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RNA splicing occurs in nerve-cell dendrites

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By revealing the capacity of mRNA splicing in dendrites, the investigators hope to develop an understanding of its role in cognition and dysfunction. Eberwine and colleagues are now working to find an endogenous mRNA that will undergo splicing within dendrites.

Co-authors in addition to Eberwine, Glanzer, and Miyashiro are Jai-Yoon Sul, Lindy Barrett, Brian Belt, and Phillip Haydon, all from Penn. This worked was funded by the National Institute on Aging and the National Institute on Mental Health.


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Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
7-Nov-2005


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