HOME >> MEDICINE >> NEWS
Phase II study shows combination improves survival of metastatic melanoma patients

CHICAGO -- Two chemotherapy drugs combined with an agent that prevents the growth of blood vessels significantly delayed the spread of tumors in patients with metastatic melanoma, according to study findings presented today at the 2007 American Association of Clinical Oncology (http://www.asco.org/portal/site/ASCO) (ASCO) Annual Meeting.

In this phase II clinical trial of 53 patients, tumor growth was delayed by almost six months, whereas, typically, these cancers begin spreading again eight weeks after chemotherapy treatment, researchers say.

The researchers from Mayo Clinic (http://www.mayo.edu/) and the North Central Cancer Treatment Group (http://ncctg.mayo.edu/) (NCCTG), caution that while the findings are promising, they are preliminary.

"This is the most effective treatment we have ever tested at Mayo Clinic for this type of cancer, but the results need to be validated," says Svetomir Markovic, M.D., Ph.D. (http://mayoresearch.mayo.edu/mayo/research/staff/markovic_sn.cfm), a Mayo Clinic oncologist and the study's principal investigator. "It is important for the public to know there is hope for patients with melanoma."

The study was presented today by Domingo Perez, M.D., the lead author of the study who is a former oncology fellow at Mayo Clinic and is now in private practice in Minneapolis.

"The clinical benefit may seem small, but in the world of melanoma where there is very little progress, this is certainly a strong indication that the combination of chemotherapy with an antiangiogenic agent may be a valid treatment strategy for these patients. But the only way to know this for certain is a head to head comparison with the standard course of treatment," Dr. Perez says.

Melanoma that has metas
'"/>

Contact: Amy Reyes
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
3-Jun-2007


Page: 1 2 3

Related medicine news :

1. GSK announces launch of largest ever Phase III trial in lung cancer treatment
2. MacroChem completes patient enrollment for Phase II trial of EcoNail for treatment of onychomycosis
3. Drug combination proves effective against myeloma in Phase I trial
4. Researchers present Phase 2 clinical results for Acologix AC-100
5. Positive results for ACRUXs lead product in US Phase 3 trial
6. Ebola DNA vaccine produces immune responses in all fully vaccinated volunteers in Phase 1 trial
7. GroPep starts Phase 1 infertility trial
8. Bayer launches Phase III clinical study of Trasylol in elective spinal fusion surgery
9. Joint statement on Savvy Phase 3 trial in Ghana to test the effectiveness of Savvy Gel in preventing HIV
10. NIAID launches first Phase II trial of a global HIV/AIDS vaccine
11. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/19/2020)... ... March 19, 2020 , ... Therapies of The Rockies has Colorado’s back, ... crisis. TOTR welcome new telepractice patients across the country, as remote therapy services have ... to begin or resume your services safely! , Therapies of The Rockies is a ...
(Date:3/19/2020)... , ... March 19, 2020 , ... ... designed to teach Executive Function, shares a free Student Learning Exercise: ExQ® ... many parents and teachers are seeking resources to help with the immediate need ...
(Date:3/19/2020)... HAWTHORNE, N.J. (PRWEB) , ... March 19, 2020 , ... ... to the current operator, Family of Caring, on October 3, 2018 and is not ... statement about the recent news involving Family of Caring at Montclair. , “We are ...
(Date:3/19/2020)... Va. (PRWEB) , ... March 20, 2020 , ... With ... conducts clinical trials will look different than they do today. Be ready to implement ... Trial Requirements management report shows readers how to leverage the revised guidelines’ quality-by-design approaches, ...
(Date:3/16/2020)... ... March 16, 2020 , ... To avoid the potential ... Services Authority is implementing several new universal health and safety measures agency-wide. ... staff," said Dr. Monteic A. Sizer, executive director of Northeast Delta. "Extensive discussion ...
Breaking Medicine News(10 mins):
(Date:3/15/2020)... ... March 14, 2020 , ... Dr. Stephen Press of Upper Montclair Dental Associates ... a philosophy of high quality, patient-orientated dental care that always takes place in his ... all of his patient’s dental needs, ranging from routine cleanings, to fillings, to bruxism ...
(Date:3/15/2020)... ... March 14, 2020 , ... The ... not only of infection, but increased isolation. , “Senior living communities like Aldersgate ... right message gets to the right person at the right time,” says Kyle ...
(Date:3/13/2020)... ... March 13, 2020 , ... Let’s Talk Interactive, ... video conferencing platform, today announces the firm’s new COVID-19 Telehealth Response Platform as ... adequate control of the coronavirus. , The firm’s telemedicine solutions include the ability ...
Breaking Medicine Technology:
Cached News: