HOME >> MEDICINE >> NEWS
Obesity independently impacts prostate cancer screening

When interpreting prostate cancer screening test results, physicians should consider the impact of a patient's body mass index, regardless of race, according to a new study. Published in the November 15, 2006 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, the study found that obese African-American and Caucasian men had lower levels of prostate surface antigen (PSA) and free PSA (fPSA) than men with normal body mass index (BMI), suggesting that an obese man with a slightly elevated PSA may be at higher risk for prostate cancer than a man with normal BMI.

Screening for prostate cancer by measuring PSA levels is now widely available. While credited for detecting small, localized malignancies, an extremely high number of false positive interpretations result in ultimately unnecessary, risky, invasive investigations. For example, high PSA levels may be a malignancy or simply benign prostatic hypertrophy (BPH). Consequently, clinicians still debate its utility in patient care, and researchers look for factors that may affect PSA levels and more specific tests.

Epidemiology evidence shows that obese patients and African-Americans present with more advanced disease. Evidence suggests that body fat, indirectly measured by body mass index (BMI), decreases the amount circulating PSA. Height, too, has been shown to affect percent free PSA (%fPSA).

To further characterize the relationship of PSA, fPSA and %fPSA with BMI, height and race, the investigators interviewed and tested blood from 150 African-Americans and 149 Caucasians.

Jay H. Fowke, Ph.D. of the Vanderbilt University Medical Center in Nashville, and colleagues found PSA and fPSA levels decreased with increasing BMI. This inverse relationship was strongest in men under 60. Race did not effect any association between PSA or %fPSA and B
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
9-Oct-2006


Page: 1 2

Related medicine news :

1. Obesity linked to hyperparathyroidism in chronic kidney disease
2. Obesity increases risk of injury on the job
3. Obesity increases workers compensation costs
4. Obesity may be linked to middle ear effusions in children
5. Obesity surgery can lead to memory loss, other problems
6. Obesity and environmental chemicals -- New research probes potential link
7. Obesity could bankrupt the health system, warn doctors
8. Obesity linked to acid reflux disease
9. Obesity a growing problem in the Indo-Asian population
10. Obesity tied to higher risk of complications in spinal surgery, Jefferson neurosurgeon finds
11. Obesity in men linked to infertility

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... ... Steven Tonkinson, 36, of Coconut Grove, Florida, ran the Miami Marathon on January ... year, he ran all 26.2 miles with a green 25-pound ShelterBox strapped to his ... This Sunday, while many are watching the Superbowl, Steven Tonkinson will strap on the ...
(Date:2/5/2016)... NY & Salt Lake City, UT (PRWEB) , ... February 05, ... ... Founder of Activz Whole-Food Nutrition , announced that the much-anticipated feature with author ... the New Really Cool Humans Amateur TV Network. , Each week, on his weekly ...
(Date:2/5/2016)... ... February 05, 2016 , ... The ... Popeyes Louisiana Kitchen restaurants, launched the 14th annual “Appetite for a Cure” campaign ... with muscular dystrophy, ALS and related diseases that severely limit strength and mobility. ...
(Date:2/5/2016)... ... February 05, 2016 , ... Freed-Hardeman University ... Allen have signed a joint enrollment and degree completion agreement. The agreement, ... and baccalaureate degrees at FHU|Dickson. , The agreement allows students to be ...
(Date:2/5/2016)... ... February 05, 2016 , ... US Sports Camps , official operators ... to direct high-performance kids yoga training. ChildLight Yoga Studio is centrally situated in the ... Boston. , ChildLight Yoga Studio founder Lisa Flynn expresses her excitement, “We are thrilled ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 4, 2016 For hospitals considering enrollment in ... participating in the program, the Health Resources and Services ... the , Mega-Guidance , could have significant impact on ... in September 2016. Essential Insights , ... , summarizes the Mega-Guidance,s key proposed changes, including a ...
(Date:2/4/2016)... , Feb. 4, 2016  The Senior Care ... Government Reform Committee Chairman Jason Chaffetz ... holding today,s hearing , "Developments in the ... increases and growing questions about abusive pharmacy benefit ... (R-UT) and Ranking Member Elijah Cummings (D-MD) ...
(Date:2/4/2016)... Feb. 4, 2016   Bernstein Liebhard LLP today ... the United States District Court for the District of ... "Class") consisting of all persons or entities who purchased common ... INSY ) from March 3, 2015 through January 25, ... of its officers with violations of the Securities Exchange Act ...
Breaking Medicine Technology:
Cached News: