HOME >> MEDICINE >> NEWS
Other highlights in the May 2 JNCI

Study Confirms Tamoxifen Prevents Breast Cancer in High-Risk Women

Women at high risk for breast cancer who have undergone a hysterectomy appear to benefit from taking tamoxifen to prevent breast cancer, according to an extended follow-up of the Italian Randomized Tamoxifen Trial.

The initial findings from the Italian trial showed no significant reduction in breast cancer risk with tamoxifen use. However, the National Surgical Adjuvant Breast and Bowel Projects Breast Cancer Prevention Trial found that tamoxifen reduced the risk of estrogen receptor-positive breast cancer.

Umberto Veronesi, M.D., of the European Institute of Oncology in Milan, and colleagues randomly assigned 5,408 healthy women who had a hysterectomy to receive tamoxifen or a placebo for five years.

After 11 years of follow-up, 136 women developed breast cancer74 in the placebo group and 62 in the tamoxifen group. Among low-risk women, rates of breast cancer were similar in the tamoxifen and placebo groups. But for women at high risk, breast cancer rates were lower for those taking tamoxifen. Women taking tamoxifen experienced more side effects, including hot flashes and heart problems, than women in the placebo group.

"A complete assessment of the baseline cardiovascular risk should become an important component of counseling women on the use of tamoxifen, particularly in the prevention setting," the authors write.

Contact: Donata Francese, European Institute of Oncology, dfrancese@consulenti-associati.it, +39 02 89 075034


Drug Combination Halts Tumor Growth Better Than Single Agent

Treatment with three drugs that inhibit the human epidermal growth factor receptor (HER) stops HER2-positive breast cancer tumor growth in mice better than treatment with just one or two of the drugs.

Grazia Arpino, M.D., Ph.D., of Baylor Colleg
'"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
1-May-2007


Page: 1 2 3 4

Related medicine news :

1. Other highlights in the Dec. 6 JNCI
2. Other illnesses play role in difference in breast cancer survival rates between blacks and whites
3. Other highlights in the October 5 JNCI
4. Other highlights in the July 20 JNCI
5. Other highlights in the May 18 JNCI
6. Other highlights in the May 4 JNCI
7. Research highlights from Thoracic Society Conference
8. SCAI highlights study using wireless technology to speed care of heart attack patients
9. SCAI Founders Lecture highlights remarkable progress in catheter-based aortic valve replacement
10. Latest IPCC report highlights need for integrated climate/human behavior models
11. New report highlights aromatase inhibitor side effects

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: