HOME >> MEDICINE >> NEWS
Panel offers guidelines on skin reactions to new class of cancer drugs

DURHAM, N.C., May 22 -- Skin reactions to a powerful new class of anti-cancer drugs are frequent, but manageable through a simple and rational treatment approach usually without the need to reduce the dose or interrupt treatment with potentially life-prolonging chemotherapy, according to an article in the May issue of "The Oncologist."

The special article presents the first recommendations on skin reactions to the new drugs, called Epidermal Growth Factor Receptor Inhibitors (EGFRIs). The guidelines were developed at an international multidisciplinary meeting, including medical oncologists, dermatologists, nurses, and pharmacists. "One important goal is to ensure that healthcare professionals and patients see EGFRI-associated dermatologic toxicity as manageable, thereby optimizing clinical benefit from continued and uninterrupted use of EGFRIs when possible," according to lead author Dr. Thomas J. Lynch, Jr., of Massachusetts General Hospital, Boston.

Treatment with EGFRIs has been shown to improve survival in patients with several types of cancer, including lung, pancreatic, and colorectal cancers. The drugs including erlotinib (Tarceva), cetuximab (Erbitux), and panitumumab (Vectibix) work by interfering with cell-signaling abnormalities that contribute to cancer development and growth.

Unfortunately, the EGFRIs carry a substantial risk of skin reactions more than half of treated patients have some type of skin toxicity, most commonly an acne-like rash. The reactions most likely occur because the receptor blocked by the drugs also performs key functions in normal skin. There is even evidence that the rash may be a sign that EGFRI anti-cancer treatment is working in some studies, patients with more severe skin reactions had better survival. The skin reactions are rarely so severe that the dosage is reduced or treatment stopped. Until recently, there was no strong scientific data to guide the treatment of skin reactions to EGFRIs
'"/>

Contact: George Kendall
gkendall@alphamedpress.com
919-680-0011
AlphaMed Press, Inc.
23-May-2007


Page: 1 2 3

Related medicine news :

1. Panel offers expert analysis on causes, prevention of stent thrombosis
2. Panel presents Agricultural Biosecurity & Sustainability Strategies at 2007 AAAS Meeting
3. Panel updates guidelines for treatment of adult HIV infection
4. Panel finds insufficient evidence to recommend for or against maternal-request Caesarean delivery
5. Panel calls for a new look at treatments commonly used for chronic insomnia
6. Hormone therapy offers new hope for ovarian cancer patients
7. TB test offers patients quicker and easier diagnosis
8. Supersize me mice research offers grim warning for Americas fast food consumers
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Stenting of abdominal arteries offers welcome relief for intestinal angina

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... a new practice in Glendale. While the office will be the first ... breast augmentation, tummy tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... Feeding ... care for children with Pediatric Feeding Disorder (PFD), is pleased to announce that the ... a stand-alone diagnostic code (R code) in the next edition of the U.S. ...
(Date:9/1/2020)... ... September 01, 2020 , ... Dr. Kiran Gill ... aesthetic surgery of the face, breast, and body. In 2018, she founded Aesthetics ... plastic surgery and aesthetic practice in Southwest Florida. Dr. Gill and her team ...
(Date:8/31/2020)... ... August 31, 2020 , ... The ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... 10th Anniversary of Blood Cancer Awareness Month (BCAM) and its international Light ...
(Date:8/31/2020)... OCEAN SPRINGS, Miss. (PRWEB) , ... August 31, ... ... Pharmaceuticals Plus (GCPP) recently donated 1,400 N95 face masks to medical first responders ... company has continued to make donations of personal protective equipment (PPE) medical ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... and ROCKWALL, Texas (PRWEB) , ... ... ... Powerful Preventative in the Fight Against Covid-19 , Advanced Penetration Technology, LLC, ... innovative healthcare solutions for patients utilizing non-prescription, Over The Counter (OTC) products, ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... laboratory technologies, will host the Agilent Science and Technology Virtual Symposium 2020 ... two-day symposium, Agilent will open a suite of Live webinars and Networking sessions, ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... has been appointed to serve as Secretary to the Board of Trustees and ... , Mile High United Way is a Denver-based nonprofit organization that fights for ...
Breaking Medicine Technology:
Cached News: