HOME >> MEDICINE >> NEWS
Potent spice works to block growth of melanoma in lab test

HOUSTON - Curcumin, the pungent yellow spice found in both turmeric and curry powders, blocks a key biological pathway needed for development of melanoma and other cancers, say researchers from The University of Texas M. D. Anderson Cancer Center.

The study, to be published in the August 15, 2005 issue of the journal Cancer, but available on line at 12:01 a.m. (EDT) on Monday, July 11, demonstrates how curcumin stops laboratory strains of melanoma from proliferating and pushes the cancer cells to commit suicide.

It does this, researchers say, by shutting down nuclear factor-kappa B (NF-kB), a powerful protein known to promote an abnormal inflammatory response that leads to a variety of disorders, including arthritis and cancer.

The study is the latest to suggest that curcumin has potent anticancer powers, say the researchers.

"The antioxidant, anti-inflammatory and anti-carcinogenic properties of curcumin derived from turmeric are undergoing intense research here and at other places worldwide," says one of the study's authors, Bharat B. Aggarwal, Ph.D., professor of cancer medicine in the Department of Experimental Therapeutics.

At M. D. Anderson, for example, dramatic results from laboratory studies have led to two ongoing Phase I human clinical trials, testing the ability of daily capsules of curcumin powder to retard growth of pancreatic cancer and multiple myeloma. Another Phase I trial is planned for patients with breast cancer, and given this news of curcumin's activity in melanoma, animal studies will soon begin, Aggarwal says.

Ground from the root of the Curcuma longa plant, curcumin is a member of the ginger family. It has long been utilized in India and other Asian nations for multiple uses: as a food-preservative, a coloring agent, a folk medicine to cleanse the body, and as a spice to flavor food (two to five percent of turmeric is curcumin, for example).

While researchers had thought curcumin prima
'"/>

Contact: Heather Sessions
hrsessions@mdanderson.org
713-792-0655
University of Texas M. D. Anderson Cancer Center
11-Jul-2005


Page: 1 2 3

Related medicine news :

1. Potential prostate cancer treatment improvements discovered by researchers at Cedars-Sinai
2. Potential heart benefit found in stem cells
3. Potential association between skin cancer cream and improvements of prematurely aged skin
4. Potential treatment for intracerebral hemorrhage under study
5. Potential pharmaceutical drugs in the field of cancer
6. Potential new treatment for insulin-dependent diabetes
7. Potential weak link between virus and liver cancer discovered
8. Improving coping skills benefits family caregivers of hospice patients with cancer
9. Hospice referral rates increase with intervention improving communication
10. New research discovers independent brain networks control human walking
11. NHLBI Asthma Clinical Research Networks and ALA ACRC Network to present at ATS 2007

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2017)... ... 2017 , ... Sharon Kleyne, America’s leading water researcher, advocate and feared enemy ... of making new water infrastructure a number one priority. “As we usher in a ... infrastructure to become a top priority of our new political change agents.” Kleyne pointed ...
(Date:1/23/2017)... (PRWEB) , ... January 23, 2017 , ... ... and production applications. However, choosing the right method is paramount to success. Selecting ... more often in situations where multiple persons use the same equipment. Rare or ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... the American Society of Anesthesiologists® (ASA®), the Foundation for Anesthesia Education and ... Orthopaedic Surgeons (AAOS) and the Cigna Foundation, encourages proposals supporting high quality ...
(Date:1/23/2017)... (PRWEB) , ... January 23, ... ... Partnership (SNP) has launched online education programs and resources at seafoodnutrition.org/programs and ... nutritional benefits of a seafood-rich diet. These resources have been developed for ...
(Date:1/22/2017)... ... January 22, 2017 , ... Phytocéane invites clients to take an exotic ... the world with ZANZIBAR MILKY CREAM. Inspired by the beauty of Zanzibar, a Tanzanian ... Oil and moisturizing vegetal coral to create this gentle, velvety body cream to envelop ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... 23, 2017 NeuroVive Pharmaceutical AB (Nasdaq ... a preclinical collaboration agreement with the Children,s Hospital of ... , M.D., a US key opinion leader in the mitochondrial ... ... compounds from NeuroVive,s research program, NVP015, in certain experimental disease ...
(Date:1/21/2017)... DIEGO , Jan. 20, 2017 ResMed (NYSE: ... 3B Medical ( Winter Haven, Florida ) today announced ... the parties. BMC and 3B will be permitted to sell their ... will make a one-time settlement payment to 3B to close the ... settlement did not include an admission of liability or wrongdoing by ...
(Date:1/21/2017)... & Faruqi, LLP, a leading national securities law firm, reminds ... KMPH ) of the federal securities class action lawsuit ... underwriters of the Company,s April 16, 2015 Initial Public Offering ... The lawsuit has been filed in the ... on behalf of all those who acquired KemPharm ...
Breaking Medicine Technology:
Cached News: