HOME >> MEDICINE >> NEWS
Primary biliary cirrhosis more prevalent around toxic waste sites in NYC

According to a new study, exposure to toxins from hazardous waste sites may be a significant risk factor for developing primary biliary cirrhosis (PBC). Published in the March 2006 issue of Hepatology, researchers found significant clusters of the disease near Superfund toxic waste sites (SFS) and that the majority of patients in New York City who need liver transplants because of PBC, reside near SFS. Hepatology is published on behalf of the society by John Wiley & Sons, Inc., and is available online via Wiley InterScience at http://www.interscience.wiley.com/journal/hepatology.

PBC is an uncommon liver disease of unknown cause, though it reportedly appears in geographic clusters. Researchers, led by Aftab Ala, M.D. of Mount Sinai School of Medicine in New York City, examined the prevalence and potential clustering of PBC near New York City's most toxic waste sites, which are state-designated SFS.

The researchers collected zip code data on 172 patients in New York City in need of orthotopic liver transplant (OLT) between 1995 and 2003 due to either PBC or primary sclerosing cholangitis (PSC). They compared the patients' zip codes to zip codes of known SFS in the city. Of the city's 174 zip codes, 89 included or bordered SFS and 85 did not.

The researchers then calculated the expected prevalence of PBC-OLT and PSC-OLT, adjusting for demographic characteristics. They compared the mean standardized prevalence ratios in zip codes containing or adjacent to a SFS to the remaining zip codes. Lastly, they utilized SaTScan, a statistical software package, to detect specific clusters.

"The prevalence ratio of PBC-OLT, not PSC-OLT, was significantly higher in zip codes containing or adjacent to SFS," the authors report. The standardized prevalence ratio of PBC-OLT cases near SFS was statistically significantly higher than in zip codes that did not have, nor border with, a toxi
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
1-Mar-2006


Page: 1 2

Related medicine news :

1. Causes of primary biliary cirrhosis
2. Double the death rate from cirrhosis for blue collar men
3. Racial disparities in treatment of patients with cirrhosis and complications of portal hypertension
4. Relative risks of cirrhosis from non-alcoholic steatohepatitis
5. Increase in death rates from liver cirrhosis in Britain largest in western Europe
6. New specially coated non-stick tips stents help keep blood vessels open for cirrhosis patients
7. OPICAN study in seven Canadian cities reveals prescription opioid abuse more prevalent than heroin
8. Under-diagnosed rage disorder more prevalent than previously thought
9. Mild cognitive impairment prevalent in elderly population
10. Experts question prevalent stereotypes about autism
11. Womens silent health problem: Study finds fecal incontinence is prevalent in US women

Post Your Comments:
(Date:11/23/2014)... Pro Ace Care, a renowned Vancouver hot ... be providing an 8 year warranty on its selected hot ... went up due to the impending winter season, it was ... the premium service that the company provides. As a result, ... John Wood and Bradford hot water tanks. , “Every ...
(Date:11/23/2014)... 23, 2014 (HealthDay News) -- The holidays can be ... sensory overload can trigger major meltdowns, an expert says. ... best of circumstances, but when you have children with ... an occupational therapy professor at University of the Sciences ... "It,s best to let your hosts or visitors know ...
(Date:11/23/2014)... 23, 2014 To show thanks to new ... collection of white evening dresses for weddings. Customers ... 24/7. , iFitDress.com is a distinguished dress manufacturer, and it ... by worldwide customers for a very long time. The CEO ... a customer will be able to buy not only a ...
(Date:11/23/2014)... AngelWeddingDress.com has recently updated its online store, offering ... “If you are looking for gorgeous beach wedding dresses ... Here you can enjoy 70% off discounts and all ... big marriage ceremony is the most important dream of ... is uppermost priority. Ophelia, one of customers, said, “I ...
(Date:11/23/2014)... VA (PRWEB) November 23, 2014 The ... Have in Common, **FDAnews On-Demand Webinar**, Dec. 11, 2014 ... , The FDA’s focus on promotional activities is ... , Now they're looking at websites, Twitter, journal ... the calendar for Thursday, Dec. 11, for On-Demand access ...
Breaking Medicine News(10 mins):Health News:Pro Ace Care Now Gives 8 Year Guarantee on Selected Vancouver Hot Water Tanks 2Health News:Holidays Can Be Sensory Overload for Kids With Autism 2Health News:iFitDress.com: Wonderful White Evening Dresses Now Available 2Health News:Beach Wedding Dresses Added to Outstanding Online Dress Company AngelWeddingDress.com 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 2Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 3Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 4Health News:FDAnews Announces The FDA is Watching: What Twitter, Tradeshows and TV Have in Common, On-Demand Webinar, Dec. 11, 2014 5
(Date:11/22/2014)... , Nov. 21, 2014  Particle Sciences, Inc ... has developed and manufactured a new innovative vaginal ... Research and Development arm of Exeltis Pharmaceuticals.  According ... Project Management at Particle Sciences, "This vaginal ring ... our material sciences and modeling expertise.  We are ...
(Date:11/21/2014)... Mass. , Nov. 21, 2014  Alere Inc. ... rapid diagnostic tests, has appointed Juliet Cunningham ... role, Cunningham will be responsible for driving communications with ... execute on a series of changes to increase shareholder ... progress to investors," said Namal Nawana, Chief Executive Officer. ...
(Date:11/21/2014)... , Nov. 21, 2014  Tandem Diabetes Care ... a medical device company and manufacturer of the ... partnership with Tidepool, a non-profit dedicated to improving ... software platform that increases diabetes data accessibility. This ... which is currently under development, to download and ...
Breaking Medicine Technology:Particle Sciences' Clinical Trial Supplies Group Manufactures Innovative Vaginal Ring 2Alere Appoints Juliet Cunningham to Lead Investor Relations 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 2Tandem Diabetes Care Announces Partnership with Tidepool to Further Expand Access to Diabetes Device Data 3
Cached News: