HOME >> MEDICINE >> NEWS
Once-a-year drug reduces fractures from osteoporosis

A treatment for osteoporosis delivered once a year is as effective as current monthly or weekly osteoporosis regimens at reducing the incidence of bone fractures, according to a new study led by a UCSF research team.

Results from a three-year, international study of 7,736 postmenopausal women with osteoporosis are reported in the May 3, 2007 issue of the "New England Journal of Medicine." Study findings also are available online at content.nejm.org.

The study showed that treatment with zoledronic acid (marketed as Reclast) was very effective in reducing the incidence of all types of fractures in women with postmenopausal osteoporosis, the researchers said. Impact included a 70 percent reduction in the risk of spinal fractures and a 40 percent reduction in the risk of hip fractures. The effect was sustained over three years.

"The reductions in hip and spine fractures were at least as large as those seen with other drugs in this category," said Dennis Black, PhD, a professor of epidemiology and biostatistics in the UCSF School of Medicine, who led the study. "But even more remarkable were the strong, significant and consistent effects across all fracture types."

Reclast is an investigational drug in the bisphosphonate drug category that is being developed by Novartis Pharmaceuticals Corp., a U.S. affiliate of the Swiss-based Novartis AG. It is the only once-yearly bisphosphonate treatment being studied for osteoporosis and is still in the approval process through the Food and Drug Administration.

Three other drugs in the bisphosphonate family (marketed as Fosamax, Actonel and Boniva) are currently available and most commonly used as a once per week or once per month pill.

"For the first time, women could have the option of being treated once a year for osteoporosis, instead of having to remember to take a weekly pill," Black said. "Adherence to these weekly and month
'"/>

Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
2-May-2007


Page: 1 2 3

Related medicine news :

1. Nonhormonal drug reduces hot flashes in men treated for prostate cancer
2. Circumcision reduces HIV infection risk
3. Retinol lotion reduces the fine wrinkles from natural aging of skin
4. Improving communication with families of dying patients reduces stress, anxiety and depression
5. New study: Pycnogenol reduces heart failure
6. Drinking farm milk reduces childhood asthma and allergies but raw consumption remains unsafe
7. Angioplasty reduces long-term cardiac risk among heart patients with silent ischemia
8. Once-yearly treatment significantly reduces bone fractures in women with postmenopausal osteoporosis
9. Studies suggest investigational agent reduces disease activity in MS
10. Smoking ban dramatically reduces air pollution in Irish pubs
11. Penn researchers find treatment for MS also reduces vision loss in MS patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2020)... ... May 26, 2020 , ... Today TRC Companies (“ TRC ”) announced ... that will help business owners and leaders assess whether their organizations are prepared to ... offering from TRC is intended to assist business leaders evaluate their readiness relative to ...
(Date:5/26/2020)... ... May 26, 2020 , ... ... pandemic, medical centers across the United States are joining forces to start a ... who have worked tirelessly to save lives. #FitForTheFrontLine is a national fitness challenge ...
(Date:5/21/2020)... , ... May 21, 2020 ... ... Companion to the CRC’s Guide to Coordinating Clinical Research, CenterWatch eLearning , ... research management, The CRC Trainer: An Interactive Companion to the CRC’s Guide ...
(Date:5/21/2020)... ... May 21, 2020 , ... Summit Medical ... to deliver over one million FDA-compliant face shields — designed, engineered and manufactured ... the critical need for personal protective equipment (PPE) for both front-line health care ...
(Date:5/21/2020)... ... 21, 2020 , ... Having the cushion of an already ... already gained ground with the inherited reputation of quality, innovation, and professionalism. The ... an effective way for the ingredients to become immediately available to the cells. ...
Breaking Medicine News(10 mins):
(Date:6/3/2020)... HILL, N.C. (PRWEB) , ... June 03, 2020 , ... ... an active focus on implementing strict cleaning and hygiene protocols at all ... reviewed every area of their health and cleanliness procedures to safeguard and protect both ...
(Date:6/2/2020)... ... 2020 , ... Adoptive cell therapies have ushered in a ... two Chimeric Antigen Receptor T-Cell (CAR-T) therapies in 2017. In addition to CAR-Ts, ... Natural Killer (NKs) cells and Dendritic Cells (DCs). , In this webinar, presenters ...
(Date:6/2/2020)... , ... June 02, 2020 , ... ... and medical professionals, but confidence in those sources varies widely. A recent national ... Health Sciences finds that Americans are more likely to trust information that comes ...
Breaking Medicine Technology:
Cached News: