Reduced dietary fat intake may decrease breast cancer ...( ) compared with 51 g/day (29.2% of tota...),Health

) compared with 51 g/day (29.2% of total calories) in the control group. The difference between the two groups was maintained throughout the trial. Average body weight was similar before the trial started, but 5 years later, the women in the intervention group weighed an average of 6 pounds less than the women in the control group.

Ninety-six of 975 women (9.8%) in the intervention group had some form of relapse, compared with 181 of 1462 women (12.4%) in the control group. The researchers calculate that 38 women would need to adopt such a dietary fat reduction plan to prevent one breast cancer recurrence. "Women in the dietary intervention group had a 24% lower risk of relapse than those in the control group," the authors write.

Their data also suggest that women with hormone receptornegative breast cancers may have had the most benefit from the dietary fat reduction, but those results werent statistically significant and will require further confirmation. The authors plan to address these and other questions in ongoing follow-up studies of the women.

They caution that the study relied on self-reports of dietary fat intake. Also, the reduction in body weight in the dietary intervention group may have had an effect on breast cancer recurrence, rather than dietary fat intake on its own.

"The WINS results indicate that a lifestyle intervention designed to reduce dietary fat intake can be successfully implemented in women with early-stage, resected breast cancer receiving conventional cancer management in a multicenter clinical trial setting," the authors write.

In an editorial, Anne C.M. Thiebaut, Victor Kipnis, and colleagues at the National Cancer Institute highlight the studys limitations and note the questions that it raises. They also point out the difficulty of conducting clinical trials of such drastic lifestyle changes. "WINS demonstrates that such trials can be successfully conducted The totality of this ev
'"/>

Contact: Andrea Widener
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
16-Dec-2006

Page: 1 2 3
Related medicine news :

1. Reduced greenhouse gas emissions required to avoid dangerous increases in heat stress
2. Reduced antibiotic prescribing is associated with increased hospital admissions
3. Reduced insulin in the brain triggers Alzheimers degeneration
4. Reduced brain volume may predict dementia in healthy elderly people
5. The dietary history locked up in strands of hair can help diagnose eating disorders
6. Mega-brands have mega influence on dietary behavior
7. National study finds no effect from reducing total dietary fat
8. NHLBI media availability: Low-fat dietary pattern and weight change
9. High intake of dietary fiber not associated with reduced risk of colorectal cancer
10. NIH grant to fund U-Georgias doctoral students innovative dietary research
11. Intake of dietary copper helps Alzheimers patients