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Researchers open door to potential treatments for type 2 diabetes

the CIHR Institute of Nutrition, Metabolism and Diabetes.

"By inhibiting the activity of SHP-1, it would perhaps be possible to restore better control of blood glucose," suggests professor Marette. The difficulty, however, is to reach that point without blocking the essential part played by this protein in the immune system. The SHP-1 protein is present in humans, but its role in the regulation of the metabolism of glucose and in the development of Type 2 Diabetes remains to be shown.

"Good glucose control is essential for managing diabetes and preventing the debilitating complications associated with diabetes," says Dr. Paula Dworatzek, Senior Research Associate, Canadian Diabetes Association. "We congratulate Dr. Marette and his team for these initial findings, which will pave the way for his team and others to pursue a potential new therapy in the management of diabetes."


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Contact: Jasmine Sharma
jsharma@cihr-irsc.gc.ca
613-941-0688
Canadian Institutes of Health Research
29-May-2006


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