HOME >> MEDICINE >> NEWS
Radiotherapy advance points way to noninvasive brain cancer treatment

With an equal rate of incidence and mortality-the number of those who get it, and the number of those who die from it-Glioblastoma Multiforme (GBM) is a brain cancer death sentence.

Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half will die within a year, and the rest within 3 years. Currently, the only treatments that stretch survival limits are exceptionally invasive surgeries to remove the tumor and radiation treatment with the maximum tolerated dose - all of which leads to a painfully low quality of life. Because of this, researchers are racing to find better therapies to stop or slow GBM.

In the Jan. 1, 2006 issue of the journal Clinical Cancer Research, Gelsomina "Pupa" De Stasio, professor of physics at the University of Wisconsin-Madison, and her colleagues report on research into using a new radiotherapy technique for fighting GBM with the element gadolinium. The approach might some day lead to less invasive treatment and possibly a cure of this disease.

"It's the most lethal cancer there is. The only good thing about it is that, if left untreated, death is relatively quick and pain-free, since this tumor does not form painful metastases in other parts of the body," says De Stasio. The therapy, called Gadolinium Synchrotron Stereotactic Radiotherapy (GdSSR), requires a gadolinium compound to find tumor cells and penetrate them, down into their nuclei, while sparing the normal brain. Then, the patient's head is irradiated with x-rays. For these x-ray photons the whole brain is transparent, while gadolinium is opaque. Then, where gadolinium is localized-in the nuclei of the cancer cells only-what's known as "the photoelectric effect" takes place.

"Exactly 100 years after Einstein first explained this effect, we have found a way to make it useful in medicine," De Stasio says. "In this effect, atoms absorb photons and emit electrons. The emitted electrons are very destructive for DNA, but have
'"/>

Contact: Gelsomina De Stasio
pupa@src.wisc.edu
608-877-2000
University of Wisconsin-Madison
1-Jan-2006


Page: 1 2 3

Related medicine news :

1. Radiotherapy improves 15-year survival after breast-conserving surgery (lumpectomy)
2. Survival differences by race most apparent in advanced stages of breast cancer
3. New drug shows promise in treatment of advanced thyroid cancer
4. Study finds difference in survival rates among white and black women with advanced breast cancer
5. Antidepressant does not improve symptoms in advanced cancer patients without major depression
6. GSKs Pazopanib shows positive results in patients with advanced renal cell carcinoma
7. GSKs Pazopanib shows positive results in patients with advanced RCC and ovarian cancer
8. VEGF Trap shows activity in patients with advanced ovarian cancer
9. Doctors conclude temsirolimus is effective new treatment for advanced renal cell carcinoma
10. Endoscopic procedures advance physician knowledge and patient care
11. Brain research poised to dramatically advance global society

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/14/2019)... ... August 13, 2019 , ... Dr. Rachel Reyes-Bergano, ... network. , The Haute Beauty Network, well known for its exclusive and luxurious ... aesthetic medicine expert and our newest addition to the Haute Beauty members-only network. ...
(Date:8/14/2019)... ... 2019 , ... Today, consumers are taking a harder look at what goes ... emotions and energy levels. The trick is finding food and beverages that are delicious ... founder Chris Harper created Chase – a delicious, guilt free cocktail mixer ...
(Date:8/12/2019)... ... 12, 2019 , ... Ziegler, a specialty investment bank, is ... Lesley University, which is currently rated A-/Stable through S&P. Issued through the Massachusetts ... to refund the outstanding debt on the Series 2011 bonds, the Series 2012 ...
(Date:8/9/2019)... ... August 09, 2019 , ... Advanced Clinical, ... global expansion into Europe’s third largest pharmaceutical market with the recent opening of ... into Italy now completes the organization’s thorough coverage of Western Europe. Access to ...
(Date:8/9/2019)... ... August 08, 2019 , ... Guruji ... today’s issues affecting humanity at practical and spiritual levels. , Founder of ... connection to the God of their understanding, as well as, to illuminate the ...
Breaking Medicine News(10 mins):
(Date:8/15/2019)... , ... August 15, 2019 , ... ... Private Client service for intended parents who are looking for egg donors, gestational ... patients who are looking for the ultimate concierge service and hands-on help in ...
(Date:8/14/2019)... ... August 14, 2019 , ... Canyon State ... 5,217 sf. With pet care at the forefront of design, the project includes ... and CT. Twelve exam rooms, office space and a dedicated grieving space round ...
(Date:8/14/2019)... ... August 13, 2019 , ... ... to approve a BETA version of the NCPDP Real-Time Prescription Benefit (RTPB) Standard. ... signaling strong support for the Standard from across the industry, with representation from ...
Breaking Medicine Technology:
Cached News: