HOME >> MEDICINE >> NEWS
Scent prediction

This release is also available in German.

The scent of lily of the valley hangs in the air for readers of the journal Angewandte Chemie: just rub the journal's cover and enjoy a lily-of-the-valley scent. Lily-of-the-valley scent components can also be found within the pages of the journal: an interdisciplinary team headed by Reinhold Tacke (Inorganic Chemistry, University of Wrzburg), Philip Kraft (Scent Research, Givaudan Schweiz Inc.), and Hanns Hatt (Cell Biology, University of Bochum) have attempted a "scent prediction" to test their computer model of lily-of-the-valley fragrance receptor hOR17-4. This molecule was characterized in detail as the first human scent receptor by Hatt and his co-workers, who also discovered it in sperm.

A fragrance is usually composed of a mixture of many different scented substances. Each of these individual substances can react with several of the approximately 347 scent receptors in our nose and show a complex scent. "When developing new fragrances, we have to rely on correlations between structure and effect derived from model substances as well as intuition," says Kraft. With the help of sperm, however, it is possible to study the lily-of-the-valley receptor in virtual isolation and simulate the primary process of scent sensing by computer.

An olfactory receptor responds to a scent molecule when it fits into the receptor's binding cavity. If the structure of the cavity is known, it should be possible to use computer models to predict whether a scent activates the receptor in question and to what degree. To prove this theory, the scientists investigated how the replacement of one carbon atom with a silicon atom affects the scent of lily-of-the-valley fragrance components lilial and bourgeonal, and whether this subtle alteration, which has minimal influence on the molecular shape, can also be predicted quantitatively. The
'"/>

Contact: Reinhold Tacke
r.tacke@mail.uni-wuerzburg.de
49-931-888-5250
John Wiley & Sons, Inc.
18-Apr-2007


Page: 1 2

Related medicine news :

1. Scent of fear impacts cognitive performance
2. Newer biomarkers add small improvement in cardiovascular risk prediction to established risk factors
3. Genomic tests improve prediction of breast cancer response to chemotherapy, hormonal therapy
4. Hopkins researchers identify risk factors for prediction of lethal prostate cancer after recurrence

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scent prediction

(Date:12/17/2014)... parents should leave prenatal picture-taking to medical professionals, the ... ultrasound imaging and heartbeat monitors to get "keepsake" images ... "Although there is a lack of evidence ... monitors, prudent use of these devices by trained health ... engineer, said in an agency news release. "Ultrasound ...
(Date:12/17/2014)... Mozes HealthDay Reporter TUESDAY, ... season fast approaching, a new study reveals that states that ... fewer drunk drivers on their roads. The finding suggests ... better able to deter inebriated revelers from getting behind the ... are being passed regarding drinking and driving," said study lead ...
(Date:12/15/2014)... Grants Pass, OR (PRWEB) December 15, 2014 ... factors perceived by United States women as impacting skin ... – the “Four C’s of skin care.” Water and ... the conclusions in a recent article describing the survey ... her experience, every item in every category discussed would ...
(Date:12/15/2014)... 15, 2014 Main Street Dental Team ... weighing in on a new study providing evidence on ... oral hygiene of children. , Sufficient enough evidence already ... as pop or juice drinks, with the onset of ... is whether drinks listed as 100% fruit juice, meaning ...
(Date:12/15/2014)... OutMarket , a provider of ... Media Cheat Sheets ,” a guide that exposes the ... on the top ten social media networks. , ... awareness, engagement, and customer service. It can also increase ... impact on new networks and weather constantly changing algorithms, ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 2Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 3Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 3Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Comments on New Study Relating Pure Fruit Juice to Poor Oral Hygiene 2Health News:OutMarket Releases Cheat Sheets for Social Media Marketing 2Health News:OutMarket Releases Cheat Sheets for Social Media Marketing 3
(Date:12/17/2014)... , Dec. 17, 2014  IGI Laboratories, Inc. ... the closing of its offering of $125 million aggregate ... (the "Notes").  The Notes were offered and sold only ... the Securities Act of 1933, as amended (the "Securities ... fixed rate of 3.75% per year, payable semiannually in ...
(Date:12/17/2014)... Dec. 17, 2014 PCCA received the ... ( http://bit.ly/1382OkS ) program seal for best practices ... program highlights medical practices, materials and goods that ... Children affected by autism often have ... exacerbated by ingredients found in food and medicine ...
(Date:12/15/2014)... and Markets ( http://www.researchandmarkets.com/research/bf3b6l/electrocardiogram ) has announced ... Global Trends, Estimates and Forecasts, 2012-2018" report to ... Global Electrocardiogram Devices (ECG) sector is projected ... North America accounts for nearly 36% (2015) ... claims approximately 27% (2018). Asia-Pacific ...
Breaking Medicine Technology:IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4
Cached News: