HOME >> MEDICINE >> NEWS
Obesity linked to hyperparathyroidism in chronic kidney disease

For patients with chronic kidney disease (CKD), the risk of elevated levels of parathyroid hormone (PTH), or hyperparathyroidisma significant complication that increases the risk of cardiovascular problems and deathincreases along with body weight, reports a study in the September Clinical Journal of the American Society of Nephrology.

"We knew that in people with normal kidney function obesity leads to impairment in vitamin D metabolism and elevated PTH levels, but this phenomenon was never studied in patients with CKD," comments lead author Dr Csaba P. Kovesdy, of Salem VA Medical Center, in Salem, Va. "Since both obesity and hyperparathyroidism are very complex problems in CKD, establishing an association between the two is important because of potential prognostic and therapeutic implications."

The study was based on a database of 496 U.S. veterans with moderate to severe CKD who were not yet on dialysis. The database allowed the researchers to test the association between body weight and PTH levels, while accounting for a number of possible confounding factors.

The results showed a significant association between obesity and hyperparathyroidismas body mass index increased, so did PTH levels. The relationship between increased PTH and body weight was unaffected by age, race, diabetes, or other factors.

A further analysis was done to determine if the association was present in all patients with CKD or just certain subgroups. "Interestingly, we found that obesity was only associated with higher PTH levels in patients who also showed signs of malnutrition and inflammation," says Dr. Kovesdy. "This finding may be unique to patients with CKD. Besides providing a possible explanation for why PTH levels are higher in obese patients, it may also be important for prognostic reasons, since malnutrition and inflammation are among the major complications responsible for poor outcomes in CKD."

Parathyroid hormone pla
'"/>

Contact: Shari Leventhal
sleventhal@asn-online.org
202-416-0658
American Society of Nephrology
8-Aug-2007


Page: 1 2

Related medicine news :

1. Obesity increases risk of injury on the job
2. Obesity increases workers compensation costs
3. Obesity may be linked to middle ear effusions in children
4. Obesity surgery can lead to memory loss, other problems
5. Obesity and environmental chemicals -- New research probes potential link
6. Obesity could bankrupt the health system, warn doctors
7. Obesity linked to acid reflux disease
8. Obesity a growing problem in the Indo-Asian population
9. Obesity tied to higher risk of complications in spinal surgery, Jefferson neurosurgeon finds
10. Obesity independently impacts prostate cancer screening
11. Obesity in men linked to infertility

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... PurhealthRX , ... Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize ... providing a CBD form that can be easily incorporated into liquid products, while reducing ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Lori R. Somekh, ... member of ElderCounsel, a national organization of elder law and special needs planning attorneys. ... and rules. It also provides a forum to network with elder law attorneys nationwide,” ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... New York, NY (PRWEB) , ... October 13, 2017 , ... ... most influential people in business to advocate for action towards gender equality at their ... 18,000 views from around the globe, and reached a social audience of over 3 ...
(Date:10/13/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has released a ... books in the Holy Scriptures, Revelation. The Book of Revelation paints a picture of ... have tossed it off as mere rubbish, but Yisrayl Hawkins says that is because ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... WASHINGTON , Sept. 28, 2017 Cohen ... to advance the use of wearable and home sensors ... brain disorders. Early Signal Foundation, a nonprofit organization focused ... populations, will provide an affordable analytical system to record ... ...
(Date:9/25/2017)... AMSTERDAM , Sept. 25, 2017   ... Trial Master File solutions, today—from the IQPC Trial ... Amsterdam , NL)—announced that EastHORN Clinical Services ... its clinical programs and TMF management. EastHORN, a ... Montrium,s eTMF platform to increase transparency to enable ...
(Date:9/22/2017)... 22, 2017  As the latest Obamacare repeal effort ... Cassidy (R-LA) and Lindsey Graham (R-SC) ... medical device industry is in an odd place.  The ... 2.3% excise tax on medical device sales passed along ... covered patients, increased visits and hospital customers with the ...
Breaking Medicine Technology:
Cached News: