HOME >> MEDICINE >> NEWS
Prescription drugs can interact with a variety of foods

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines. According to the July issue of General Dentistry, the Academy of General Dentistry's (AGD) clinical, peer-reviewed journal, foods can increase or decrease the activity and toxicity of orally-administered drugs (intravenous drugs are not altered).

One of the most studied of these interactions is the inhibition of CYP3A4 enzymes caused by grapefruit or its juice. CYP3A4 enzymes are responsible for the metabolism of more than 60 percent of orally-administered drugs. Drugs that interact with grapefruit include anti-infectives, anti-inflammatories, cardiovascular agents, central nervous system agents, estrogens, gastrointestinal agents, Histamine H1 antagonists, immunosuppressives, and erectile dysfunction drugs. Dental patients in particular should be aware of interactions with the sedatives triazolam, midazolam and diazepam which could cause excessive sedation.

As little as 6.0 oz of grapefruit juice may lower the amount of a drug needed to produce the desired effect, which could cause an overdose. The blood that absorbs nutrients passes through the liver before reaching the general circulatory system (the first-pass). The ability of a drug to successfully pass from the GI tract to the plasma is called its bioavailability. Grapefruit juice inhibits first-pass drug metabolism, increasing bioavailability.

Many elderly patients vacation or spend winters in southern states such as Florida, where they may be more likely to consume grapefruit and other fruits that may interact with prescribed medicines. The components of grapefruit juice believed to be clinically active are also found in limes, pumellos, and Seville oranges. Natural food products, citrus products and cabernet sauvignon wine are also known to interact with drugs. This interaction can increase the concentration of drugs in the bloods
'"/>

Contact: Jennifer Starkey
jennifers@agd.org
312-440-4341
Academy of General Dentistry
5-Oct-2005


Page: 1 2

Related medicine news :

1. How to market diet pills: Prescription and over-the-counter pills may increase unhealthy behavior
2. Prescriptions for health advice online
3. Prescription opioids the predominant choice among illicit opioid users
4. Prescription pain killers involved in more drug overdose deaths than cocaine or heroin in the US
5. Prescription flip-side: Guidelines for medication withdrawal
6. Prescriptions for headache almost twice as likely in middle aged women as men of same age
7. Prescription painkillers effective in patients with dormant inflammatory bowel disease
8. Prescription drug coverage: An essential service or fringe benefit?
9. Prescription of heroin is less costly for society
10. UIC researchers to develop new drugs to fight bioterrorism
11. Statin drugs may delay progressive artery damage in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/12/2018)... (PRWEB) , ... September 12, 2018 , ... De Novo ... **An FDAnews Webinar**, Sept. 25, 2018 — 1:30 p.m. – 3:00 p.m. ET, ... What applications are being granted by the FDA? , What are the best practices ...
(Date:9/7/2018)... , ... September 07, 2018 , ... ... and personal-care products with a presence worldwide, today announced that its Chief Executive ... Award in Entrepreneurship. Ms. Ishaq will be presented the award on Friday, September ...
(Date:9/2/2018)... TRUMBULL, Conn. (PRWEB) , ... ... ... Aesthetics & Mammography is proud to add HydraFacial MD® Elite to its ... treatment that uses patented, vortex-suction technology and an infusion of clinically-proven ingredients ...
(Date:9/1/2018)... (PRWEB) , ... September 01, 2018 , ... ... proclaimed by the International Veterinary Academy of Pain Management (IVAPM) that aims to ... Medical Association (TVMA) is partnering with IVAPM by educating pet owners of the ...
(Date:8/31/2018)... , ... August 31, 2018 , ... ... by the American Heart Association (AHA) to be responsive for procurement purposes. , ... purchasing managers may now reap the benefits. Companies like Pacific Medical Training are ...
Breaking Medicine News(10 mins):
(Date:8/31/2018)... ... August 31, 2018 , ... Many of ... as medications for cancer, mental health and required blood clotting agents used during ... Distress Syndroms (RDS) in premature babies and can be cost prohibitive – have ...
(Date:8/31/2018)... ... August 31, 2018 , ... The summertime sweat that many people dread ... a condition known as hyperhidrosis. In Grand Rapids , Dr. Brad Bengtson recognized ... women alike frequently soak through their shirts for no reason other than the fact ...
(Date:8/31/2018)... ... ... Travel tech specialist Aquarium Software has welcomed news that the Financial Conduct ... for the disabled. The move is an admission that some consumers continue to find ... living with a disability, Aquarium Software says thoughts now need to turn to how ...
Breaking Medicine Technology:
Cached News: