HOME >> MEDICINE >> NEWS
Penn State research shows withdrawal drug offers relief for Crohn's sufferers

A Penn State College of Medicine pilot study suggests that a drug used to ease symptoms of alcohol and drug addiction may also bring relief to people with Crohn's disease, a chronic inflammatory disorder of the intestine that affects an estimated 500,000 Americans.

In the study, patients with diagnosed Crohn's disease were treated with a low dose of naltrexone, an FDA-approved drug used to ease symptoms of withdrawal from substance abuse, and monitored for improvement of symptoms for 12 weeks. Quality of life surveys were given every four weeks for 16 weeks.

Jill P. Smith, a gastroenterology specialist and researcher at the College of Medicine and Penn State Milton S. Hershey Medical Center, presented her findings recently in Los Angeles at the National Association of Gastroenterologists annual Digestive Diseases Week conference.

The results showed that 89 percent of participants showed an improvement with therapy, while 67 percent achieved remission of symptoms. The only side effect to treatment was sleep disturbance in some patients.

Typical treatment for Crohn's involves using steroids or corticosteroids, which suppress the immune system and can have other toxic side effects. Treatment is often time-intensive and expensive, as well.

"This is a novel approach to treating a common disease, and it's simple, it's safe, and it costs far less than current standards of treatment," Smith said. "We don't yet know the exact mechanisms involved in how it works, but we're working on that as well."

Smith initiated the study using a Dean's Feasibility Grant -- a program designed to encourage investigators to design trials in their area of expertise and seek outside funding. The National Institutes of Health (NIH) recently awarded the College of Medicine $500,000 for the team to continue the study.

In a related study, Smith and other College of Medicine researchers are studying the chemical and molecular mechanisms involv
'"/>

Contact: Megan W. Manlove
mwm18@psu.edu
717-531-8604
Penn State
26-May-2006


Page: 1 2

Related medicine news :

1. States taking action to insure nations 13.3M uninsured young adults
2. K-State researcher working on a way to make snack foods with extra fiber
3. State spending keeps childless seniors out of nursing homes
4. Mammography rates declining in the United States
5. States spending may help keep childless seniors independent
6. Conference honoring UH professor attracts researchers from United States, abroad
7. K-State National Agricultural Biosecurity Center director speaker at AAAS Biosecurity Symposium
8. Investment level in HIV prevention programs related to HIV incidence in the United States
9. States with higher levels of gun ownership have higher homicide rates
10. Nursing home or hospital: State policy has big impact on elderly
11. NC State start-up looks to turn lights out on flu, other viruses

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/19/2020)... ... , ... For weeks, SignatureCare Emergency Center has been preparing its emergency room ... that while we are still short of some critical safety equipment, medical equipment and ... measures to be complete. , The Houston, TX based company said it has distributed ...
(Date:3/19/2020)... ... March 19, 2020 , ... As confirmed cases of ... America’s response efforts. , “As a global humanitarian organization, Project HOPE’s mandate is always ... here at home,” said Rabih Torbay, President and CEO of Project HOPE. “We will ...
(Date:3/19/2020)... ... 2020 , ... “We wanted to solve the challenges of safely getting testing ... Radish Health. “A reliable at home testing kit that can be processed quickly allows ... the comfort of their own home, while maintaining the health of the general public." ...
(Date:3/16/2020)... and LEE’S SUMMIT, Mo. (PRWEB) , ... March ... ... Viracor Eurofins announced a partnership today to deliver testing for Coronavirus SARS-CoV-2 (the ... is the largest paired exchange program in the world and serves approximately 100 ...
(Date:3/15/2020)... ... ... 4 out of 5 Americans (82%) across party lines say it is ... countries. , Peter Yeo, President of the Better World Campaign said, “This poll shows ... the U.S., can battle a pandemic on its own.” , Two thirds of respondents ...
Breaking Medicine News(10 mins):
(Date:3/20/2020)... ... 21, 2020 , ... On March 19, 2020 Amramp installed a wheelchair ramp ... Valley. The ramp and platforms helped access the large intake triage trailer in the ... we install ramps that provide access to medical facilities and individual homes. This service ...
(Date:3/19/2020)... ... 19, 2020 , ... Combining multiple food allergies into a ... according to research scheduled for presentation at the 2020 American Academy of Allergy, ... situation with coronavirus disease 2019 (COVID-19). , A retrospective review was used ...
(Date:3/19/2020)... Ala. (PRWEB) , ... March 19, 2020 , ... As ... healthcare experts call for us to practice social distancing and, in some cases, self-quarantine ... be especially difficult for people who have underlying mental health issues. , Cindy ...
Breaking Medicine Technology:
Cached News: