HOME >> MEDICINE >> NEWS
Postmenopausal hormone therapy appears to increase risk of blood clots in veins

Estrogen therapy may increase the risk of venous thrombosis, the formation of blood clots in the veins, among postmenopausal women who have had their uterus removed, according to a study in the April 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Venous thromboembolism (VT), which includes the conditions deep vein thrombosis (a blood clot in a deep vein) and pulmonary embolism (a blood clot that travels to the lungs), affects about one adult per 1,000 years of life, according to background information in the article. Researchers suspect that hormone therapy may increase a woman's risk of developing VT. The largest study analyzing the relationship between hormone therapy and VT is the Women's Health Initiative (WHI), which included two large clinical trials. One WHI trial examined the effects of estrogen plus progestin and found that this combination of hormones appeared to increase the risk of VT.

J. David Curb, M.D., University of Hawaii and Pacific Health Research Institute, Honolulu, and colleagues analyzed data from the other WHI trial, in which the effect of estrogen alone was studied in 10,739 women aged 50 to 79 years. The participants were randomly assigned to take either combined equine estrogens (a mix of several estrogens) or placebo. They were followed for an average of 7.1 years, during which 197 women developed VT, including 144 with deep vein thrombosis, 91 with pulmonary embolism and 38 with both.

Of those 197 women who developed VT, 111 were taking estrogen and 86 were taking placebo. The risk of VT was slightly higher for women receiving estrogen therapy; was significantly increased for deep venous thrombosis, but not significantly increased for pulmonary embolism; and was highest in the first two years of therapy. Estrogen therapy appeared to affect risk more in women with higher physical activity levels and lower HDL (good) cholesterol. Overall, the risk of venous thrombosis associat
'"/>

Contact: Gregg Takayama
808-692-0988
JAMA and Archives Journals
10-Apr-2006


Page: 1 2

Related medicine news :

1. Postmenopausal women with heart disease should take aspirin
2. Low-carb diets effects linked to rise in newly identified starvation hormone
3. COX inhibitors may weaken protective qualities of estrogen hormone therapy
4. UW study to clarify safety, effectiveness of hormone therapy during menopause
5. Alternative hormone treatment could help fight against breast cancer
6. Reducing cardiovascular disease risk factors when discontinuing hormone replacement therapy
7. Your brain and hormones may conspire to make you fat
8. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
9. First step in developing heart hormone-based pill to control high blood pressure
10. Decline in breast cancer cases likely linked to reduced use of hormone replacement
11. Breast discomfort during hormone therapy may indicate increased risk for breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... ... February 09, 2016 , ... The ... Herberger’s and Younkers department stores, announced it has raised $176,000 to benefit the ... Holden Comprehensive Cancer Center at the University of Iowa, The Lynn Sage Cancer ...
(Date:2/9/2016)... City, Florida (PRWEB) , ... February 09, 2016 ... ... of cold therapy products, announced today the introduction of the newly designed, innovative ... maximum comfort and better cold therapy coverage for the injured arm and shoulder ...
(Date:2/9/2016)... ... 09, 2016 , ... i2i Systems, an early innovator and developer of population ... the latest KLAS report, Population Health Management 2015: How Far Can Your Vendor Take ... health management (PHM). The latest KLAS Report, leveraging over 200 user interviews, shines ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... newly redesigned website, federallabs.org . The site houses a wealth of federal ... federal technologies through the process called technology transfer (T2). As a network of ...
(Date:2/8/2016)... ... February 08, 2016 , ... The Valentine’s Season is famous for gift giving with ... others that they are loved. This year, for more than 5.6 million Americans suffering ... just won't be enough to remind them of the lives they’ve led and the people ...
Breaking Medicine News(10 mins):
(Date:2/9/2016)... February 9, 2016 QGEN ... collaboration with 10x Genomics to develop and promote ... and bioinformatics. --> QGEN ; Frankfurt ... 10x Genomics to develop and promote comprehensive solutions ... --> QIAGEN N.V. (NASDAQ: QGEN ...
(Date:2/9/2016)...   AllCare Plus Pharmacy announced today that ... Approval ® for Home Care Accreditation ... Gold Seal of Approval ® is a symbol ... safe and effective care.  --> ... rigorous on-site survey in January 2016. The survey reflected ...
(Date:2/9/2016)... 2016 Hearing protection devices refer to the ... to the inner ear. Hearing protection devices include earplugs, ... are recommended for users exposed to noise levels of ... HPD that are inserted in the ear canal to ... provide more natural sound perception with the help of ...
Breaking Medicine Technology:
Cached News: