Although it is widely agreed that amblyopia, a condition that involves poor vision and/or poor muscle control of one eye, can be effectively treated in children younger than six, it has generally been believed that older children were unlikely to benefit from treatment, according to background information in the article. The upper limit for successful treatment response has been believed to be six to seven or nine to ten years of age. The current study is designed to evaluate the effectiveness of treatment of amblyopia in children aged seven to 17 years.

Mitchell M. Scheiman, O.D., Richard W. Hertle, M.D., and colleagues in the Pediatric Eye Disease Investigator Group (PEDIG), conducted a randomized treatment trial of 507 older children with amblyopia at 49 clinical sites. All the patients were provided with optimal optical correction (children who already had glasses were given new ones). Children were then randomly assigned to receive treatment for amblyopia or to receive optical correction alone. Children aged seven to 12 in the treatment group were treated with two to six hours a day of patching over the sound eye combined with near visual activities such as playing with a GameBoy, homework, or reading, and one drop daily of atropine for the sound eye. Patients in the older treatment group (aged 13 to 17 years) were treated with patching and near visual activities alone.

Follow up visits occurred every six weeks for up to 24 weeks until the patients were classified as a responder or non-responder. A patient in the study was classified as a responder if the amblyopic eye acuity (sharpness of vision) was 10 or more letters (two lines on the eye c
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Contact: Ilena Ditoro
215-780-1284
JAMA and Archives Journals
11-Apr-2005