HOME >> MEDICINE >> NEWS
Primary biliary cirrhosis more prevalent around toxic waste sites in NYC

According to a new study, exposure to toxins from hazardous waste sites may be a significant risk factor for developing primary biliary cirrhosis (PBC). Published in the March 2006 issue of Hepatology, researchers found significant clusters of the disease near Superfund toxic waste sites (SFS) and that the majority of patients in New York City who need liver transplants because of PBC, reside near SFS. Hepatology is published on behalf of the society by John Wiley & Sons, Inc., and is available online via Wiley InterScience at http://www.interscience.wiley.com/journal/hepatology.

PBC is an uncommon liver disease of unknown cause, though it reportedly appears in geographic clusters. Researchers, led by Aftab Ala, M.D. of Mount Sinai School of Medicine in New York City, examined the prevalence and potential clustering of PBC near New York City's most toxic waste sites, which are state-designated SFS.

The researchers collected zip code data on 172 patients in New York City in need of orthotopic liver transplant (OLT) between 1995 and 2003 due to either PBC or primary sclerosing cholangitis (PSC). They compared the patients' zip codes to zip codes of known SFS in the city. Of the city's 174 zip codes, 89 included or bordered SFS and 85 did not.

The researchers then calculated the expected prevalence of PBC-OLT and PSC-OLT, adjusting for demographic characteristics. They compared the mean standardized prevalence ratios in zip codes containing or adjacent to a SFS to the remaining zip codes. Lastly, they utilized SaTScan, a statistical software package, to detect specific clusters.

"The prevalence ratio of PBC-OLT, not PSC-OLT, was significantly higher in zip codes containing or adjacent to SFS," the authors report. The standardized prevalence ratio of PBC-OLT cases near SFS was statistically significantly higher than in zip codes that did not have, nor border with, a toxi
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
1-Mar-2006


Page: 1 2

Related medicine news :

1. Causes of primary biliary cirrhosis
2. Double the death rate from cirrhosis for blue collar men
3. Racial disparities in treatment of patients with cirrhosis and complications of portal hypertension
4. Relative risks of cirrhosis from non-alcoholic steatohepatitis
5. Increase in death rates from liver cirrhosis in Britain largest in western Europe
6. New specially coated non-stick tips stents help keep blood vessels open for cirrhosis patients
7. OPICAN study in seven Canadian cities reveals prescription opioid abuse more prevalent than heroin
8. Under-diagnosed rage disorder more prevalent than previously thought
9. Mild cognitive impairment prevalent in elderly population
10. Experts question prevalent stereotypes about autism
11. Womens silent health problem: Study finds fecal incontinence is prevalent in US women

Post Your Comments:
(Date:8/28/2014)... Alexandria, VA (PRWEB) August 28, 2014 ... Foundation (Meso Foundation) is able to accept donations in ... give. The Bitcoin donation page can be found at ... businesses are accepting Bitcoin as a form of payment, ... the same,” said Meso Foundation’s chief executive officer, Melinda ...
(Date:8/28/2014)... an internationally famous designer and leader in the formal ... fall bridesmaid dresses for the global clients. ... is now providing big discounts for all these trendy ... are offered in many fashionable colours. A lot of ... $190. UWDress.com’s kind officials always take everyone’s budget into ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 HORNE LLP ... of the accounting industry. The $67 million firm has ... the industry may hang in the balance. , Described ... storm,” a mass exit of Baby Boomers creating succession ... high turnover rates are creating culture wars within firms ...
(Date:8/28/2014)... women who are given information about the chance of ... fully understand the risks involved, according to research published ... today (Friday). , In a survey of around 2,200 ... (UCL) found that 64 per cent felt they fully ... that screening will pick up cancers that would never ...
(Date:8/28/2014)... FL (PRWEB) August 28, 2014 ... Recovery Month throughout September. This month will be ... treatment and mental health services. Along with other ... Group is helping to spread the word about ... in 1989, honoring the work of treatment and ...
Breaking Medicine News(10 mins):Health News:Cancer Research Funding Organization Now Accepts Bitcoin Donations 2Health News:Fashionable Fall Bridesmaid Dresses From UWDress.com 2Health News:HORNE LLP Proclaims War on Accounting Firm Culture 2Health News:Some women still don't underststand 'overdiagnosis' risk in breast screening 2Health News:Millennium Treatment Group Celebrates National Recovery Month 2
(Date:8/28/2014)... CHARLOTTE, N.C. , Aug. 28, 2014 /PRNewswire/ ... innovation marketplace, today announced a worldwide search for ... of the senior population.  Promising ideas uncovered through ... presented to leading medical device manufacturers and healthcare ... to improve the lives of individuals age 65 ...
(Date:8/28/2014)... 2014 /PRNewswire-iReach/ -- Gateway Analytical announced today that ... Annual Global Pharma Manufacturing Summit in ... . The Global Pharma Manufacturing Summit offers a ... and biologic pharmaceutical manufacturing. The conference is focused ... face, such as the increasing pressure to grow ...
(Date:8/28/2014)... DIEGO , Aug. 28, 2014 Telik, ... development company that merged with MabVax Therapeutics, Inc. ... made significant progress related to the development of ... antibody was recovered using the Company,s internally developed ... the potential for multiple antibody based therapeutic and ...
Breaking Medicine Technology:Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 2Edison Nation Medical Launches Open Innovation Search to Uncover Innovative Senior Care Products 3Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 2Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 2Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 4
Cached News: