Research suggests that immune response protects against brain tumor development

they compared medical histories of 830 brain tumor patients matched to a control group of 831 individuals. Within the patient group were 339 cases of glioblastoma (GBM), the most aggressive and lethal type of brain tumor, as well as 117 cases of midgrade anaplastic astrocytoma (AA) and 154 cases of low-grade gliomas (LGG).

The research team considered recent studies that suggest immune system activity in the brain may protect against brain tumor development and that people who have allergies or asthma have a reduced risk of developing a glioma.

"It could be that allergies and asthma produce enough inflammation in the brain to keep immune system cells active, and that this surveillance works to eliminate cancer beginning to develop in the brain," Scheurer says. "So we wondered whether use of antihistamines that counter that inflammation eliminates the protective effect."

They found that, indeed, a history of allergies and asthma was significantly protective for the three different kinds of brain tumors examined in the study. Individuals with the disorders had a 35 percent reduced risk of developing GBM, a 51 percent reduced risk of AA, and a 36 percent reduced risk of LGG.

They also found that participants who used antihistamines were more likely to develop brain tumors. Participants who used antihistamines had three times the risk of developing an AA tumor and two times the risk of developing LGG, compared to those who did not use antihistamines. The risk of developing a GBM was also increased by 26 percent, but that was not statistically significant, the researchers say.

"This suggests that among people who are susceptible, those who have allergies and don't do anything about it may be protected to some degree against brain tumors," Bondy says. "But those who use antihistamines could decrease that protection and increase their risk. The real question is if there are particular gene variants that would make a person susceptib


Page: 1 2 3

Related medicine news :

1. Researchers suggest TB screening for all international adoptees
2. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
3. Researchers link metal ions to neurodegenerative disease
4. RAND presents first Victor Fuchs Research Award to economists at Carnegie Mellon University
5. Wesley Research Institute study targets pharmacists to help diabetes sufferers
6. Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases
7. Research probes seniors plans for end-of-life care
8. DFG approves 11 new Collaborative Research Centers
9. Research shows survival benefit for leukemia patients treated with arsenic trioxide
10. Researchers call for investigation into links between khat use and psychiatric disorders
11. Tony Hunter receives Robert. J. and Claire Pasarow Award for Cancer Research

Post Your Comments:

(Date:2/14/2020)... ... February 14, 2020 , ... The Dr. Oz Show ... has segments on health, wellness and medical information. As an upcoming guest on the ... Linkov, will be sharing his in-depth medical knowledge. During the segment, Dr. Linkov, a ...
(Date:2/13/2020)... ... February 13, 2020 , ... ... Encanto Palms Assisted Living in Phoenix, AZ announced today his re-election as the ... and Assisted Living Facility Managers (NCIA). , As President of the State ...
(Date:2/11/2020)... (PRWEB) , ... February 11, 2020 , ... There are ... Benefit Management (RBM), but the service that truly raises us above our competitors is ... medical director is a board-certified Radiologist with years of clinical experience. We understand that ...
(Date:2/11/2020)... ... 11, 2020 , ... This week marks the launch of ... Butchery, Mindful Meat Eating for the Modern Omnivore . Authored by nationally-recognized butcher ... version brings discussions of responsible meat production, consumption, and economics into the year ...
(Date:2/10/2020)... ... February 10, 2020 , ... C. A. Shively officially ... At the time he was still in the music business as a majority label ... to create marketing campaigns for HNF, and HNF to create any music compositions needed ...
Breaking Medicine News(10 mins):
(Date:2/13/2020)... LOS ANGELES (PRWEB) , ... February 13, 2020 , ... ... if one is medically obese and how to combat obesity using a multifaceted approach. ... completely valid, they entirely ignore the fact that, when it comes to diet, cutting ...
(Date:2/13/2020)... (PRWEB) , ... February 13, 2020 , ... Results of ... show that they are maintaining a generally positive outlook on the state of ... , Asked if they are better off today than a year ago, 43% said ...
(Date:2/11/2020)... COUNTY, Calif. (PRWEB) , ... February 11, 2020 ... ... people in first aid and other safety measures, is offering courses for hospital ... safety training is a requirement for medical practitioners like nurses, doctors, and other ...
Breaking Medicine Technology:
Cached News: