Parasite genome sequences offer hope for new drugs and vaccines, Science studies say

This release is also available in French, Spanish and Portugese.

Scientists have sequenced and compared the genomes of three of the parasites responsible for sleeping sickness, Chagas disease and leishmaniasis, three devastating diseases of the developing world.

These parasites collectively cause disease and death in millions of humans each year, and the new genome sequences provide critical information for drug and vaccine developers, according to new research appearing in the 15 July 2005 issue of the journal Science, published by AAAS, the nonprofit science society.

In addition to offering drug and vaccine leads, the research provides a detailed roadmap of the biology and evolution of these unicellular organisms, or "protozoa," from the family Trypanosomatidae, which parasitize humans and other mammals, birds, reptiles, fish, insects and plants. Insects transmit these disease-causing parasites to humans living in tropical and subtropical regions of the world.

Researchers identified about 6,200 core genes that are present in all three parasites in a similar order within each genome. Some of the proteins encoded in these genes could serve as targets for drugs that would be effective against all three parasites, a worthy goal given the fact that there are currently no vaccines for these diseases, and only a few drugs, most of which are inadequate due to resistance, toxicity or expense.

The sequencing initiative also identified genes specific to each parasite and this information could be useful for parasite-specific drug and vaccine development efforts.

"Thanks to these studies, scientists are now much closer than they were five years ago to developing effective drugs against these

Contact: Ginger Pinholster
American Association for the Advancement of Science

Page: 1 2 3 4 5

Related medicine news :

1. Results of largest ever genome scan for autism out
2. Two central mysteries in genome inheritance solved at UCSD
3. St. Jude conducts first large-scale bird flu genome study
4. HIV inserts into human genome using a DNA-associated protein
5. Three deadly parasite genomes sequenced
6. Genetic on-off switches pinpointed in human genome
7. Leprosy genome tells story of human migrations, French researchers report in Science
8. Global warmings threat to New York region and how to avoid severe consequences
9. Widowhoods economic consequences harshest on minority women
10. UCLA expert to discuss medical consequences of meth abuse at AAAS
11. Numbers, sequences pose problems for Fetal Alcohol Syndrome children

Post Your Comments:

(Date:6/19/2019)... ... ... Ovation® Fertility scientists have been invited to present four pieces of research at ... in Vienna, June 23-26, 2019. , Ovation’s oral presentation about the use of artificial ... for Oral Presentation and the Fertility Society of Australia Exchange Award., ...
(Date:6/18/2019)... ... June 18, 2019 , ... Cosmetic Town, an online ... of cosmetic facial rejuvenation in June. The Cosmetic Town website will showcase cosmetic ... performing various methods of cosmetic facial rejuvenation and videos that take viewers behind ...
(Date:6/18/2019)... ... June 18, 2019 , ... NeoTract, a wholly ... field of urology, today announced that Aaron Berger, MD, Associated Urological Specialists, LLC ... designation recognizes that Dr. Aaron Berger has achieved a high level of training ...
(Date:6/16/2019)... NEWPORT BEACH, Calif. (PRWEB) , ... June 14, ... ... Data Protection / Cyber Security solutions, today announced it has received the ... showcasing the award winning DLP that Works Platform along with the latest additions ...
(Date:6/16/2019)... SPRINGFIELD, Mo. (PRWEB) , ... June 15, 2019 , ... ... Convoy of Hope has been committed to helping those in need around the world. ... people in more than 125 countries. Convoy’s work would not be possible without the ...
Breaking Medicine News(10 mins):
(Date:6/24/2019)... ... June 24, 2019 , ... The Conference Forum has announced ... place on September 17-18, 2018 at the Renaissance Waterfront Hotel in Boston, MA, with ... Scott Gottlieb, 23rd Commissioner of the FDA, has chosen DPharm to deliver his perspective ...
(Date:6/24/2019)... ... 24, 2019 , ... Enespro PPE , a manufacturer ... the electrical industry has today announced the release of its guide for companies ... Developing a Culture of Electrical Safety, is written to address the continued challenge ...
(Date:6/20/2019)... ... , ... ERT, a global data and technology company that ... experts will present a series of innovative and educational live sessions and posters ... Diego, June 23-27. , ERT’s industry-recognized thought leaders will share their knowledge on ...
Breaking Medicine Technology:
Cached News: