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Osteoporosis screening and treatment may be cost-effective for selected older men

cture was lower, ranging from 7.6 percent at age 65 years to 17.6 percent at age 85 years. The densitometry and treatment strategy modestly reduced the absolute 10-year incidence of clinical fractures by a range of 2.1 percent for 65-year-old men without a prior fracture to 4.5 percent among 85-year-old men with a prior fracture.

Regarding cost-effectiveness, universal bone densitometry followed by oral bisphosphonate therapy among those found to have osteoporosis for all men aged 70 years or older regardless of fracture history or other fracture risk factors is not cost-effective using current drug costs. However, this strategy may be cost-effective for men aged 65 years or older with a prior clinical fracture and for men aged 80 years or older without a prior fracture, assuming a societal willingness to pay per QALY gained of $50,000. This densitometry and treatment strategy may also be cost-effective for white men aged 70 years or older without a prior clinical fracture if the cost of oral bisphosphonate therapy is less than $500 per year or if the societal willingness to pay per QALY gained is $100,000.


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Contact: Jeremiah Whitten
952-993-6057
JAMA and Archives Journals
7-Aug-2007


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