HOME >> MEDICINE >> NEWS
Ovary removal surgery elevates risk for dementia

ROCHESTER, Minn. -- Mayo Clinic researchers have found that ovariectomy, surgical removal of a woman's ovaries, raises her risk of developing dementia or cognitive impairment. Risk is especially increased if a woman has her ovaries removed at a young age.

The findings will be presented Wednesday at the American Academy of Neurology meeting in San Diego.

The researchers studied 1,209 women who had surgical removal of both ovaries and 1,302 women who had only one removed from 1950 to 1987 in Olmsted County, Minn., home of Mayo Clinic. They compared each of the women who had undergone ovary removal with women who had no ovaries removed and followed them over time to see whether they developed dementia or cognitive impairment. Dementia or cognitive impairment was determined by interviewing a family member who reported a diagnosis of dementia, or by a low score on a telephone cognitive test given to the affected individual.

Walter Rocca, M.D., M.P.H., Mayo Clinic neurologist and epidemiologist, and lead study author, proposes two possible theories to explain the increased risk: 1) low estrogen due to the ovary removal leads to decreased protection of a woman's brain from cognitive decline, or 2) the ovariectomy is innocent and variations in the genes a woman is born with dictate the need for ovary removal and also prompt development of dementia or cognitive impairment.

The researchers hypothesize that the risk of dementia or cognitive impairment is higher when the surgery takes place at a younger age -- removal of both ovaries before age 46 or one ovary before age 38 -- due to insufficient estrogen. Prior epidemiologic and laboratory studies have pointed to a role for estrogen in protecting the brain from aging.

Even though women with both ovaries removed are given hormone replacement therapy, Dr. Rocca says it's not for long enough for women who have the surgery at a young age.

"Estrogen supplementation normal
'"/>

Contact: Lisa Lucier
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
5-Apr-2006


Page: 1 2

Related medicine news :

1. New project to analyze why Polycystic Ovary Syndrome and insulin resistance are so closely linked
2. Ovary removal elevates risk for Parkinsons disease and parkinsonism
3. Childrens Hospital Boston neurosurgeons to perform brain tumor removal during live Web cast
4. Preventive ovary removal linked to early death in younger women, Mayo Clinic discovers
5. Image-guided biopsy can help patients avoid unnecessary kidney removal
6. Image guided biopsy may help patients avoid kidney removal
7. Photodynamic therapy is an alternative to removal of esophagus
8. ECG transmission from ambulance cuts time to direct clot removal
9. Use of laparoscopic procedure for gallbladder removal varies widely
10. No improvement in overall survival with lymph node removal in treatment of advanced ovarian cancer
11. HealthGrades study: Bariatric surgery patients have fewer complications at high-volume hospitals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/1/2020)... WASHINGTON (PRWEB) , ... April 01, 2020 , ... According ... women of reproductive age (13-44) in need of publicly funded contraception live in ... rule.” Nearly one-quarter of Minnesota’s counties have lost some or all of their Title ...
(Date:4/1/2020)... Va. (PRWEB) , ... April 01, 2020 , ... Global ... accounts, and forms for teams adjusting to new needs based on COVID-19. , As ... hurdle for groups of all types. , Zerion will extend support by offering free ...
(Date:3/30/2020)... (PRWEB) , ... March 30, 2020 , ... ... as the coronavirus pandemic sweeps the country. In an effort to keep frontline ... solutions are enabling police interaction with community members while minimizing direct contact. They ...
(Date:3/28/2020)... ... March 27, 2020 , ... The construction industry ... spread of the coronavirus. Operating under the designation as an essential business as ... and environmental protection projects in the downstate New York region. , While certain ...
(Date:3/28/2020)... ... 28, 2020 , ... iPatientCare, a pioneer in cloud-based ... solutions has expanded the availability of telehealth services and other initiatives to help ... has a big role in fighting coronavirus . Increasing the telehealth services across ...
Breaking Medicine News(10 mins):
(Date:4/2/2020)... ... , ... NCPDP has elected its 2020-2021 Board of Trustees. The new Board ... on Wednesday, May 6, 2020. , Election Results – Newly Elected Board Members:, ... elected to the Board of Trustees. , Morgan Bojorquez, Director, Pharmacy Clinical ...
(Date:4/2/2020)... ... , ... Caitlin Richardson, a University of Washington MEDEX Physician ... Scholarship. , The $1,000 scholarship, awarded biannually to U.S. students who show ... the students pay tuition and other college-related expenses. , Rhonda Abbe, Director of ...
(Date:4/1/2020)... ... April 01, 2020 , ... Care Station Medical Group -- In ... a number of changes to better care for our community. As New Jersey's leading ... and crafted new ways to offer medical care to patients coping with COVID-19. ...
Breaking Medicine Technology:
Cached News: