HOME >> MEDICINE >> NEWS
Prescription drugs can interact with a variety of foods

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines. According to the July issue of General Dentistry, the Academy of General Dentistry's (AGD) clinical, peer-reviewed journal, foods can increase or decrease the activity and toxicity of orally-administered drugs (intravenous drugs are not altered).

One of the most studied of these interactions is the inhibition of CYP3A4 enzymes caused by grapefruit or its juice. CYP3A4 enzymes are responsible for the metabolism of more than 60 percent of orally-administered drugs. Drugs that interact with grapefruit include anti-infectives, anti-inflammatories, cardiovascular agents, central nervous system agents, estrogens, gastrointestinal agents, Histamine H1 antagonists, immunosuppressives, and erectile dysfunction drugs. Dental patients in particular should be aware of interactions with the sedatives triazolam, midazolam and diazepam which could cause excessive sedation.

As little as 6.0 oz of grapefruit juice may lower the amount of a drug needed to produce the desired effect, which could cause an overdose. The blood that absorbs nutrients passes through the liver before reaching the general circulatory system (the first-pass). The ability of a drug to successfully pass from the GI tract to the plasma is called its bioavailability. Grapefruit juice inhibits first-pass drug metabolism, increasing bioavailability.

Many elderly patients vacation or spend winters in southern states such as Florida, where they may be more likely to consume grapefruit and other fruits that may interact with prescribed medicines. The components of grapefruit juice believed to be clinically active are also found in limes, pumellos, and Seville oranges. Natural food products, citrus products and cabernet sauvignon wine are also known to interact with drugs. This interaction can increase the concentration of drugs in the bloods
'"/>

Contact: Jennifer Starkey
jennifers@agd.org
312-440-4341
Academy of General Dentistry
5-Oct-2005


Page: 1 2

Related medicine news :

1. How to market diet pills: Prescription and over-the-counter pills may increase unhealthy behavior
2. Prescriptions for health advice online
3. Prescription opioids the predominant choice among illicit opioid users
4. Prescription pain killers involved in more drug overdose deaths than cocaine or heroin in the US
5. Prescription flip-side: Guidelines for medication withdrawal
6. Prescriptions for headache almost twice as likely in middle aged women as men of same age
7. Prescription painkillers effective in patients with dormant inflammatory bowel disease
8. Prescription drug coverage: An essential service or fringe benefit?
9. Prescription of heroin is less costly for society
10. UIC researchers to develop new drugs to fight bioterrorism
11. Statin drugs may delay progressive artery damage in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: