HOME >> MEDICINE >> NEWS
Post-mortem brain studies reveal features of mild cognitive impairment

The brains of patients with mild cognitive impairment display pathologic features that appear to place them at an intermediate stage between normal aging and Alzheimer's disease, although some patients with mild cognitive impairment develop other types of dementia, according to two studies in the May issue of Archives of Neurology, one of the JAMA/Archives journals.

Mild cognitive impairment--difficulty with thinking, learning and memory--is increasingly recognized as a neurologic transition stage between normal cognitive function and Alzheimer's disease, according to background information in both articles. Older adults with mild cognitive impairment, especially those with a variety known as amnestic (memory-related) mild cognitive impairment, are thought to have a higher risk of progressing to clinical Alzheimer's disease. Little is known about how this condition affects the physical structures of the brain.

In the first study, Ronald C. Petersen, Ph.D., M.D., Mayo Clinic College of Medicine, Rochester, Minn., and colleagues compared the findings in autopsy tissue of brains of 15 individuals who at the time of their death had amnestic mild cognitive impairment (average age 88.9 years) to those of 28 individuals who were clinically healthy at the time of their death and 23 patients who were believed to have Alzheimer's disease at death and had undergone autopsy. The patients with mild cognitive impairment were examined every year before their death, which occurred between Sept. 1, 1986, and Dec. 31, 2004.

Most of the patients did not meet the requirements for a post-death diagnosis of Alzheimer's disease. However, the changes to their brains as compared to those of individuals without cognitive difficulties were more similar to those of patients with Alzheimer's disease. For instance, the patients had begun developing neurofibrillary tangles, or tangles in the cell bodies of neurons. The number of tangles correlated with the severity
'"/>

Contact: Lisa Lucier
507-538-0844
JAMA and Archives Journals
8-May-2006


Page: 1 2

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. New research discovers independent brain networks control human walking
3. ADHD appears to be associated with depressed dopamine activity in the brain
4. First of its kind report on how children with brain tumors perform at school
5. Chemical in brain acts like a fuel gauge
6. Case study: cross-cultural bioethics training program helps fight African brain drain
7. Paying taxes, according to the brain, can bring satisfaction
8. Childrens brain responses predict impact of sleep loss on attention
9. Old memory traces in brain may trigger chronic pain
10. Stanford researchers track human stem cells transplanted into rat brain
11. Drug shows activity against brain metastases

Post Your Comments:
(Date:7/22/2014)... Plate Club you eat pretty much everything you put ... Cornell University study shows that the average adult eats 92% ... plate. "If you put it on your plate, ... of the forthcoming book, Slim by Design, Professor of Marketing ... Wansink and co-author Katherine Abowd Johnson analyzed 1179 diners and ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 As reported on ... a caller request to name her favorite beauty products, “ ... on to say that “ Botox has changed my ... the makeup chair preparing for her various, daily appearances. ... explained Ms. Ripa (see: goo.gl/shmTQM). , “I think that Kelly ...
(Date:7/22/2014)... The Beryl Institute announces its fifth ... Scholar Program. These offerings reinforce the Institute’s commitment to ... healthcare and the need for rigorous research to understand ... scholar programs are intended to encourage and support ... focusing on the patient experience before, during and after ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 The market ... the past few years, owing to novel medical indications ... BoNTs in the aging societies where physical appearance is ... by one player, current competitors, new companies and technologies ... As biosimilar BoNTs will put the price of 1st-gen ...
(Date:7/22/2014)... NJ (PRWEB) July 22, 2014 CarePoint Health ... recently elected as the President of the medical staff at ... Levine will serve as President, as voted on by the ... of the medical staff in relation to the administration at ... needs of physicians and to work to make the Medical ...
Breaking Medicine News(10 mins):Health News:Celebrity Botox: Kelly Ripa Confesses to Getting Botox Injections 2Health News:The Beryl Institute Opens Applications for 2014 Patient Experience Grant and Scholar Programs 2Health News:The Beryl Institute Opens Applications for 2014 Patient Experience Grant and Scholar Programs 3Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 2Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 3Health News:Botulinum Neurotoxins Marketplace Analysed in New La Merie Publishing Report Available at MarketPublishers.com 4Health News:Dr. Howard Levine Elected President of the Medical Staff at Bayonne Medical Center 2
(Date:7/22/2014)... , July 22, 2014  NeuroSigma, Inc. (NeuroSigma), ... focused on commercialization of its non-invasive Monarch ... and neuropsychiatric disorders, today announced that enrollment has begun ... nerve stimulation (eTNS) as adjunctive therapy for the treatment ... being conducted at the Olive View-UCLA Medical Center in ...
(Date:7/22/2014)... York , July 22, 2014 ... Partnerschaft für umfassenden Schutz von Pharmazeuten ... Österreich    Equashield ( ... Transfersystemen (Closed System Transfer Devices, CSTDs) für gefährliche ... einen Vertriebshändler und Hersteller von medizinischen ...
(Date:7/21/2014)... McCord Research, Inc. was recently granted ... This patent describes a method for accelerating wound ... inventor, Dr. McCord, this method includes administering or ... composition of an effective amount of hydroxytyrosol and ... such that the administration of the combination reduces ...
Breaking Medicine Technology:Enrollment Commences in NeuroSigma-Sponsored Pediatric Clinical Trial for the Treatment of Lennox-Gastaut Syndrome 2Enrollment Commences in NeuroSigma-Sponsored Pediatric Clinical Trial for the Treatment of Lennox-Gastaut Syndrome 3Enrollment Commences in NeuroSigma-Sponsored Pediatric Clinical Trial for the Treatment of Lennox-Gastaut Syndrome 4Enrollment Commences in NeuroSigma-Sponsored Pediatric Clinical Trial for the Treatment of Lennox-Gastaut Syndrome 5Equashield ernennt Medikus zu seinem exklusiven österreichischen Vertriebspartner für seine geschlossenen Arzneimitteltransfersysteme 2US Patent Office Grants McCord Research Endothelial Cell Treatment Patent 2
Cached News: