HOME >> MEDICINE >> NEWS
Prescription drugs can interact with a variety of foods

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines. According to the July issue of General Dentistry, the Academy of General Dentistry's (AGD) clinical, peer-reviewed journal, foods can increase or decrease the activity and toxicity of orally-administered drugs (intravenous drugs are not altered).

One of the most studied of these interactions is the inhibition of CYP3A4 enzymes caused by grapefruit or its juice. CYP3A4 enzymes are responsible for the metabolism of more than 60 percent of orally-administered drugs. Drugs that interact with grapefruit include anti-infectives, anti-inflammatories, cardiovascular agents, central nervous system agents, estrogens, gastrointestinal agents, Histamine H1 antagonists, immunosuppressives, and erectile dysfunction drugs. Dental patients in particular should be aware of interactions with the sedatives triazolam, midazolam and diazepam which could cause excessive sedation.

As little as 6.0 oz of grapefruit juice may lower the amount of a drug needed to produce the desired effect, which could cause an overdose. The blood that absorbs nutrients passes through the liver before reaching the general circulatory system (the first-pass). The ability of a drug to successfully pass from the GI tract to the plasma is called its bioavailability. Grapefruit juice inhibits first-pass drug metabolism, increasing bioavailability.

Many elderly patients vacation or spend winters in southern states such as Florida, where they may be more likely to consume grapefruit and other fruits that may interact with prescribed medicines. The components of grapefruit juice believed to be clinically active are also found in limes, pumellos, and Seville oranges. Natural food products, citrus products and cabernet sauvignon wine are also known to interact with drugs. This interaction can increase the concentration of drugs in the bloods
'"/>

Contact: Jennifer Starkey
jennifers@agd.org
312-440-4341
Academy of General Dentistry
5-Oct-2005


Page: 1 2

Related medicine news :

1. How to market diet pills: Prescription and over-the-counter pills may increase unhealthy behavior
2. Prescriptions for health advice online
3. Prescription opioids the predominant choice among illicit opioid users
4. Prescription pain killers involved in more drug overdose deaths than cocaine or heroin in the US
5. Prescription flip-side: Guidelines for medication withdrawal
6. Prescriptions for headache almost twice as likely in middle aged women as men of same age
7. Prescription painkillers effective in patients with dormant inflammatory bowel disease
8. Prescription drug coverage: An essential service or fringe benefit?
9. Prescription of heroin is less costly for society
10. UIC researchers to develop new drugs to fight bioterrorism
11. Statin drugs may delay progressive artery damage in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/25/2017)... ... ... Facing medical needs with a newborn boy this spring, Crowley Maritime ... for employees that is uncommon in American business: 12 weeks of fully paid parental ... employees as new parents. It keeps our family life more stable. I can be ...
(Date:7/24/2017)... ... July 24, 2017 , ... ... kklaproth(at)robinsmorton(dot)com , Robins & Morton, Perkins Will, Newcomb & Boyd, Walter P ... of the new Destination Medical Building located at Mayo Clinic in Jacksonville, ...
(Date:7/24/2017)... (PRWEB) , ... July 24, 2017 , ... ... the federal Substance Abuse and Mental Health Services Administration’s (SAMHSA) State Targeted Response ... California Department of Health Care Services, will facilitate the development of a hub ...
(Date:7/24/2017)... ... July 24, 2017 , ... The International Essential Tremor Foundation (IETF) will ... essential tremor (ET). The seminar will take place on Saturday, Aug. 26 at the ... The program will run from 9 a.m. to 12 p.m., with check-in beginning at ...
(Date:7/24/2017)... ... July 24, 2017 , ... ... that already work hand-in-hand on an Innovation Collaboration program, have signed a five-year ... experience and cost of the care members and patients receive. The agreement also ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... RESEARCH TRIANGLE PARK, N.C. , July 21, ... UTHR ) announced today that it will report its ... on Thursday, July 27, 2017. ... Thursday, July 27, 2017, at 9:00 a.m. Eastern Time.  ... callers dialing 1-970-315-0533.  A rebroadcast of the teleconference will ...
(Date:7/19/2017)... , July 19, 2017  Mako Medical Laboratories ... and the Military Family Assistance Fund (MFA) to bring ... to visit with their families one last time ... to coordinate the travel and logistics needed for these ... deployed soldiers and their families. We just wish we ...
(Date:7/14/2017)... It should come as no surprise to anyone that ... of a crippling opioid epidemic. According to the Center ... deaths from opiate-based medications has quadrupled, Says, Dr. David ... 2001 to 2015". During this time, the prescription rate for ... a compelling link between prescription and eventual addiction. The problem ...
Breaking Medicine Technology:
Cached News: