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Researchers investigate impact of lifestyle on GI health

se Subjects (Abstract #S2191)

Many people believe that ordering an appetizer can actually make you hungrier and that you tend to eat more of your entre as a result. However, researchers from the University of Texas Medical Branch in Galveston, Texas, feel that what you order as a starter determines your overall appetite, as absorption of fat in the small intestine induces the feeling of being full and slows down gastric emptying. The aim of this study was to investigate whether a fatty soup consumed before a meal might reduce food intake in both lean and obese subjects and whether this possible inhibitory effect would be related to changes in gastric functions.

For the study, investigators recruited 12 lean and 12 obese healthy subjects and invited each group to the lab for two sessions (eating both fatty soup and protein soup with the same number of calories and volume). Each session consisted of a 30-minute baseline of soup consumption, a 20-minute post-soup period, an "all you can eat" pizza meal, and a 60-minute post-meal period. Electrogastrogram (a test recording the electrical activity of the stomach, EGG) and electrocardiogram (a similar test recording electrical activity of the heart, ECG) were recorded during each session. Food intake was assessed by the caloric count of the consumed pizza. Several symptoms, including satiety, appetite and nausea, were rated at different times of the study. In a second study, subjects were given the soup appetizer and then taken to an "all-you-can-eat" pizza buffet together in a social setting.

When compared with the protein soup, the fatty soup significantly reduced the amount of caloric intake with the following meal in both lean (962.0 vs. 1,188.5 calories) and obese (1,331.9 vs. 1,544.6 calories) subjects. A similar reduction in caloric intake was noted in lean subjects eating in the social setting (1,555 vs. 1,825 calories), except that significantly more food was consumed in
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Contact: Aimee Frank
AFrank@gastro.org
301-941-2620
American Gastroenterological Association
21-May-2007


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