HOME >> MEDICINE >> NEWS
Older blood associated with worse outcomes after repeat heart surgery

ve long known that red blood cells undergo significant changes during their storage, but little had been known about whether or not these changes have any clinical implications for patients," Bennett-Guerrero said.

Previous studies of lower risk cardiac surgical patients found a link between age of transfused blood and adverse outcomes, but no risk of increased mortality, Bennett-Guerrero said.

"We hypothesized that the effects of storage duration would be more pronounced in patients who are more likely to receive multiple blood transfusions, such as those undergoing a repeat open-heart procedure," he said.

Lower-risk heart patients use an average of two units of blood, compared to the current study's high-risk population that received an average of five units of blood. The more units of blood a patient receives increased the probability of receiving an older unit of blood, Bennett-Guerrero said.

For their study, the researchers retrospectively analyzed the medical files of 321 patients who underwent a repeat open-heart procedure for coronary artery bypass or valve replacement between 1995 and 2001 and who received donated blood during surgery or recovery.

The team correlated the clinical findings for each patient with the number and age of the units of blood the patient received, statistically adjusting for a host of patient characteristics such as age, obesity, other diseases, number of units received and hypertension. For comparison purposes, the researchers assigned patients into four groups, based on the age of the oldest unit of blood they received: 1-19 days, 20-26 days, 27-30 days, 31-42 days.

The researchers found that increasing age of the blood corresponded significantly with an increased risk of death. "In terms of mortality, kidney damage and length of stay in the intensive care unit and hospital, we saw the rate of risk increase with each successive quartile," Bennett-Guerrero said.

Specifically,
'"/>

Contact: Richard Merritt
Merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
22-Jun-2006


Page: 1 2 3

Related medicine news :

1. Older motorists improve driving performance with physical conditioning
2. Older patients with major depression live longer with appropriate treatment, Penn study shows
3. Older, lower income patients least likely to see a specialist for lupus
4. Older adults face double whammy when it comes to body fat
5. Analysis: Older men treated for early prostate cancer live longer than those not treated
6. Older men treated for early prostate cancer live longer than those who are not
7. Older fathers more likely to have autistic children
8. Older, more rounded and artier applicants make better medical students
9. Older women have far fewer mammograms than they report
10. Older donor hearts just as good, University of Alberta study shows
11. Older children not smarter than their younger sibs, study finds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... , ... June 27, 2016 , ... "FCPX editors can ... inside of Final Cut Pro X," said Christina Austin - CEO of Pixel Film ... Final Cut Pro X users can now reveal the media of their ...
(Date:6/27/2016)... , ... June 27, 2016 , ... ... edge technology to revolutionize the emergency ambulance transport experience for the millions of ... of how Uber has disrupted the taxi industry through the use of technology. ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, ... Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility ... home to some of the world’s leading providers of cereal and other breakfast foods. ...
(Date:6/26/2016)... ... ... Kasmer, a legally blind and certified personal trainer is helping to develop a weight loss ... plans to fix the two major problems leading the fitness industry today:, ... , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... 2016 , ... Austin residents seeking Mohs surgery services, can now turn to ... Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to ... fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
Breaking Medicine Technology:
Cached News: