HOME >> MEDICINE >> NEWS
Pregnancy research leads to progress on premature delivery

The University of Rochester has filed a patent on several ideas to help prevent early labor and the premature delivery of low-birth-weight babies. The discovery is an incremental step in an area of obstetrics that has seen little improvement in 20 years.

Mark Plessinger, Ph.D., assistant professor of Obstetrics and Gynecology at the University of Rochester Medical Center, discovered that certain proteins known as toll-like receptors (TLRs), located in the amniotic membranes of pregnant women, sometimes fuel a harmful inflammatory response. The inflammation, in turn, may cause the fetal membranes to rupture and lead to preterm labor.

The pending University patent protects the development of a chemical test to ascertain the effectiveness of drugs that could be used to treat women at greater risk of preterm delivery. Other claims of the patent protect the idea that once these agents are identified, a drug might be developed to block the TLRs and stop early labor.

Plessinger is showcasing the research this week in Toronto at the annual meeting of the Society for Gynecological Investigation. Although doctors today can treat women in early labor with antibiotics and other drugs designed to slow contractions, studies have demonstrated that this approach is often ineffective.

"I am optimistic that we have landed on a novel idea," Plessinger said, "although it is far from therapeutic intervention."

Premature delivery is when an infant is born before 37 weeks of pregnancy. It occurs in about 12 percent of pregnancies in the United States and is the leading cause of infant death, according to the National Vital Statistics Report for 2004. When premature babies do survive they often face many health problems.

To better understand what brings on preterm labor, Plessinger started by isolating the cells within the amniotic membranes. The membranes are balloon-like, wrapping around the fetus and the amniotic fluid in which the fetus
'"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
23-Mar-2006


Page: 1 2

Related medicine news :

1. Pregnancy and lactation may affect maternal behavior and coping skills
2. Pregnancy complications still high for women with diabetes
3. Pregnancy cravings can harm your oral health
4. Pregnancy complications increase womens risk of heart disease, death
5. Pregnancy, not high-risk behavior, predictor of STD testing among newly homeless youth
6. 1 of 2 pediatric kidney disease research centers in world established
7. Stanford researchers find culprit in aging muscles that heal poorly
8. UCLA researchers awarded $9M contract for study identifiying antibiotic treatment for MRSA
9. Indiana University Imaging Center receives $6M grant for kidney research
10. Penn researchers discover novel pathway for increasing good cholesterol
11. New research discovers independent brain networks control human walking

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/31/2016)... ... ... More than 80 representatives of the Hepatitis B Foundation , Hepatitis C ... event on National Hepatitis Testing Day outside of Philadelphia City Hall to raise awareness ... liver cancer. , Foundation leaders and the citywide coalition they created, Hep B United ...
(Date:5/31/2016)... ... May 31, 2016 , ... Twenty years ago it was revolutionary: ... trying to silence the voices they hear. But this approach has proven transformative, both ... method has steadily gained credibility and now is used around the world, but it ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... ... attribute calls back to particular advertising campaigns, to monitor the performance of sales ... they can maximize conversions and revenue. The software allows customers to record, transcribe, ...
(Date:5/31/2016)... ... ... Like jewels in a crown, the multiple awards presented to Fayez Spa confirm ... day spa and one of Canada’s few accredited 5 Star Spas! , The ... spa services with hair and beauty services and has resulted in creating ...
(Date:5/31/2016)... ... , ... Spectrum Aquatics has launched a brand new ADA pool lift, the ... the user in mind. , “Over the last two years our key customers and ... lbs lift is a necessary requirement for certain facilities with specific needs,” said Nabil ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... TARE (Transarterial Radio-embolization) Using ... and Overall Decreased Use of Hospital Resource ... specialist healthcare company, has today announced the publication ... of ISPOR (International Society for Pharmacoeconomics and Outcomes ... using yttrium-90 glass microspheres is associated with cost ...
(Date:5/26/2016)... Since its commercial introduction in ... life science tool for conducting genetic studies in a ... in its new report that the industry sits on ... by a range of new applications in the clinical ... http://photos.prnewswire.com/prnh/20140723/694805 ) , Since the Human ...
(Date:5/25/2016)... PUNE, India , May 25, 2016 ... "Medical Animation Market by Type (3D, 2D, 4D), by ... Patient Education), by End User (Medical Device Manufacturers, Hospitals/ ... report studies the global Medical Animation Market for the ... expected to reach USD 301.3 Million by 2021 from ...
Breaking Medicine Technology:
Cached News: