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Rats' response to 'stop snacking' signal diminished by high fat diet

f the time they received either low fat or high fat rat chow. The high and low fat chows were regulated so that they were equivalent in calories and both groups of rats gained weight at the same rate.

Even though the rats on the high fat diet ate, on average 40 percent more of the high calorie, high fat snack than the rats on the low fat diet, they didn't gain extra weight. Rats, unlike humans, cut back on their usual chow when they snack.

Covasa says, "Rats are notorious in compensating for food to maintain a constant body weight. Although adaptation to the high fat diet led to overconsumption of the high calorie, high fat snack, there was no difference in weight gain between the two groups of rats during the 20 days of testing because the rats compensated by eating less of their maintenance diet."


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Contact: Barbara Hale
bah@psu.edu
814-865-9481
Penn State
2-Aug-2005


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