HOME >> MEDICINE >> NEWS
Researchers study multi-purpose drug

Researchers at the University of Rochester Medical Center today announced that they have launched a study to determine whether an experimental drug, rimonabant, can slow atherosclerosis, the fatty build-up in arteries that creates heart attack risk. In recent studies, rimonabant has been shown to decrease body weight, improve abnormal levels of blood sugars and fats (cholesterol) and to help willing patients quit smoking. Now researchers hope to add coronary artery disease (CAD), atherosclerosis within the arteries of the heart, to the list of maladies addressed. A decision on whether rimonabant is safe and effective and if so, for which uses, is expected from the U.S. Food and Drug Administration in 2006.

Unlike previous cholesterol drugs that treat some aspect of blood or blood vessel walls, rimonabant is a cannabinoid receptor antagonist, which exerts its effect in parts of the brain that control appetite and addictive behaviors. Results of previous studies show that rimonabant reduces triglycerides and increases HDL-C, or "good" cholesterol, independent of weight loss. The new study, titled STADIVARIUS (Strategy to Reduce Atherosclerosis Development Involving Administration of Rimonabant- The Intravascular Ultrasound Study), will explore whether these effects will impact the progression of atherosclerosis.

"Obesity, diabetes, high cholesterol and coronary artery disease have all reached epidemic proportions to become leading causes of death despite being largely preventable," said Frederick S. Ling, M.D., director of the Cardiac Catheterization Laboratory, associate professor of Medicine at the medical center and principal investigator for STRADIVARIUS. "These risk factors, called metabolic syndrome when combined in one person, feed off each other and are made much worse by smoking. New approaches are urgently needed, and our lab has the tools to measure accurately whether new treatments actually slow the progression of coronary artery diseas
'"/>

Contact: Greg Williams
Greg_Williams@urmc.rochester.edu
University of Rochester Medical Center
1-Feb-2006


Page: 1 2

Related medicine news :

1. Researchers suggest TB screening for all international adoptees
2. Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
3. Researchers link metal ions to neurodegenerative disease
4. Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases
5. Researchers call for investigation into links between khat use and psychiatric disorders
6. Researchers use MRI to predict recovery after spinal cord injury
7. Researchers find deadly prescription drug effects 6 years before FDA
8. Researchers investigate impact of lifestyle on GI health
9. Researchers begin randomized double-blind trial of airway bypass treatment for emphysema
10. Researchers discover how antibiotic inhibits bacterial growth
11. Researchers urge caution in using ESAs for cancer-related anemia

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers study multi purpose drug

(Date:3/31/2015)... Dr. St. Ledger recently returned from yet another trip ... Here, he participated in the Worn Dentition Workshop: a ... in cases of severely worn teeth, as well as the ... correlation to GERD and Sleep Apnea. , Dr. ... After the workshop he attended, he mentored for three days ...
(Date:3/31/2015)... Dr. Uzma Parvez is having a busy start ... Grand Grounds Presentations at St. Michael’s Medical Center for attending ... The event was attended by a large gathering of ... feedback from the Grand Rounds. It was said that ... a while. , Ahead, Dr. Parvez has been invited ...
(Date:3/31/2015)... OR (PRWEB) March 31, 2015 Former 49ers ... announcement than during his first year of a promising NFL ... Sports on Earth Senior Writer Will Leitch explores ... the league. Leitch talks about the decision making process that ... the preservation of health over a large paycheck, and what ...
(Date:3/31/2015)... March 31, 2015 Greenfield Senior ... Investment Trust LLC ("Care") a seniors housing-focused real ... Inc. Care announces today, their acquisition of six ... for $54.48 million. Concurrent with the acquisition, Care ... Greenfield Senior Living ("Greenfield"). Pursuant to the lease, ...
(Date:3/31/2015)... Nashville, TN (PRWEB) March 31, 2015 ... 16 countries have united to express their shared support ... living. Part of a 'True Health Coalition' and ... has been formed to help demonstrate that, despite appearances ... among diverse experts worldwide about the theme of healthful ...
Breaking Medicine News(10 mins):Health News:The dentists at Upper Montclair Dental Associates are happy to announce exciting new happenings at their practice. 2Health News:NJ Top Docs Presents, Dr. Uzma Parvez of Total Pain Care 2Health News:Will Leitch and the Curious Case of Chris Borland on SCI TV 2Health News:Will Leitch and the Curious Case of Chris Borland on SCI TV 3Health News:Greenfield Senior Living Inc. Enters Lease Transaction with Care Investment Trust LLC 2Health News:Greenfield Senior Living Inc. Enters Lease Transaction with Care Investment Trust LLC 3Health News:GLiMMER Initiative Founder David Katz, MD Announces the Launch of the True Health Coalition: Worldwide Experts Convened to Defend Fundamentals of Healthy Eating/Living 2Health News:GLiMMER Initiative Founder David Katz, MD Announces the Launch of the True Health Coalition: Worldwide Experts Convened to Defend Fundamentals of Healthy Eating/Living 3Health News:GLiMMER Initiative Founder David Katz, MD Announces the Launch of the True Health Coalition: Worldwide Experts Convened to Defend Fundamentals of Healthy Eating/Living 4
(Date:3/31/2015)... MedSpring Urgent Care is pleased to announce the opening ... area of Upper Greenville. The center – located at 4844 Greenville ... location. Knox - Henderson , its ... since opening last fall. Additional Dallas metroplex ... and Las Colinas neighborhoods this summer. "We ...
(Date:3/31/2015)... , March 31, 2015  InMed Pharmaceuticals Inc. ... biopharmaceutical company that specializes in developing safer, more ... Paul C. Anderson , Ph.D., to its ... industry veteran who brings significant drug discovery and ... is a synthetic organic chemist by training with ...
(Date:3/31/2015)... March 31, 2015  Galmed Pharmaceuticals Ltd. (Nasdaq: ... focused on the development and commercialization of a ... diseases and cholesterol gallstones, today announced financial results ... Fourth Quarter 2014 Highlights: , ... keynote address by Professor Rohit Loomba, MD, MHSc., ...
Breaking Medicine Technology:MedSpring Urgent Care Opens New Upper Greenville Location in Dallas 2InMed Pharmaceuticals Strengthens Scientific Advisory Board 2InMed Pharmaceuticals Strengthens Scientific Advisory Board 3InMed Pharmaceuticals Strengthens Scientific Advisory Board 4Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 2Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 3Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 4Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 5Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 6Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 7Galmed Pharmaceuticals Reports Full Year 2014 Financial Results and Provides Business Update 8
Cached News: