HOME >> MEDICINE >> NEWS
Scientists identify cells responsible for relapse after treatment in common childhood cancer

Approximately 20% of children with ALL will experience a relapse of their disease following treatment. Of these, most will never be cured.

"We have previously shown that these relapses were due to small numbers of cells which survived the treatment administered to the patient," said Prof Norris.

"However, it has been unclear whether these cells developed resistance to chemotherapy during the course of treatment or if they were already present in the child at the time their cancer was diagnosed."

The findings of this study demonstrate that relapse in ALL patients can result from a minor, but intrinsically resistant subpopulation of cells, present from the time of diagnosis. Undetected at diagnosis because of their very small numbers, this population of leukaemia cells remained in the patients body throughout the disease and continued to thrive even after the major population of sensitive leukaemia cells were destroyed and the patient appeared to have gone into remission.

"We have shown, for the first time, that children with a greater number of these cells at diagnosis are more likely to experience relapse much sooner after treatment.

"Without new strategies to identify and attack these cells early in treatment, relapse appears inevitable for these patients," said Prof Norris.

"Our ability to characterise these cells means that researchers can now develop treatments which specifically target the cells and are more effective than current options."


'"/>

Contact: Pearly Harumal
61-293-828-823
Research Australia
29-Mar-2007


Page: 1

Related medicine news :

1. Scientists train nano-building blocks to take on new shapes, as reported in Science
2. Scientists find war vets hand dexterity determines susceptibility to PTSD
3. Scientists develop method to track immune system enzyme in live animals
4. Scientists from the CIMA investigate a molecule for diagnosing hypertensive cardiopathy
5. Scientists equip bacteria with custom chemo-navigational system
6. Scientists find missing link to understand how plants make vitamin C
7. Scientists and polar explorers brave the elements in support of CryoSat-2
8. Scientists progress in successful tissue engineering
9. Scientists re-grow dental enamel from cultured cells
10. Scientists create dual-modality microbeads to improve identification of disease biomarkers
11. Scientists develop method to remove prion infectivity from scrapie-infected blood

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/19/2017)... , ... September 19, 2017 , ... ... the addition of strategic marketing leader, Denise Flannery, to its strategic advisory and ... and Management Consultant, Denise will work with clients across different industries to develop ...
(Date:9/19/2017)... TX (PRWEB) , ... September 19, 2017 , ... ... non-profit organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma ... – will return to Texas as a part of its national Swirl: A ...
(Date:9/19/2017)... Chevy Chase, MD (PRWEB) , ... September 19, ... ... last week, the Society of Professional Benefit Administrators (SPBA) hosted “Expanding ... learning opportunities for SPBA Members as it focused on best practices for third ...
(Date:9/19/2017)... ... September 19, 2017 , ... Big Barker ... for its September 2016 donation of dog beds to the K9 officers of ... and honors for its contribution from city and state officials. , The ...
(Date:9/19/2017)... ... ... The ISO 9001 standard sets out the requirements for a quality management ... customer satisfaction. ISO 9001:2015 was released in 2015 and certified organizations have three years ... , As described in this white paper , ISO 9001:2015 places ...
Breaking Medicine News(10 mins):
(Date:9/7/2017)... Texas , Sept. 7, 2017 ... science focused on fulfilling the promise of precision ... further validate the benefits of its molecular profiling ... study utilized comprehensive genomic profiling plus (CGP+) with ... individual patient,s tumor on a molecular level, leading ...
(Date:9/6/2017)...  Medical professionals are expected to continuously ... their patients. Medical simulations offer clinicians the ... Simulation provides a safe method for teaching ... refine techniques and build confidence, without putting ... such as augmented reality, will now provide ...
(Date:9/5/2017)... has announced another milestone in their continued growth and success of the company.  ... of customer engagements regionally.  ... is located at 318 West Adams Street, Suite 1528, Chicago, IL ... Xyntek's recently opened Midwest office will ... In addition to ...
Breaking Medicine Technology:
Cached News: