HOME >> MEDICINE >> NEWS
Risk of heart attack may increase with certain anti-inflammatory drugs

Ibuprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack, says a study in this week's BMJ.

Patients should not stop taking the drugs involved non-steroidal anti-inflammatory drugs (NSAIDS) but further investigation into these treatments is needed, say the authors.

In the biggest study of its kind to date, researchers identified 9,218 patients across England, Scotland and Wales who suffered a heart attack for the first time over a four year period. Patients ranged in age from 25 to 100.

Researchers looked at the prescribing patterns for these patients, tracking whether and when they had been prescribed NSAIDS. NSAIDS are commonly prescribed to relieve inflammation and pain, and include ibuprofen, diclofenac, naproxen, celecoxib and rofecoxib, plus a host of other less commonly prescribed anti-inflammatories.

The findings were adjusted to allow for several other heart attack risk factors including age, obesity, and smoking habits. Importantly, they also adjusted for whether the patient already suffered from heart disease, or whether they were being prescribed aspirin.

Researchers found that for those prescribed NSAIDS in the three months just before the heart attack, the risk increased compared with those who had not taken these drugs in the previous three years. For ibuprofen, the risk increased by almost a quarter (24%), and for diclofenac it rose by over a half (55%).

The newer generation of anti-inflammatories - COX-2 inhibitors - were also associated with increased rates of first-time heart attack. Those prescribed the drugs in the preceeding three months were at 21% higher risk of heart attack if taking celecoxib, and 32% increased risk if taking rofecoxib.

Since this study was concluded rofecoxib has already been withdrawn following concerns over heart attack risk. This is all the more important for the impact of this study on patients, say the
'"/>

Contact: Emma Dickinson
edickinson@bmj.com
44-207-383-6529
BMJ-British Medical Journal
9-Jun-2005


Page: 1 2

Related medicine news :

1. A broader look at cardiac CTA images often finds diseases/disorders beyond the heart
2. Drug for cluster headaches may cause heart problems
3. Reductive stress linked to heart disease
4. Novel candidate biomarker for heart failure also strongly predicts risk of death
5. Many heart attack patients still not getting emergency clot-busting treatment
6. New heart disease risk score will help minimize health inequalities
7. Metabolic syndrome points to heart health
8. Herceptin does not increase heart failure in patients long term
9. Fat protein cuts blood vessel inflammation, may help heart, Jefferson scientists find
10. Mayo researchers discover overdiagnosis of long QT heart syndrome
11. Exercise test may help predict mortality risk in heart failure patients

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Risk heart attack may increase with certain anti inflammatory drugs

(Date:9/4/2015)... ... September 04, 2015 , ... Mike Day, a former Navy SEAL ... in the Ironman World Championships in Kona on October 10th. , Mike is running ... Injury (TBI) through combat and the cutting-edge treatments that restore their quality of life. ...
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... The USC ... was ranked number 9 nationwide by Doximity. Faculty, residents and staff are honored ... great pride in the quality of our ophthalmology residency program. Our faculty places a ...
(Date:9/4/2015)... (PRWEB) , ... September 04, 2015 , ... ... and development of its first neighborhood created specifically for adults with intellectual, developmental ... the Phoenix Metro area and feature 30 cottage or “pocket” homes. In this ...
(Date:9/4/2015)... DC (PRWEB) , ... September 04, 2015 , ... ... they all pale in comparison to settlements under the Stark physician self-referral law. ... an upcoming Sept. 17 webinar from Atlantic Information Services, Inc. (AIS), will detail ...
(Date:9/4/2015)... ... September 04, 2015 , ... ... company today announced that it has entered into a multi-year agreement with Health ... agreement to bridge the link between American healthcare, Jamaican healthcare and Health City ...
Breaking Medicine News(10 mins):Health News:Navy SEAL Shot 27 Times Competes in Ironman World Championship in Kona to Raise Money for Veteran's Suffering from TBI and PTSD 2Health News:USC Ophthalmology Residency Program Ranked in Top 10 by Doximity 2Health News:USC Ophthalmology Residency Program Ranked in Top 10 by Doximity 3Health News:Cottage Home Communities for Disabled Adults to Create First Viable Permanent Housing Option 2Health News:Cottage Home Communities for Disabled Adults to Create First Viable Permanent Housing Option 3Health News:Cottage Home Communities for Disabled Adults to Create First Viable Permanent Housing Option 4Health News:Sept. 17 Webinar to Offer Best Practices for Physician Contracts 2Health News:EMED Agreement with Health City Cayman Islands Provides for Up to 80% Savings for Patients in Need of Medical Procedures 2Health News:EMED Agreement with Health City Cayman Islands Provides for Up to 80% Savings for Patients in Need of Medical Procedures 3Health News:EMED Agreement with Health City Cayman Islands Provides for Up to 80% Savings for Patients in Need of Medical Procedures 4Health News:EMED Agreement with Health City Cayman Islands Provides for Up to 80% Savings for Patients in Need of Medical Procedures 5Health News:EMED Agreement with Health City Cayman Islands Provides for Up to 80% Savings for Patients in Need of Medical Procedures 6
(Date:9/4/2015)... , Sep. 04, 2015 ... the addition of the "Stability Testing of Pharmaceuticals ... their offering. By attending this comprehensive two ... to design efficient stability studies that are suitable for ... appropriate stability studies and manage stability samples and facilities ...
(Date:9/4/2015)... , September 4, 2015 ... today announces that Hutchison MediPharma Limited ("HMP"), its ... in the second proof-of-concept ("POC") trial of fruquintinib ... cancer ("NSCLC") in China . ... succeeded in meeting the primary efficacy endpoint of ...
(Date:9/3/2015)... , Sept. 3, 2015 Report ... market? Which areas are going to grow at the ... revenues to 2025, assessing data, trends, opportunities and prospects ... charts, and graphs. Discover the most lucrative areas in ... study lets you assess forecasted sales at overall world ...
Breaking Medicine Technology:Stability Testing of Pharmaceuticals: 2 Day Seminar - London, UK - December 2-3, 2015 2Second Proof-of-concept Trial of Fruquintinib Achieves its Primary Endpoint 2Second Proof-of-concept Trial of Fruquintinib Achieves its Primary Endpoint 3Ophthalmic Devices Market Forecast 2015-2025: Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 2Ophthalmic Devices Market Forecast 2015-2025: Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 3Ophthalmic Devices Market Forecast 2015-2025: Future Prospects for Leading Companies in Vision Care, Surgical, Diagnostic & Monitoring Devices 4
Cached News: