2006 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, the study found that obese African-American and Caucasian men had lower levels of prostate surface antigen (PSA) and free PSA (fPSA) than men with normal body mass index (BMI), suggesting that an obese man with a slightly elevated PSA may be at higher risk for prostate cancer than a man with normal BMI.

Screening for prostate cancer by measuring PSA levels is now widely available. While credited for detecting small, localized malignancies, an extremely high number of false positive interpretations result in ultimately unnecessary, risky, invasive investigations. For example, high PSA levels may be a malignancy or simply benign prostatic hypertrophy (BPH). Consequently, clinicians still debate its utility in patient care, and researchers look for factors that may affect PSA levels and more specific tests.

Epidemiology evidence shows that obese patients and African-Americans present with more advanced disease. Evidence suggests that body fat, indirectly measured by body mass index (BMI), decreases the amount circulating PSA. Height, too, has been shown to affect percent free PSA (%fPSA).

To further characterize the relationship of PSA, fPSA and %fPSA with BMI, height and race, the investigators interviewed and tested blood from 150 African-Americans and 149 Caucasians.

Jay H. Fowke, Ph.D. of the Vanderbilt University Medical Center in Nashville, and colleagues found PSA and fPSA levels decreased with increasing BMI. This inverse relationship was strongest in men under 60. Race did not effect any association between PSA or %fPSA and B
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
9-Oct-2006


Page: 1 2

Related medicine news :

1. Obesity linked to hyperparathyroidism in chronic kidney disease
2. Obesity increases risk of injury on the job
3. Obesity increases workers compensation costs
4. Obesity may be linked to middle ear effusions in children
5. Obesity surgery can lead to memory loss, other problems
6. Obesity and environmental chemicals -- New research probes potential link
7. Obesity could bankrupt the health system, warn doctors
8. Obesity linked to acid reflux disease
9. Obesity a growing problem in the Indo-Asian population
10. Obesity tied to higher risk of complications in spinal surgery, Jefferson neurosurgeon finds
11. Obesity in men linked to infertility

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/4/2016)... ... December 03, 2016 , ... The Lymphoma ... innovative lymphoma research and serving the lymphoma community through a comprehensive series of ... Wine Tasting Event in New York City, with long-time partners The Paul Foundation, ...
(Date:12/4/2016)... ... 2016 , ... Penrose Senior Care Auditors® was announced as ... at the 26th Annual SMU Cox Dallas 100™ Awards Ceremony and Banquet held ... Entrepreneurship. Dallas 100™, co-founded by the Caruth Institute, honors the ingenuity, commitment and ...
(Date:12/4/2016)... PITTSBURGH, PA (PRWEB) , ... December 04, 2016 , ... ... not enough. One must brush properly to achieve optimal results. This important necessity inspired ... saw a need for a way to ensure that people break or avoid bad ...
(Date:12/2/2016)... ... December 02, 2016 , ... On Dec. 2, 2016, ... Rock Hotel San Diego honoring the 2016 MPN Heroes—eight individuals who have made a ... going above and beyond the standard of care, demonstrating leadership within the MPN community ...
(Date:12/2/2016)... ... December 02, 2016 , ... FlexiSpot, a trusted name in ... trial program for all of the company’s desktop riser products. A simple application ... experience. , FlexiSpot’s unique desktop risers use an advanced dual gas spring hovering ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... Columbia , December 2, 2016 bioLytical Laboratories, un ... la Compañía, el INSTI HIV Self Test , a los miembros de ... ... INSTI HIV Self Test! (PRNewsFoto/bioLytical Laboratories) ...      (Photo: http://photos.prnewswire.com/prnh/20161201/444905 ) ...
(Date:12/2/2016)... -- According to the latest market report published ... Endoscope Reprocessors: Single Basin Automated Endoscope Reprocessors Product Type Segment ... 2024 " the global automated endoscope reprocessors market was valued at US$ 740.6 ... CAGR of 7.2% during an eight-year forecast period 2016-2024, to ... ...
(Date:12/2/2016)... , Dec. 2, 2016  PipelineRx, a leading medication ... be offering demonstrations of its SaaS-based telepharmacy platform, ... Health-System Pharmacists 2016 Midyear Clinical Meeting and Exhibition, ... . With nearly 300 hospital clients nationally, the ... technology designed to dramatically improve pharmacy operations, enhance ...
Breaking Medicine Technology:
Cached News: