HOME >> MEDICINE >> NEWS
Postmenopausal hormone therapy appears to increase risk of blood clots in veins

Estrogen therapy may increase the risk of venous thrombosis, the formation of blood clots in the veins, among postmenopausal women who have had their uterus removed, according to a study in the April 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Venous thromboembolism (VT), which includes the conditions deep vein thrombosis (a blood clot in a deep vein) and pulmonary embolism (a blood clot that travels to the lungs), affects about one adult per 1,000 years of life, according to background information in the article. Researchers suspect that hormone therapy may increase a woman's risk of developing VT. The largest study analyzing the relationship between hormone therapy and VT is the Women's Health Initiative (WHI), which included two large clinical trials. One WHI trial examined the effects of estrogen plus progestin and found that this combination of hormones appeared to increase the risk of VT.

J. David Curb, M.D., University of Hawaii and Pacific Health Research Institute, Honolulu, and colleagues analyzed data from the other WHI trial, in which the effect of estrogen alone was studied in 10,739 women aged 50 to 79 years. The participants were randomly assigned to take either combined equine estrogens (a mix of several estrogens) or placebo. They were followed for an average of 7.1 years, during which 197 women developed VT, including 144 with deep vein thrombosis, 91 with pulmonary embolism and 38 with both.

Of those 197 women who developed VT, 111 were taking estrogen and 86 were taking placebo. The risk of VT was slightly higher for women receiving estrogen therapy; was significantly increased for deep venous thrombosis, but not significantly increased for pulmonary embolism; and was highest in the first two years of therapy. Estrogen therapy appeared to affect risk more in women with higher physical activity levels and lower HDL (good) cholesterol. Overall, the risk of venous thrombosis associat
'"/>

Contact: Gregg Takayama
808-692-0988
JAMA and Archives Journals
10-Apr-2006


Page: 1 2

Related medicine news :

1. Postmenopausal women with heart disease should take aspirin
2. Low-carb diets effects linked to rise in newly identified starvation hormone
3. COX inhibitors may weaken protective qualities of estrogen hormone therapy
4. UW study to clarify safety, effectiveness of hormone therapy during menopause
5. Alternative hormone treatment could help fight against breast cancer
6. Reducing cardiovascular disease risk factors when discontinuing hormone replacement therapy
7. Your brain and hormones may conspire to make you fat
8. Sex and prenatal hormone exposure affect cognitive performance, Yerkes scientists find
9. First step in developing heart hormone-based pill to control high blood pressure
10. Decline in breast cancer cases likely linked to reduced use of hormone replacement
11. Breast discomfort during hormone therapy may indicate increased risk for breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... Carolina (PRWEB) , ... June 26, 2016 , ... ... of a new product that was developed to enhance the health of felines. The ... centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
Breaking Medicine Technology:
Cached News: