HOME >> MEDICINE >> NEWS
Research shows survival benefit for leukemia patients treated with arsenic trioxide

WINSTON-SALEM, N.C. -- Through participation in a government-sponsored multi-year study, researchers at the Comprehensive Cancer Center at Wake Forest University have helped confirm that arsenic trioxide marketed as Trisenox significantly improves patient survival when coupled with standard chemotherapy treatment in newly diagnosed patients with acute promyelocytic leukemia, or APL.

Bayard Powell, M.D., principal investigator of the study and professor and section head of Hematology and Oncology at Wake Forest University Baptist Medical Center, presented the findings today at the annual meeting of the American Society of Clinical Oncology (ASCO).

Nearly 600 patients in the U.S. and Canada participated in the phase III study over a six-year period from June 1999 through March 2005. The study was sponsored by the National Cancer Institute (NCI) and led by one of its cooperative groups, the Cancer and Leukemia Group B (CALGB). The Comprehensive Cancer Center at Wake Forest University is a member of CALGB.

Patients receiving the arsenic trioxide had a significantly higher likelihood of remaining disease-free, with longer survival than those receiving standard chemotherapy alone, said Powell. The results are so compelling that we recommend use of arsenic trioxide in first-line treatment of APL.

APL is a cancer of the bone marrow in which cancerous cells eventually crowd out the healthy blood cells needed for the body to function normally.

Karen Shelton, a 58 year-old nurse from Kannapolis, was diagnosed with APL in 2001. Ms. Shelton was offered the opportunity to participate in the arsenic trioxide trial. I was eager to take part in the study. Even if it didnt help me, it might help others, she said. She was one of 26 patients enrolled through Wake Forest Baptist.

In remission for nearly six years, Shelton is an advocate of the therapy. I truly believe chemotherapy put me in remission, but the arseni
'"/>

Contact: Jonnie Rohrer
jrohrer@wfubmc.edu
336-716-6972
Wake Forest University Baptist Medical Center
4-Jun-2007


Page: 1 2

Related medicine news :

1. Researchers suggest TB screening for all international adoptees
2. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
3. Researchers link metal ions to neurodegenerative disease
4. RAND presents first Victor Fuchs Research Award to economists at Carnegie Mellon University
5. Wesley Research Institute study targets pharmacists to help diabetes sufferers
6. Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases
7. Research probes seniors plans for end-of-life care
8. DFG approves 11 new Collaborative Research Centers
9. Researchers call for investigation into links between khat use and psychiatric disorders
10. Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research
11. Researcher says few families report safe firearm storage

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology:
Cached News: