HOME >> MEDICINE >> NEWS
Older women who receive pelvic irradiation for cancer have increased risk for pelvic fracture

women with anal cancer, 14.0 percent in the irradiated group vs. 7.5 percent in the nonirradiated group; for women with cervical cancer, 8.2 percent in the irradiated group vs. 5.9 percent in the nonirradiated group; and for women with rectal cancer, 11.2 percent in the irradiated group vs. 8.7 percent in the nonirradiated group. The incidence of arm or spine fractures was similar in both groups.

"The observed hazard ratio for radiation therapy in women with anal cancer was 3.16. This value can be interpreted as a 3-fold increase in pelvic fracture risk for women with anal cancer who underwent radiation therapy (vs. women who did not) at any given time. The observed hazard ratio for radiation therapy in women with cervical cancer was 1.66; in women with rectal cancer, 1.65. These values indicate a lesser effect, but are still consistent with a substantial increase in fracture risk," the researchers write.

"Given the high baseline rate of fractures in women aged 65 years or older, the hazard ratio of 1.65 that we found in our study may represent an increased lifetime incidence of fractures from the baseline rate of 17 percent to 27 percent a substantial and clinically significant absolute increase."

"The high risk of pelvic fracture after radiation therapy for anal cancer may reflect the radiation therapy technique used to treat this disease. In the treatment of anal cancer, it is usually appropriate to treat the inguinal [pertaining to the groin] nodes because of the risk of disease at this site. Because of the location of these nodes with respect to the femoral head and neck, it has been difficult to treat these nodes well without concomitant irradiation of the femur, and thus the femoral heads are exposed to a relatively high irradiation dose in the treatment of anal cancer patients," the authors write.

The researchers add that it is important to note that the study population (older, predominantly white women) was already at hig
'"/>

Contact: Sarah Buss
612-624-2449
JAMA and Archives Journals
22-Nov-2005


Page: 1 2 3

Related medicine news :

1. Older motorists improve driving performance with physical conditioning
2. Older patients with major depression live longer with appropriate treatment, Penn study shows
3. Older, lower income patients least likely to see a specialist for lupus
4. Older adults face double whammy when it comes to body fat
5. Analysis: Older men treated for early prostate cancer live longer than those not treated
6. Older men treated for early prostate cancer live longer than those who are not
7. Older fathers more likely to have autistic children
8. Older, more rounded and artier applicants make better medical students
9. Older blood associated with worse outcomes after repeat heart surgery
10. Older women have far fewer mammograms than they report
11. Older donor hearts just as good, University of Alberta study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/29/2017)... ... 2017 , ... A New York high tech innovator and a Canadian not-for-profit ... of Artificial Intelligence (AI) in helping nudge men forward to be more proactive about ... of the Canadian Men’s Health Foundation (CMHF), whose mission is to inspire men to ...
(Date:5/28/2017)... ... ... HYPERAMS, LLC announced it will perform the inventory liquidation of ... The sale began this week and the inventory is expected to sell quickly. ... medical accessories, including blood pressure cuffs, stethoscopes, CPR masks, as well as blank polos, ...
(Date:5/28/2017)... ... 28, 2017 , ... Viewers likely know Rob Lowe from such 80s hits ... for his work on NBC’s The West Wing and Parks and Recreation. But recently, ... “Informed,” which puts the spotlight on important modern-day issues that face today’s society. One ...
(Date:5/27/2017)... ... ... In any business, follow up is critical to success. It is the same ... there will always be some patients who can’t or won’t make a immediate decision. ... it comes to presenting treatment. After the patient leaves, most practices end up ...
(Date:5/26/2017)... NY (PRWEB) , ... May 26, 2017 , ... Mediaplanet ... & Wound Care" campaign in USA Today, which will educate readers on how to ... of the campaign, a large focus is placed on melanoma. Dancing with the Stars ...
Breaking Medicine News(10 mins):
(Date:5/15/2017)... , May 15, 2017  Amy Baxter MD, chief ... leader in noninvasive pain relief, was awarded a 2017 ... magazine. Baxter was recognized at the MM&M Top 40 ... York City on May 10, 2017. The ... biopharma industry go "beyond the pill."  "Innovation ...
(Date:5/10/2017)... Global Health Intelligence (GHI), the leading healthcare data analytics ... 2017 ranking of the Best-Equipped Hospitals in Latin America ... GHI,s hospitals database for Latin America , which is ... database covers 86% of the hospitals in Latin ... each institution in key areas such as beds, medical specialties, ...
(Date:5/9/2017)... WASHINGTON , May 9, 2017  Demonstrating ... the board of directors for the Pharmaceutical Research ... criteria for membership. Biopharmaceutical companies will now have ... in order to be eligible to join PhRMA. ... criteria, the board is sending a clear message ...
Breaking Medicine Technology:
Cached News: