HOME >> MEDICINE >> NEWS
Once-a-year drug reduces fractures from osteoporosis

A treatment for osteoporosis delivered once a year is as effective as current monthly or weekly osteoporosis regimens at reducing the incidence of bone fractures, according to a new study led by a UCSF research team.

Results from a three-year, international study of 7,736 postmenopausal women with osteoporosis are reported in the May 3, 2007 issue of the "New England Journal of Medicine." Study findings also are available online at content.nejm.org.

The study showed that treatment with zoledronic acid (marketed as Reclast) was very effective in reducing the incidence of all types of fractures in women with postmenopausal osteoporosis, the researchers said. Impact included a 70 percent reduction in the risk of spinal fractures and a 40 percent reduction in the risk of hip fractures. The effect was sustained over three years.

"The reductions in hip and spine fractures were at least as large as those seen with other drugs in this category," said Dennis Black, PhD, a professor of epidemiology and biostatistics in the UCSF School of Medicine, who led the study. "But even more remarkable were the strong, significant and consistent effects across all fracture types."

Reclast is an investigational drug in the bisphosphonate drug category that is being developed by Novartis Pharmaceuticals Corp., a U.S. affiliate of the Swiss-based Novartis AG. It is the only once-yearly bisphosphonate treatment being studied for osteoporosis and is still in the approval process through the Food and Drug Administration.

Three other drugs in the bisphosphonate family (marketed as Fosamax, Actonel and Boniva) are currently available and most commonly used as a once per week or once per month pill.

"For the first time, women could have the option of being treated once a year for osteoporosis, instead of having to remember to take a weekly pill," Black said. "Adherence to these weekly and month
'"/>

Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
2-May-2007


Page: 1 2 3

Related medicine news :

1. Nonhormonal drug reduces hot flashes in men treated for prostate cancer
2. Circumcision reduces HIV infection risk
3. Retinol lotion reduces the fine wrinkles from natural aging of skin
4. Improving communication with families of dying patients reduces stress, anxiety and depression
5. New study: Pycnogenol reduces heart failure
6. Drinking farm milk reduces childhood asthma and allergies but raw consumption remains unsafe
7. Angioplasty reduces long-term cardiac risk among heart patients with silent ischemia
8. Once-yearly treatment significantly reduces bone fractures in women with postmenopausal osteoporosis
9. Studies suggest investigational agent reduces disease activity in MS
10. Smoking ban dramatically reduces air pollution in Irish pubs
11. Penn researchers find treatment for MS also reduces vision loss in MS patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/9/2018)... ... 2018 , ... Thousands of US women with FDA-approved silicone ... from The American Society of Plastic Surgeons (ASPS), The American Society for Aesthetic ... As an MRI is recommended by FDA after the first three years then ...
(Date:8/9/2018)... (PRWEB) , ... August 09, 2018 , ... ... LegitScript certification. LegitScript is a new verification process that substance abuse providers must ... LegitScript certified means we can reach more people to help.” , Helping ...
(Date:8/9/2018)... ... August 09, 2018 , ... ... as an Operating Partner and will have an exclusive relationship with the firm. ... the firm’s strategic planning, human capital sourcing, and deal origination, evaluation and diligence. ...
(Date:8/7/2018)... ... ... Josh Sprague, Founder and CEO of athletic goods company Orange Mud , ... , Accompanied by colleague Marvin Sandoval and equipped with Orange Mud’s Gear Vest, ... iconic mountain bike race courses in the world.” , Beginning in the town ...
(Date:8/7/2018)... ... 2018 , ... Today Springfield Creamery added six new Organic ... yogurts are made with milk from grass-fed cows who enjoy a diet of ... Nancy’s sources the milk from organic family-owned farms, all within 60 miles of ...
Breaking Medicine News(10 mins):
(Date:8/7/2018)... PLEASANTON, Calif. (PRWEB) , ... ... ... Chief Executive Officer, today announced the appointment of Richard A. Stark to assume the role of Sanarus ... will apply his 20+ years of strategic development, marketing and sales experience in medical ...
(Date:8/3/2018)... ... August 03, 2018 , ... LifeWIRE’s innovative patents in healthcare ... the 5,000-strong association of app companies and information technology firms across the mobile ... Method System and Computer Program Product” and subsequent patents are among those recognized ...
(Date:8/2/2018)... ... August 02, 2018 , ... What: The Wharton School is pleased to invite ... allow up to five business reporters who cover aspects of public policy to attend ... Each funding opportunity covers the cost of tuition, course materials, most group meals, ...
Breaking Medicine Technology:
Cached News: