HOME >> MEDICINE >> NEWS
Predicting the risk of rheumatoid arthritis for early arthritis patients

Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis (RA) is a painful and potentially disabling autoimmune disease. A wealth of research supports early aggressive treatment with disease-modifying antirheumatic drugs (DMARDs) as the best course for preventing joint damage and avoiding the fate of a wheelchair. Still, the use of DMARDs, even the widely prescribed and generally safe methotrexate, brings the risk of liver damage and other serious complications.

Among those who seek out a doctor's help for joint pain and stiffness, the most common diagnosis is undifferentiated arthritis (UA), or arthritic symptoms that do not add up to a specific arthritic disease. Spontaneous remission occurs in 40 to 50 percent of UA sufferers, while about one-third develop RA. Physicians often face the tough choice of whether to initiate DMARD therapy immediately or to wait and see. To guide individual treatment decisions, researchers with the Early Arthritis Clinic at Leiden University Medical Center, The Netherlands, have found a formula to help determine whether patients who present with UA are likely to progress to RA. The February 2007 issue of Arthritis & Rheumatism (http://www.interscience.wiley.com/journal/arthritis) features their simple, reliable prediction rule for disease outcome.

Starting with clinical data for over 1,700 arthritis patients, the Leiden team identified 570 patients with recent-onset UA and monitored their disease for one year. At the culmination of follow-up, 177 of the original UA patients fulfilled the diagnostic criteria for RA and 150 had achieved remission; the remaining 94 had been diagnosed with another rheumatologic disease. Through a combination of questionnaires, physical examination, and blood samples, the team identified 9 clinical variables with independent predictive value for RA: sex, age, localization of symptoms, mornin
'"/>

Contact: Amy Molnar
amolnar@wiley.com
John Wiley & Sons, Inc.
30-Jan-2007


Page: 1 2

Related medicine news :

1. Predicting danger of flu pandemic rests on differences in affected population, says O.R. Forum
2. Predicting the quality of life for older adults
3. Predicting an answer to the threat of flooding
4. Predicting outcomes for kidney transplant patients
5. Predicting successful outcomes in living-donor liver transplants
6. Predicting cardiovascular problems in liver transplant patients
7. Predicting the risk of death in patients with known coronary artery disease
8. Predicting the future of primary care in England
9. Predicting the outcome of drug-induced liver disease
10. Predicting serious cardiac outcomes
11. Green tea compound may be a therapy for people with rheumatoid arthritis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: