HOME >> MEDICINE >> NEWS
Post-mortem brain studies reveal features of mild cognitive impairment

The brains of patients with mild cognitive impairment display pathologic features that appear to place them at an intermediate stage between normal aging and Alzheimer's disease, although some patients with mild cognitive impairment develop other types of dementia, according to two studies in the May issue of Archives of Neurology, one of the JAMA/Archives journals.

Mild cognitive impairment--difficulty with thinking, learning and memory--is increasingly recognized as a neurologic transition stage between normal cognitive function and Alzheimer's disease, according to background information in both articles. Older adults with mild cognitive impairment, especially those with a variety known as amnestic (memory-related) mild cognitive impairment, are thought to have a higher risk of progressing to clinical Alzheimer's disease. Little is known about how this condition affects the physical structures of the brain.

In the first study, Ronald C. Petersen, Ph.D., M.D., Mayo Clinic College of Medicine, Rochester, Minn., and colleagues compared the findings in autopsy tissue of brains of 15 individuals who at the time of their death had amnestic mild cognitive impairment (average age 88.9 years) to those of 28 individuals who were clinically healthy at the time of their death and 23 patients who were believed to have Alzheimer's disease at death and had undergone autopsy. The patients with mild cognitive impairment were examined every year before their death, which occurred between Sept. 1, 1986, and Dec. 31, 2004.

Most of the patients did not meet the requirements for a post-death diagnosis of Alzheimer's disease. However, the changes to their brains as compared to those of individuals without cognitive difficulties were more similar to those of patients with Alzheimer's disease. For instance, the patients had begun developing neurofibrillary tangles, or tangles in the cell bodies of neurons. The number of tangles correlated with the severity
'"/>

Contact: Lisa Lucier
507-538-0844
JAMA and Archives Journals
8-May-2006


Page: 1 2

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. New research discovers independent brain networks control human walking
3. ADHD appears to be associated with depressed dopamine activity in the brain
4. First of its kind report on how children with brain tumors perform at school
5. Chemical in brain acts like a fuel gauge
6. Case study: cross-cultural bioethics training program helps fight African brain drain
7. Paying taxes, according to the brain, can bring satisfaction
8. Childrens brain responses predict impact of sleep loss on attention
9. Old memory traces in brain may trigger chronic pain
10. Stanford researchers track human stem cells transplanted into rat brain
11. Drug shows activity against brain metastases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2017)... Linda, Ca (PRWEB) , ... May 24, 2017 ... ... between effects and background. Understanind and choosing the most appropriate instruments for research ... prove critical in research finding. This webinar will focus on innovations in stereo ...
(Date:5/24/2017)... ... 2017 , ... Drs. Nicholas Rallis and Chris Chondrogiannis are ... years as clinical instructors for the reputable Full Mouth Rehabilitation continuing education (CE) ... private practitioners receive cutting-edge clinical training and learn how to perform full ...
(Date:5/24/2017)... ... May 24, 2017 , ... Myers Jackson is well known for auctioning ... sell luxury homes anywhere on the planet. The luxury home market is alive and ... Houston city-scapes. A quick search of “11 Spyglass Hill Auction will enlighten you on ...
(Date:5/24/2017)... TN (PRWEB) , ... May 24, 2017 , ... ... the addition of ExtraHop to its solutions portfolio. ExtraHop delivers an analytics-first approach, ... security of every IT system, from the datacenter to the cloud to the ...
(Date:5/24/2017)... ... May 24, 2017 , ... The CFOs included on this ... systems in the nation and help their organizations navigate the challenges in healthcare ... instrumental in developing successful hospital and health system strategy. , Becker's Hospital Review ...
Breaking Medicine News(10 mins):
(Date:5/6/2017)... May 5, 2017  Hill-Rom Holdings, Inc. (NYSE: HRC), ... 100,000 square feet to its Welch Allyn campus. ... commitment to bring more than 100 new jobs to ... Allyn has maintained a significant presence for more than ... new positions, a large portion of which will be ...
(Date:5/4/2017)... SAN DIEGO , May 4, 2017  The ... Clinical and Scientific Meeting— OBP Medical , a leading ... announced the launch of a new extra-small size and ... ER-SPEC vaginal specula. Already available in small, ... sizes makes OBP Medical,s line of single-use lighted specula ...
(Date:5/3/2017)... 3, 2017 A Catheterization Laboratory is ... healthcare facility. Commonly referred to as cath lab, ... diagnostic imaging technology to give physicians visual access ... these spaces, a team of physicians perform life-saving ... coronary intervention, congenital heart defect closure, stenotic heart ...
Breaking Medicine Technology:
Cached News: