HOME >> MEDICINE >> NEWS
Scientists identify cells responsible for relapse after treatment in common childhood cancer

Approximately 20% of children with ALL will experience a relapse of their disease following treatment. Of these, most will never be cured.

"We have previously shown that these relapses were due to small numbers of cells which survived the treatment administered to the patient," said Prof Norris.

"However, it has been unclear whether these cells developed resistance to chemotherapy during the course of treatment or if they were already present in the child at the time their cancer was diagnosed."

The findings of this study demonstrate that relapse in ALL patients can result from a minor, but intrinsically resistant subpopulation of cells, present from the time of diagnosis. Undetected at diagnosis because of their very small numbers, this population of leukaemia cells remained in the patients body throughout the disease and continued to thrive even after the major population of sensitive leukaemia cells were destroyed and the patient appeared to have gone into remission.

"We have shown, for the first time, that children with a greater number of these cells at diagnosis are more likely to experience relapse much sooner after treatment.

"Without new strategies to identify and attack these cells early in treatment, relapse appears inevitable for these patients," said Prof Norris.

"Our ability to characterise these cells means that researchers can now develop treatments which specifically target the cells and are more effective than current options."


'"/>

Contact: Pearly Harumal
61-293-828-823
Research Australia
29-Mar-2007


Page: 1

Related medicine news :

1. Scientists train nano-building blocks to take on new shapes, as reported in Science
2. Scientists find war vets hand dexterity determines susceptibility to PTSD
3. Scientists develop method to track immune system enzyme in live animals
4. Scientists from the CIMA investigate a molecule for diagnosing hypertensive cardiopathy
5. Scientists equip bacteria with custom chemo-navigational system
6. Scientists find missing link to understand how plants make vitamin C
7. Scientists and polar explorers brave the elements in support of CryoSat-2
8. Scientists progress in successful tissue engineering
9. Scientists re-grow dental enamel from cultured cells
10. Scientists create dual-modality microbeads to improve identification of disease biomarkers
11. Scientists develop method to remove prion infectivity from scrapie-infected blood

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2019)... ... November 15, 2019 , ... ... webinar on comprehensive school physical activity programs (CSPAP) on December 3, 2019 at ... recreation and park professionals, this one-hour and 15-minute webinar will discuss the five ...
(Date:11/14/2019)... ... , ... With Giving Tuesday on Dec. 3, 2019, the ... about the benefits of supporting local hospitalized veterans throughout Maryland. Created in 2012, ... to give, collaborate and celebrate generosity before the holidays, and enables participants to ...
(Date:11/14/2019)... ... November 14, 2019 , ... BioInformatics Inc., part of Science and ... today announced that 7 companies have been nominated for a Life Science Industry ... Since 2002, the Life Science Industry Awards have recognized manufacturers of the “tools of ...
(Date:11/12/2019)... Ind. (PRWEB) , ... November 12, 2019 , ... ... a select group of individuals/organizations who have truly impacted those diagnosed with infertility. ... received RESOLVE’s prestigious Hope Award for Achievement, presented at the Night of Hope ...
(Date:11/12/2019)... ... 2019 , ... The quality of study start-up can dictate ... contract negotiations and 80 percent of organizations still using spreadsheets to track activities, ... improvement. Following an overview of the challenges facing trial sponsors, this webinar will ...
Breaking Medicine News(10 mins):
(Date:11/11/2019)... ... November 11, 2019 , ... PRP Science , Florida’s ... is now representing two of the most respected manufacturers in the medical aesthetics arena; ... Ameia Med is the leading developer of the EXCEED micro-needling device ...
(Date:11/11/2019)... ... November 11, 2019 , ... Attorneys representing an ... statement before U.S. Bankruptcy Court Judge Robert Drain in White Plains, NY notifying ... prescription opioid epidemic cannot be forgotten as a $12 billion settlement is considered. ...
(Date:11/11/2019)... ... November 11, 2019 , ... Over 60 schools in the northwest panhandle of ... program is designed to provide virtual mental health care to more than 35,000 students ... in October of 2018 [1]. , “This initiative by the state of Florida,” says ...
Breaking Medicine Technology:
Cached News: