HOME >> MEDICINE >> NEWS
Obesity independently impacts prostate cancer screening

When interpreting prostate cancer screening test results, physicians should consider the impact of a patient's body mass index, regardless of race, according to a new study. Published in the November 15, 2006 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, the study found that obese African-American and Caucasian men had lower levels of prostate surface antigen (PSA) and free PSA (fPSA) than men with normal body mass index (BMI), suggesting that an obese man with a slightly elevated PSA may be at higher risk for prostate cancer than a man with normal BMI.

Screening for prostate cancer by measuring PSA levels is now widely available. While credited for detecting small, localized malignancies, an extremely high number of false positive interpretations result in ultimately unnecessary, risky, invasive investigations. For example, high PSA levels may be a malignancy or simply benign prostatic hypertrophy (BPH). Consequently, clinicians still debate its utility in patient care, and researchers look for factors that may affect PSA levels and more specific tests.

Epidemiology evidence shows that obese patients and African-Americans present with more advanced disease. Evidence suggests that body fat, indirectly measured by body mass index (BMI), decreases the amount circulating PSA. Height, too, has been shown to affect percent free PSA (%fPSA).

To further characterize the relationship of PSA, fPSA and %fPSA with BMI, height and race, the investigators interviewed and tested blood from 150 African-Americans and 149 Caucasians.

Jay H. Fowke, Ph.D. of the Vanderbilt University Medical Center in Nashville, and colleagues found PSA and fPSA levels decreased with increasing BMI. This inverse relationship was strongest in men under 60. Race did not effect any association between PSA or %fPSA and B
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
9-Oct-2006


Page: 1 2

Related medicine news :

1. Obesity linked to hyperparathyroidism in chronic kidney disease
2. Obesity increases risk of injury on the job
3. Obesity increases workers compensation costs
4. Obesity may be linked to middle ear effusions in children
5. Obesity surgery can lead to memory loss, other problems
6. Obesity and environmental chemicals -- New research probes potential link
7. Obesity could bankrupt the health system, warn doctors
8. Obesity linked to acid reflux disease
9. Obesity a growing problem in the Indo-Asian population
10. Obesity tied to higher risk of complications in spinal surgery, Jefferson neurosurgeon finds
11. Obesity in men linked to infertility

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Obesity independently impacts prostate cancer screening

(Date:2/28/2015)... Indosoft Inc , developers of ... are pleased to announce the development of Q-Suite 5.9. ... versions of Q-Suite, this new version will include enhancements ... new features to the leading edge call center software. ... will add features to enhance security and protection. Administrators ...
(Date:2/28/2015)... Louis, MO (PRWEB) February 28, 2015 ... leading provider of outsourced sales, marketing and supply ... their client, BIOTA Botanicals, is bringing its award ... Celebrated worldwide, BIOTA Botanicals’ products are specifically created ... herbal care experts, BIOTA is committed to marrying ...
(Date:2/28/2015)... February 28, 2015 How would ... Strategic? , There are all kinds of different ... raise awareness of the advantages and applications of ... is launching a new product this spring called ... understand the connection between personality type, leadership, and ...
(Date:2/28/2015)... Javon Bea Mercy Health System ... as stroke capable by the State of Illinois, enabling ... Mercy Harvard Hospital. , The hospital was required to ... to treat stroke according to national standards of care ... patients to bypass hospitals not designated as an Emergent ...
(Date:2/28/2015)... My Shiney Hiney® LLC., the renowned brand in personal ... Nevada for the annual ASD Market Week tradeshow. , ... tradeshows and My Shiney Hiney will be one of the ... can be found at booth number C1663. , My Shiney ... hygiene brush and cleansing system exclusively created to clean and ...
Breaking Medicine News(10 mins):Health News:Indosoft Proudly Announces Q-Suite 5.9 Call Center Software for Asterisk 2Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 2Health News:BIOTA Botanicals Brings Thinning-Damaged Hair Solutions to the Hair Care Aisle at Walgreens 3Health News:PeopleKeys Launches The Leadership Report 2Health News:PeopleKeys Launches The Leadership Report 3Health News:Mercy Harvard Hospital Recognized as Leader in Stroke Care - Javon Bea 2Health News:My Shiney Hiney® to Participate in ASD Market Week 2015 2
(Date:2/27/2015)... February 27, 2015 ... Überwachungssystem für kongestive Herzinsuffizienz (CHF) in seiner ...     Die ... neuartiges Herzüberwachungssystem für Patienten mit kongestiver Herzinsuffizienz ... sie ein Finanzierungsvorhaben über 5 Mio. USD ...
(Date:2/27/2015)... YORK , Feb. 27, 2015 /PRNewswire/ ... are increasing in applications as their effectiveness ... firm Kalorama Information.  Kalorama Information says that ... is the most powerful tool in proteomic ... spec; MS) through its traditional techniques has ...
(Date:2/26/2015)... Ill. , Feb. 26, 2015  AbbVie ... 15 abstracts of studies in its neuroscience and ... during the 67 th American Academy of ... , from April 18-25. The accepted abstracts ... DUOPA, in addition to investigational treatments in AbbVie,s ...
Breaking Medicine Technology:Vectorious Medical Technologies schließt Finanzierungsvorhaben über 5 Mio. USD ab 2Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 2Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 3AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 2AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 3AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 4AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 5AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 6AbbVie's Ongoing Research in Neuroscience and Oncology will be Featured at the 2015 American Academy of Neurology Annual Meeting 7
Cached News: