HOME >> MEDICINE >> NEWS
Resistance to anti-flu agents increasing worldwide

Worldwide resistance to drugs used to treat influenza has increased by 12% since the mid-nineties, concludes a report published online today (Thursday September 21, 2005) by THE LANCET.

Adamantanes have been used to treat influenza A virus infections for more than 30 years. Previous surveillance studies have identified a low incidence of resistance to amantadine and rimantadine among circulating influenza virus strains. However, it has been 10 years since the last comprehensive global study of resistance to these drugs was published.

In the largest study of adamantane resistance to date, Rick Bright (Centers for Disease Control and Prevention, Atlanta, GA, USA) and colleagues screened 7000 influenza A isolates for gene mutations known to confer drug resistance. They found that drug resistance increased from 0.4% in 1994-1995 to 12.3% in 2003-2004. They also found that 61% of resistant viruses isolated since 2003 were from people in Asia. Some Asian countries had drug resistance frequencies exceeding 70%.

Dr Bright comments: "We were alarmed to find such a dramatic increase in drug resistance in circulating human influenza viruses in recent years. Our report has broad implications for agencies and governments planning to stockpile these drugs for epidemic and pandemic strains of influenzaWith the increasing rates of resistance shown here, amantadine and rimantadine will probably no longer be effective for treatment or prophylaxis in the event of a pandemic outbreak of influenza." (Quote by e-mail; does not appear in published paper)


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
21-Sep-2005


Page: 1

Related medicine news :

1. Cranberries contain possible anti-caries/anti-plaque agents
2. New contrast agents may be on horizon for better medical imaging
3. New infectious agents pose new risks for people with bleeding disorders, Jefferson hematologist says
4. Use of gastric acid-suppressive agents linked with increased risk for diarrhea infection
5. Program may improve physicians knowledge about diseases caused by bioterrorism agents
6. Gadonanotubes greatly outperform existing MRI contrast agents
7. Possible exposure to nerve agents and brain cancer deaths in Gulf War veterans
8. Herbal medicine may alter cell response to cancer therapeutic agents
9. Penn researchers discover novel pathway for increasing good cholesterol
10. Drugs users are increasingly more cautious with needles
11. Home improvement warning -- Ladder-related injuries increasing in the US

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... transport experience for the millions of people who require these medical transport services ... industry through the use of technology. Now, SmartEMS has put forth an industry-changing ...
(Date:6/26/2016)... ... 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing ... their videos a whole new perspective by using the title layers in ProSlice ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room ... Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. ... of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from PsychTests.com reveals that behind the tendency to set low expectations ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... 23, 2016 Bracket , a leading clinical ... generation clinical outcomes platform, Bracket eCOA (SM) 6.0, at ... 26 – 30, 2016 in Philadelphia , ... Outcome Assessment product of its kind to fully integrate with ... Bracket eCOA 6.0 is a flexible platform for electronic clinical ...
(Date:6/23/2016)... June 23, 2016  Guerbet announced today that it ... Supplier Horizon Award . One of 12 ... recognized for its support of Premier members through exceptional ... excellence, and commitment to lower costs. ... recognition of our outstanding customer service from Premier," says ...
Breaking Medicine Technology:
Cached News: