HOME >> MEDICINE >> NEWS
Participation in clinical trials does not appear to affect physician's adherence to guidelines

Physicians who participated in a pharmaceutical-sponsored clinical trial involving asthma medications maintained adherence to treatment guidelines but were more likely to prescribe the sponsor's drugs, according to a study in the June 21 issue of JAMA.

Pharmaceutical companies are frequently involved in clinical trials in general practice, and this may trigger an increase in the use of the sponsoring company's products due to the physicians' experience with these products. This effect may be further strengthened by close physician-company cooperation, which may create physician loyalty toward the company. The effect of participation in company-sponsored studies on drug preferences has not been evaluated in primary care.

Morten Andersen, M.D., Ph.D., of the University of Southern Denmark, Odense, and colleagues investigated the effects of physicians participating in a pharmaceutical company-sponsored clinical trial that was aimed at improving patients' use of asthma medicine. The study compared 10 practices that were conducting the trial on asthma medicine with 165 control (nontrial-conducting) practices in Funen County, Denmark. The study included 5,439 patients treated with asthma drugs from the trial-conducting practices and 59,574 patients from the control practices.

The researchers found that the prevalence of inhaled steroid use among asthma patients increased from 68.5 percent at baseline to 72.9 percent during the second observation year in trial-conducting practices and from 69.1 percent to 73.3 percent in control (nontrial-conducting) practices. There was no impact of participating in the trial on physicians' adherence to international treatment guidelines. Both trial-conducting and control practices had a gradually increased use of the trial sponsor's inhaled corticosteroids, from 74.8 percent to 81.5 percent in trial-conducting practices and from 73.6 percent to 76.6 percent in control practices. Trial-conducting practices were 2
'"/>

Contact: Morten Andersen, M.D., Ph.D.
mandersen@health.sdu.dk
JAMA and Archives Journals
20-Jun-2006


Page: 1 2

Related medicine news :

1. New contracts support clinical trials on antibiotic-resistant, community-acquired staph infections
2. Damon Runyon renews its $2.25 million investment to support young clinical cancer investigators
3. International journal group updates guidelines on registration of clinical trials
4. Urgent need for guidance on mobile phone use in clinical care
5. New prostate cancer clinical guidelines to be released
6. First clinical trial of gene therapy for childhood blindness
7. Acute coronary syndrome therapy improvements linked with fewer deaths and improved clinical outcomes
8. Taking the wraps off drug safety data from clinical trials
9. Preclinical results of Geovaxs AIDS vaccines demonstrate potential to protect against disease
10. 30+ AIDS vaccine clinical trials in 24 countries, research occurring on every continent
11. NIH-funded program co-directed by Mailman School of PH faculty to expedite clinical research process

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/17/2017)... ... , ... Elemental LED, a leading U.S. based engineering and technology ... products were honored with Architectural SSL Product Innovation Awards (PIA) for the ... division, Diode LED, provides a wide variety of superior quality linear, task, and accent ...
(Date:8/17/2017)... (PRWEB) , ... August 17, 2017 , ... ... to catalyze conversations in support of bold systems change models helping to achieve ... an event on September 21, 2017, “We the Future: Accelerating Sustainable Development Solutions” ...
(Date:8/17/2017)... FL (PRWEB) , ... August 17, 2017 , ... ... Emergency Room (ER) on Wednesday, August 16, to community partners. The newly renovated ... designated “Fast Track” area for minor emergencies, eight semi-private rooms to deliver patient ...
(Date:8/17/2017)... ... August 17, 2017 , ... An August 2 article on NextShark ... surgery, largely influenced by the growing popularity of “pretty boys” in both K-Pop and ... standards of male appearance are changing not only in the Asian nation, where plastic ...
(Date:8/17/2017)... ... August 17, 2017 , ... CareAcademy, a provider ... has raised $1.675 M in seed funding to further expand its course portfolio ... Venture Capital Fund are the company’s primary investors. , Founded in ...
Breaking Medicine News(10 mins):
(Date:8/11/2017)... , Aug. 11, 2017 DarioHealth Corp. ... mobile health and big data solutions, today announced that ... Monday, August 14 and host a conference call at ... 2017 operating and financial results and its strategy and ... be hosted by Erez Raphael , Chief Executive ...
(Date:8/7/2017)... 7, 2017 Zimmer Biomet Holdings, Inc. (NYSE and ... that its Board of Directors has approved the payment of ... of 2017. The cash ... about October 27, 2017 to stockholders of record as of ... of dividends are subject to approval of the Board of ...
(Date:8/4/2017)... 3, 2017  Agragen, LLC, a ... the biopharmaceutical, nutraceutical, and aquacultural feed sectors, announces ... lead drug candidates, AGR131.  This drug is designed ... the blood of patients suffering from inflammatory conditions ... disease. Biological ...
Breaking Medicine Technology:
Cached News: