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Rheumatoid arthritis patients can benefit from Enbrel in combination with methotrexate

eadaches (17%) Malignancies were rare.

Physicians in Europe have become familiar with the benefits and long-term tolerability profile of ENBREL since it became commercially available over six years ago. More than 400,000 patients have been treated worldwide across indications. ENBREL acts by binding tumor necrosis factor (TNF), one of the dominant inflammatory cytokines or regulatory proteins that play an important role in both normal immune function and the cascade of reactions that causes the inflammatory processes of rheumatoid arthritis. The binding of ENBREL to TNF renders the bound TNF biologically inactive, which can result in significant reduction in inflammatory activity.


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Contact: Jes Lauritzen
jes.lauritzen@ketchum.com
44-781-437-7386
Ketchum
22-Jun-2006


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