Papillomavirus vaccine could substantially reduce cervical cancer incidence

Administering Human Papillomavirus Vaccine (HPV) to both sexually active women and those who have never had sex could substantially reduce the incidence of HPV related cervical cancer and precancers, conclude authors of an Article published in this week's edition of the Lancet.

Cervical cancer is the second leading cause of death from cancer in women worldwide, and is caused by infection with oncogenic (cancer causing) types of human papillomavirus. Around 500,000 new cases are diagnosed each year, 80% in developing countries, resulting in 250,000 deaths.

Dr Kevin Ault, Emory University School of Medicine, Atlanta, Georgia, USA and colleagues from around the world formed the Future II Study Group to investigate the efficacy of the vaccine.

For women who have never had sex, the vaccine was 99% effective in stopping cervical cancer (adenocarcinoma in situ), and pre-cancerous lesions.

When data from women who could have been exposed was included, the vaccine efficacy was 44%.

The researchers enrolled over 20,000 women aged 15-26 from the Americas, Europe and Asia-Pacific in the study. Some 9,000 of these were given the full vaccine; around 1,200 were given a component of the vaccine and the rest a placebo.

The women involved were recruited at university student health centres, urban clinics, advertisements and by word of mouth. Healthy women who were not pregnant, had no report of a previous abnormal pap smear, and had a lifetime history of less than four to five sex partners were eligible.

The authors say that further follow-up of large trials will be needed to establish how long the vaccine remains effective.

They conclude: "The results of this quadrivalent HPV vaccine programme provide strong evidence that implementation of HPV vaccination campaigns in pre-adolescent girls and young adult women will reduce rates of cervical cancer worldwide."

In an accompanying comment, Dr Maur

Contact: Juliette Merchant

Page: 1 2

Related medicine news :

1. Papillomavirus vaccine could reduce rate of vulval and vaginal cancers
2. Traditional Chinese exercises may increase efficacy of flu vaccine
3. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
4. Study reveals gaps in vaccine financing for underinsured children
5. Trials underway for essential new TB vaccine
6. Hib vaccine: A critical ally in Asias effort to reduce child deaths
7. Progress toward an antitumor vaccine
8. Chemotherapy may enhance the effectiveness of brain tumor vaccines
9. OHSU Cancer Institute shows findings of immunotherapy vaccine in prostate cancer patients
10. International studies show high efficacy for HPV vaccine
11. Vaxfectin-formulated measles DNA vaccine elicits long-term protection in nonhuman primates

Post Your Comments:

(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... locations throughout Arkansas that offers insurance and financial preparation services, is providing an ... Rock City Rescue organization. , Rock City Rescue is a locally recognized nonprofit ...
(Date:10/13/2017)... PITTSBURGH, Pa. (PRWEB) , ... October 13, 2017 , ... ... the dark poses a problem. Fortunately, an inventor from Austin, Texas, has identified a ... access to medication in darkness or restricted lighting. As such, it eliminates the need ...
(Date:10/13/2017)... ... 13, 2017 , ... The International Association of Eating Disorders ... for the field of eating disorders, announces the opening of early registration for ... Florida at the Omni Resort at ChampionsGate. , The annual iaedp™ ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate ... primary prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton ... staged a mock evacuation of the facility as part of a disaster drill on ... Echo Hose EMS and Shelton City Emergency Manager, as well as the Connecticut ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... DIEGO , Oct. 12, 2017   Divoti USA ... Alert Jewelry up to the standard of the latest FDA requirements, ... June 2017). Anyone in need of Medical ID jewelry ... Medical Alert Jewelry are engraved in terms of the ... Divoti ...
(Date:10/11/2017)... Texas , Oct. 11, 2017  True ... services, has amplified its effort during National Breast ... about hereditary cancer risks. ... of Clinical Oncology calculated that more than 10 ... have inherited mutations in BRCA1 or BRCA2 and have ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
Breaking Medicine Technology:
Cached News: