HOME >> MEDICINE >> NEWS
Risk of heart attack may increase with certain anti-inflammatory drugs

Ibuprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack, says a study in this week's BMJ.

Patients should not stop taking the drugs involved non-steroidal anti-inflammatory drugs (NSAIDS) but further investigation into these treatments is needed, say the authors.

In the biggest study of its kind to date, researchers identified 9,218 patients across England, Scotland and Wales who suffered a heart attack for the first time over a four year period. Patients ranged in age from 25 to 100.

Researchers looked at the prescribing patterns for these patients, tracking whether and when they had been prescribed NSAIDS. NSAIDS are commonly prescribed to relieve inflammation and pain, and include ibuprofen, diclofenac, naproxen, celecoxib and rofecoxib, plus a host of other less commonly prescribed anti-inflammatories.

The findings were adjusted to allow for several other heart attack risk factors including age, obesity, and smoking habits. Importantly, they also adjusted for whether the patient already suffered from heart disease, or whether they were being prescribed aspirin.

Researchers found that for those prescribed NSAIDS in the three months just before the heart attack, the risk increased compared with those who had not taken these drugs in the previous three years. For ibuprofen, the risk increased by almost a quarter (24%), and for diclofenac it rose by over a half (55%).

The newer generation of anti-inflammatories - COX-2 inhibitors - were also associated with increased rates of first-time heart attack. Those prescribed the drugs in the preceeding three months were at 21% higher risk of heart attack if taking celecoxib, and 32% increased risk if taking rofecoxib.

Since this study was concluded rofecoxib has already been withdrawn following concerns over heart attack risk. This is all the more important for the impact of this study on patients, say the
'"/>

Contact: Emma Dickinson
edickinson@bmj.com
44-207-383-6529
BMJ-British Medical Journal
9-Jun-2005


Page: 1 2

Related medicine news :

1. A broader look at cardiac CTA images often finds diseases/disorders beyond the heart
2. Drug for cluster headaches may cause heart problems
3. Reductive stress linked to heart disease
4. Novel candidate biomarker for heart failure also strongly predicts risk of death
5. Many heart attack patients still not getting emergency clot-busting treatment
6. New heart disease risk score will help minimize health inequalities
7. Metabolic syndrome points to heart health
8. Herceptin does not increase heart failure in patients long term
9. Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
10. Mayo researchers discover overdiagnosis of long QT heart syndrome
11. Exercise test may help predict mortality risk in heart failure patients

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Risk heart attack may increase with certain anti inflammatory drugs

(Date:7/22/2014)... Garland’s new Energizer BK specially ... as a flood coat over new and existing asphalt ... restoration material. It provides natural resistance to moisture, chemicals, ... life-cycle costs. Energizer BK is specially formulated with an ... in addition to superior strength and flexibility. , ...
(Date:7/22/2014)... UT (PRWEB) July 22, 2014 Most people encounter ... is a weak appetite and the second is a fast metabolism. ... CB-1 Weight Gainer provides ways to help fight these problems ... of appetite. There are people out there who just can’t seem ... bites and then they are full. The cause of this problem ...
(Date:7/22/2014)... CA (PRWEB) July 22, 2014 The ... training, olympic weightlifting, plyometrics, powerlifting, gymnastics, kettleball lifting, calisthenics, ... workout. , Jason Sobzcak, co-owner of CrossFit ... EnergyFirst’s products because extreme workouts like these require ... Paleo diet so I need to take in about ...
(Date:7/21/2014)... (PRWEB) July 22, 2014 Recently, Stwd.co.uk, a ... of cheap wedding dresses. Additionally, the company’s chief executive officer ... at discounted prices, up to 58% off. , “All our ... The special offer is launched to bring huge benefits to ... collection of cheap wedding outfits. By the way, we offer ...
(Date:7/21/2014)... 2014 PowerObjects, a professional services ... and add-ons for Microsoft Dynamics CRM, has joined ... elite group of the most strategic Microsoft Dynamics ... that rank them in the highest echelon of ... of the Microsoft Dynamics Inner Circle have performed ...
Breaking Medicine News(10 mins):Health News:Energizer® BK Waterproof Coating from Garland Canada Reduces Life-Cycle Costs 2Health News:CB-1 Weight Gainer Provides Two Tips to Help Customers Gain Weight 2Health News:CrossFit East Cobb Fuels Their Intense Workouts with All-Natural EnergyFirst Supplements 2Health News:CrossFit East Cobb Fuels Their Intense Workouts with All-Natural EnergyFirst Supplements 3Health News:2014 Cheap Wedding Dresses, Newest Items Offered by Professional Company Stwd.co.uk 2Health News:PowerObjects Joins the 2014 Microsoft Dynamics Inner Circle 2
(Date:7/21/2014)... , July 21, 2014 McCord Research, ... (U.S. Patent No. 8,796,315). This patent describes a ... healing.  According to the inventor, Dr. McCord, this ... require wound healing, a composition of an effective ... from umbilical cord blood, such that the administration ...
(Date:7/21/2014)... -- Nitrosolution.com, a website that features safe and all-natural ... anniversary in August. The online retailer specializes in an ... ability to produce nitric oxide. Called Nitroxyl, it is ... variety of phytonutrients and other natural ingredients that a ... nitric oxide production in the arteries and brain. ...
(Date:7/21/2014)... , July 21, 2014  Champions Oncology (OTC: ... technology solutions and services to personalize the development and ... its financial and operational results for the fourth quarter ... July 24, 2014, after market close. The ... results that day at 4:30 p.m. EDT (1:30 p.m. ...
Breaking Medicine Technology:US Patent Office Grants McCord Research Endothelial Cell Treatment Patent 2Up and Coming Nitric Oxide Supplements Company Nitrosolution.com Celebrates its One Year Anniversary 2
Cached News: