HOME >> MEDICINE >> NEWS
Porcine islets offer promise for human diabetic patients

ATLANTA -- Islet cell xenotransplantation presents a promising near-term solution to the critically low islet cell supply for humans suffering from type 1 diabetes, according to researchers from the Emory Transplant Center, the Yerkes National Primate Research Center of Emory University and the University of Alberta, Canada. The Emory/Yerkes researchers successfully transplanted and engrafted insulin-producing neonatal porcine islet cells harvested by the University of Alberta researchers into diabetic rhesus macaque monkeys, restoring the monkeys' glucose control and resulting in sustained insulin independence. This research, published in the February 26 advanced online edition of Nature Medicine, also examines the effectiveness of a costimulation blockade-based regimen developed at Emory proven to have fewer toxic side effects than currently used immunosuppressive regimens, and provides essential answers to the possibility of cross-species viral transmission, a common concern of xenotransplantation use in humans.

Islet cell transplantation has been successful in reversing type 1 diabetes in humans, but the limited availability of islet cells greatly diminishes the possibility of meeting the medical needs of more than one million Americans who have the disease. Each year, only 3,000 to 4,000 donor organs are available, and each organ can only produce enough cells for, at most, one transplant.

"To meet the needs of millions of people suffering from type 1 diabetes, we must find new donor sources to allow large-scale application of islet cell transplantation in humans," said Christian P. Larsen, MD, DPhil, director of the Emory Transplant Center and affiliate scientist at the Yerkes Research Center. "While there is much work to be done, these studies suggest the rejection response to porcine islets can be surmounted."

While the Emory/University of Alberta findings are similar to the recently publicized research conducted by the University o
'"/>

Contact: Stephanie McNicoll
stephanie.mcnicoll@emory.edu
404-727-9254
Emory University Health Sciences Center
27-Feb-2006


Page: 1 2 3

Related medicine news :

1. MRI can track survival of pancreatic islets after transplantation
2. U of M reaches milestone in diabetes research using pig islets
3. Hormone therapy offers new hope for ovarian cancer patients
4. TB test offers patients quicker and easier diagnosis
5. Panel offers guidelines on skin reactions to new class of cancer drugs
6. Supersize me mice research offers grim warning for Americas fast food consumers
7. Developments in tissue engineering offer new sources for stem cell treatments
8. Targeted nanoparticles incorporating siRNA offer promise for cancer treatment
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Vitamin D supplements may offer cheap and effective immune system boost against TB

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: