HOME >> MEDICINE >> NEWS
Pregnancy research leads to progress on premature delivery

The University of Rochester has filed a patent on several ideas to help prevent early labor and the premature delivery of low-birth-weight babies. The discovery is an incremental step in an area of obstetrics that has seen little improvement in 20 years.

Mark Plessinger, Ph.D., assistant professor of Obstetrics and Gynecology at the University of Rochester Medical Center, discovered that certain proteins known as toll-like receptors (TLRs), located in the amniotic membranes of pregnant women, sometimes fuel a harmful inflammatory response. The inflammation, in turn, may cause the fetal membranes to rupture and lead to preterm labor.

The pending University patent protects the development of a chemical test to ascertain the effectiveness of drugs that could be used to treat women at greater risk of preterm delivery. Other claims of the patent protect the idea that once these agents are identified, a drug might be developed to block the TLRs and stop early labor.

Plessinger is showcasing the research this week in Toronto at the annual meeting of the Society for Gynecological Investigation. Although doctors today can treat women in early labor with antibiotics and other drugs designed to slow contractions, studies have demonstrated that this approach is often ineffective.

"I am optimistic that we have landed on a novel idea," Plessinger said, "although it is far from therapeutic intervention."

Premature delivery is when an infant is born before 37 weeks of pregnancy. It occurs in about 12 percent of pregnancies in the United States and is the leading cause of infant death, according to the National Vital Statistics Report for 2004. When premature babies do survive they often face many health problems.

To better understand what brings on preterm labor, Plessinger started by isolating the cells within the amniotic membranes. The membranes are balloon-like, wrapping around the fetus and the amniotic fluid in which the fetus
'"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
23-Mar-2006


Page: 1 2

Related medicine news :

1. Pregnancy and lactation may affect maternal behavior and coping skills
2. Pregnancy complications still high for women with diabetes
3. Pregnancy cravings can harm your oral health
4. Pregnancy complications increase womens risk of heart disease, death
5. Pregnancy, not high-risk behavior, predictor of STD testing among newly homeless youth
6. 1 of 2 pediatric kidney disease research centers in world established
7. Stanford researchers find culprit in aging muscles that heal poorly
8. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
9. Indiana University Imaging Center receives $6M grant for kidney research
10. Penn researchers discover novel pathway for increasing good cholesterol
11. New research discovers independent brain networks control human walking

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Pregnancy research leads progress premature delivery

(Date:2/27/2015)... With Spring’s wet weather on the way, it ... crawl spaces in mind. The latest article from ... regarding crawl space conditions and repairs. , Clean Crawls ... are confused as to how water is getting into their ... common ways is through cracks in the foundation, walls, ceiling, ...
(Date:2/27/2015)... Las Vegas, NV (PRWEB) February 27, 2015 ... helping bring health and wellness to Americans nationwide. Each month ... different aspects of health and wellness, and healthy living. In ... Awareness Week. National Sleep Awareness Week starts by ... of Daylight Savings. This year Sleep Awareness Week will start ...
(Date:2/27/2015)... If there is one thing that drives parents into a ... at their child’s school. While head lice are not particularly ... of a nightmare for many parents as they see the ... their child’s classroom. Just when they think the problem is ... Local lice removal company, Lice Troopers , reports that ...
(Date:2/27/2015)... County, CO (PRWEB) February 27, 2015 Philanthropy ... Kevin and Amy Smits help to restore that ... for the last six years, this husband/wife Realtor team gives ... the charities have remained the same while others have been ... of Assault provides a safe haven and counseling for ...
(Date:2/27/2015)... The report analyzes the primary growth factors, market ... market. It also assesses key players in the industry, ... , Celiac disease is an autoimmune disease that occurs ... disease often has a genetic predisposition. According to analysts, ... celiac disease across the globe. When gluten, a protein ...
Breaking Medicine News(10 mins):Health News:Crawl Space FAQs are Answered in Clean Crawls Latest Article 2Health News:Emassagechair Wants Shoppers to Think About the Benefits of Massage During National Sleep Awareness Week 2Health News:Emassagechair Wants Shoppers to Think About the Benefits of Massage During National Sleep Awareness Week 3Health News:Anxiety over head lice among Miami parents as surge in head lice cases reported by local lice removal company Lice Troopers 2Health News:Mr. And Mrs. Smits Proves That Altruism Works All Year Round 2Health News:Global Celiac Disease Market Counts on Drug Launch for Growth 2Health News:Global Celiac Disease Market Counts on Drug Launch for Growth 3
(Date:2/26/2015)... , Feb. 26, 2015  Today the National ... The psychological and physical side effects of pain medications ... painkillers, such as Vicodin and Oxycontin, are safer options ... overdose on prescription painkillers than on heroin and cocaine ... CEO of NSC. "Yet, these medications are marketed as ...
(Date:2/26/2015)... Every year many millions of donations are ... Nevertheless, year after year doctors and the medical profession ... test to determine the status of heart health in ... even though that technology is over 100 years old, ... know, (while most patients do not know) that EKG,s, ...
(Date:2/26/2015)... 2015  Spring Bank Pharmaceuticals, Inc., a clinical-stage ... of virus infections, today announced that Jonathan ... President of Finance, a newly created role.  Mr. ... activities, including financial planning and reporting, accounting and ... Jensen , President and CEO. ...
Breaking Medicine Technology:National Safety Council: Opioid prescription painkillers have hidden, deadly side effects 2National Heart Health Month In February 2Jonathan P. Freve, CPA, Joins Spring Bank Pharmaceuticals as Vice President of Finance 2
Cached News: