Repeat corticosteroids for pregnant women at risk of preterm delivery could be beneficial

Giving pregnant women at risk of preterm delivery repeat doses of corticosteroids* can reduce illness in their newborn babies, suggest the results of an early trial in this week's issue of The Lancet.

Premature babies have a high risk of lung disease and breathing difficulties (respiratory distress syndrome). A single course of corticosteroids before premature delivery is the most effective known strategy of reducing respiratory illness in these babies. Some previous studies suggest that repeating the dose of prenatal corticosteroids may be beneficial for babies but others have reported adverse side effects, including growth problems, infection after birth, and abnormal development in childhood.

To investigate the effectiveness and safety of repeat corticosteroids, Caroline Crowther (Women's and Children's Hospital, North Adelaide, SA, Australia) and colleagues recruited 982 pregnant women at risk of preterm birth into their trial. The women were less than 32 weeks pregnant and had received a single dose of corticosteroids 7 or more days before. The team randomly assigned participants to receive a repeat injection of corticosteroids or a placebo every week until 32 weeks of pregnancy, if they remained at risk of a preterm birth. The researchers followed-up the babies until discharge from hospital and found that fewer babies had respiratory distress syndrome (186 vs 239 / 33% vs 41%) or severe lung disease (65 vs 114 / 12% vs 20%) in the repeat corticosteroids group than in the placebo group. Babies exposed to repeat corticosteroids also needed less oxygen therapy and help breathing. The investigators did not find any difference in the weight, length, and head circumference of the babies in the two treatment groups.

Professor Crowther states: "These short-term benefits for the babies in our study support the use of repeat doses of corticosteroids in women who remain at risk of very preterm birth 7 or more days after an initial course." The au

Contact: Joe Santangelo

Page: 1 2

Related medicine news :

1. Repeat bone mineral density scans do not appear helpful for predicting fractures in most older women
2. How sweet it isnt: Repeat episodes of low blood sugar spell diabetic disaster
3. Bronchial thermoplasty may allow severe asthma patients to wean off oral corticosteroids
4. Inhaled corticosteroids reduce death in patients with COPD
5. Inhaled corticosteroids are better than sodium cromoglycate in asthma control
6. Patients prescribed long-term corticosteroids often do not receive therapy to prevent osteoporosis
7. HIV and malaria combine to adversely affect pregnant women and their infants
8. Increased risk of stillbirth in older pregnant women
9. Precautionary approach suggested to protect pregnant women and children against industrial chemicals
10. Researchers reveal how air pollutant helps pregnant women with hypertension
11. Two-thirds of pregnant women with depression arent getting treatment for it

Post Your Comments:

(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., ... in the United States, today announced the grand opening of another affiliated ... Patients will enjoy convenient hours, a comfortable office, and full-service care at the ...
(Date:8/31/2020)... ... August 31, 2020 , ... Dr. Chang has over 20 ... and other developmental disabilities, as well as supporting staff in caring for patients ... school consultation, and staff development. She joined the company in 2015 as Chief ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... designed to help treat patients with respiratory conditions, including COVID-19, while reducing the ... and oxygen, but it captures exhaled gas and scrubs it free of carbon ...
(Date:8/28/2020)... ... 28, 2020 , ... Ziegler, a specialty investment bank, is ... Synchronous Health, a tech-enabled behavioral health and well-being solutions provider. , Synchronous ... artificial intelligence (AI) to increase access and quality of behavioral health services, and ...
(Date:8/27/2020)... MORRISTOWN, N.J. (PRWEB) , ... August 27, 2020 ... ... has continued to partner with Evolution Labs to provide their students with Suite360:Mental ... issues related to Mental Health, Substance Abuse and Child Trafficking Prevention. , Florida ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... September is National Ovarian Cancer Awareness Month. ... any other cancer of the female reproductive system. The American Cancer Society estimates ... 14,000 women will die from this disease. Throughout the month of September, Women’s ...
(Date:8/31/2020)... ... 31, 2020 , ... Continuing on its rapid national expansion ... and deodorization provider - is proud to announce it has opened doors in ... and residents throughout the area. , Germinator provides a 100% safe and non-toxic ...
(Date:8/28/2020)... ANGELES (PRWEB) , ... August 28, 2020 , ... ... board-certified reproductive and endoscopic surgeon and serves as a clinical professor in the Department ... President of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a ...
Breaking Medicine Technology:
Cached News: