HOME >> MEDICINE >> NEWS
Older blood associated with worse outcomes after repeat heart surgery

ve long known that red blood cells undergo significant changes during their storage, but little had been known about whether or not these changes have any clinical implications for patients," Bennett-Guerrero said.

Previous studies of lower risk cardiac surgical patients found a link between age of transfused blood and adverse outcomes, but no risk of increased mortality, Bennett-Guerrero said.

"We hypothesized that the effects of storage duration would be more pronounced in patients who are more likely to receive multiple blood transfusions, such as those undergoing a repeat open-heart procedure," he said.

Lower-risk heart patients use an average of two units of blood, compared to the current study's high-risk population that received an average of five units of blood. The more units of blood a patient receives increased the probability of receiving an older unit of blood, Bennett-Guerrero said.

For their study, the researchers retrospectively analyzed the medical files of 321 patients who underwent a repeat open-heart procedure for coronary artery bypass or valve replacement between 1995 and 2001 and who received donated blood during surgery or recovery.

The team correlated the clinical findings for each patient with the number and age of the units of blood the patient received, statistically adjusting for a host of patient characteristics such as age, obesity, other diseases, number of units received and hypertension. For comparison purposes, the researchers assigned patients into four groups, based on the age of the oldest unit of blood they received: 1-19 days, 20-26 days, 27-30 days, 31-42 days.

The researchers found that increasing age of the blood corresponded significantly with an increased risk of death. "In terms of mortality, kidney damage and length of stay in the intensive care unit and hospital, we saw the rate of risk increase with each successive quartile," Bennett-Guerrero said.

Specifically,
'"/>

Contact: Richard Merritt
Merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
22-Jun-2006


Page: 1 2 3

Related medicine news :

1. Older motorists improve driving performance with physical conditioning
2. Older patients with major depression live longer with appropriate treatment, Penn study shows
3. Older, lower income patients least likely to see a specialist for lupus
4. Older adults face double whammy when it comes to body fat
5. Analysis: Older men treated for early prostate cancer live longer than those not treated
6. Older men treated for early prostate cancer live longer than those who are not
7. Older fathers more likely to have autistic children
8. Older, more rounded and artier applicants make better medical students
9. Older women have far fewer mammograms than they report
10. Older donor hearts just as good, University of Alberta study shows
11. Older children not smarter than their younger sibs, study finds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2017)... (PRWEB) , ... April 30, 2017 , ... PracticeMatch, a ... increase in projected attendance for this year’s physician career fairs, with this year’s RSVPs ... complete schedule for the 2017 calendar year of national physician career fairs is located ...
(Date:4/29/2017)... S.C. (PRWEB) , ... April ... ... Southeast’s leading software and web development company, today announced the launch of ... DonorBridge is a solution combining decades of software innovation and industry expertise ...
(Date:4/29/2017)... ... April 29, 2017 , ... TransDark is a set of dynamic transitions ... the next without having to set a single keyframe in Final Cut Pro ... video production. , TransDark features dynamic transitions that momentarily splits the RGB layers of ...
(Date:4/29/2017)... ... April 29, 2017 , ... Sterling Global Products ... fine retailers selling biodegradable, hanging flushable wipes dispensers and/or 42 count refill packs ... in San Antonio, Texas, operates more than 350 stores throughout Texas and expanding ...
(Date:4/29/2017)... ... April 29, 2017 , ... ... and recognize the positive impact veterinarians have on animal health and welfare as ... Organization for Animal Health (OIE) choose a theme each year and this year ...
Breaking Medicine News(10 mins):
(Date:4/21/2017)... Halo Labs announces the launch of a ... called the Horizon at PEGS 2017 in ... analyzes sub visible particulate matter in biopharmaceutical samples to ... early as candidate selection and pre-formulation. Halo ... organization Elion Labs for system validation. "We ...
(Date:4/20/2017)... -- Research and Markets has announced the ... Prospects: Addressing Production Complexities Through Risk Management and Quality ... ... and Market Prospects: Overcoming Production Complexities Through Risk Management ... the current trends in the global biosimilars market, with ...
(Date:4/20/2017)... 2017   ZappRx, Inc ., a digital health company ... today announced it closed $25 million in Series B funding ... based in Seattle that is part ... The Series B round included participation from SR One ... GV (formerly Google Ventures). As part of the ...
Breaking Medicine Technology:
Cached News: