The study involved treatment resistant heroin addicts taking part in methadone maintenance programmes in six cities in the Netherlands. Prior to study entry, the heroin addicts frequently engaged in illegal activities to acquire money or drugs.

They were randomised to treatment with methadone plus heroin (experimental group) or with methadone alone (control group). After one year, data from 430 patients were analysed.

Co-prescription of heroin was associated with better quality of life measures. Although the costs of co-prescription were considerably higher, they were offset by lower costs of law enforcement and reduced costs of crime against property. The average total net savings amounted to 12,793 per patient per year.

From a societal perspective, supervised medical prescription of methadone plus heroin to chronic, treatment resistant addicts is very efficient.

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Contact: Emma Dickinson
edickinson@bmj.com
44-207-383-6529
BMJ-British Medical Journal
2-Jun-2005