HOME >> MEDICINE >> NEWS
Scientists progress in successful tissue engineering

Tissue engineering is a relatively new field of basic and clinical science that is concerned, in part, with creating tissues that can augment or replace injured, defective, or diseased body parts. The approach to fabricating the tissues involves adding specific cell types to grow on a polymer scaffold having the shape of the tissue to be restored. The scaffold gradually disappears, while the cells continue developing in the scaffold shape. With the use of non-human animal cells, there has been considerable recent progress made in the engineering of skin, bladder, cartilage, and several other tissues.

Today, during the 85th General Session of the International Association for Dental Research, scientists are reporting on experiments applying human cells from cartilage (chondrocytes) on a scaffold. If the chondrocytes could be successfully grown in this manner, they were also interested in determining whether their development could be enhanced by a protein (osteogenic protein-1) that was known to increase production by chondrocytes of a major cartilage extracellular matrix component, proteoglycan. This study had not been undertaken previously.

Experiments were conducted as follows: Normal ankle cartilage was obtained from a deceased adult through the Gift of Hope Organ & Tissue Donor Network in Elmhurst, IL. The chondrocytes from the cartilage were isolated and purified by standard laboratory procedures. They were then applied to small polymer (polyglycolic acid) scaffolds that were disc-shaped. Three such constructs were created for comparison of possible cell growth and proteoglycan production. The first consisted of a scaffold treated with cells only, the second a scaffold with cells to which osteogenic protein-1 (from Stryker Biotech, Hopkinton, MA) was added drop-wise, and the third a scaffold incorporating timed-release capsules of osteogenic protein-1 together with cells. The constructs were maintained for 4 weeks and then analyzed for the presen
'"/>

Contact: Linda Hemphill
lhemphill@iadr.org
International & American Association for Dental Research
23-Mar-2007


Page: 1 2

Related medicine news :

1. Scientists train nano-building blocks to take on new shapes, as reported in Science
2. Scientists find war vets hand dexterity determines susceptibility to PTSD
3. Scientists develop method to track immune system enzyme in live animals
4. Scientists from the CIMA investigate a molecule for diagnosing hypertensive cardiopathy
5. Scientists equip bacteria with custom chemo-navigational system
6. Scientists find missing link to understand how plants make vitamin C
7. Scientists and polar explorers brave the elements in support of CryoSat-2
8. Scientists identify cells responsible for relapse after treatment in common childhood cancer
9. Scientists re-grow dental enamel from cultured cells
10. Scientists create dual-modality microbeads to improve identification of disease biomarkers
11. Scientists develop method to remove prion infectivity from scrapie-infected blood

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/14/2019)... ... January 15, 2019 , ... Jeffery Nelson, M.D., FACS, ... Institute for Digestive Health & Liver Disease at Mercy Medical Center , ... designed instrument known as a suction hemorrhoid ligator is used with the procedure; ...
(Date:1/14/2019)... ... January 14, 2019 , ... Specialty Technical ... updated International Audit Protocol Consortium (IAPC) EHS audit protocol for Great Britain ... the scope of their EHS regulatory obligations and rapidly collect, share, archive, and ...
(Date:1/11/2019)... ... ... In Partnership with the Smiles for Everyone Foundation , Monarch Dental ... TX office on February 9. , Dental services provided include same-day procedures such ... For more information, please visit the Monarch Dental website . , About Monarch ...
(Date:1/10/2019)... ... January 10, 2019 , ... Mount Sinai Health ... Society at the United Nations Staff Recreation Council in support of the Helen ... complementary services including music, art, massage, and pet therapies to increase the comfort ...
(Date:1/10/2019)... ... January 10, 2019 , ... JWRX, a leading source for ... Companion to educate dog owners on CBD and hemp products and provide quality ... and anxiety related ailments by supporting a pet’s endocannabinoid system, which helps regulate ...
Breaking Medicine News(10 mins):
(Date:1/8/2019)... (PRWEB) , ... January 08, 2019 , ... ... have been trending towards wellness-oriented lifestyles for their residents. Now the findings of ... has been reached. , Conducted by the International Council on Active Aging® (ICAA), ...
(Date:1/8/2019)... ... 08, 2019 , ... “A baby is born with a ... that alarming statistic,” said Christina Chambers, PhD, MPH, President of MotherToBaby, a free ... with leading prenatal health experts from the National Birth Defects Prevention Network (NBDPN), ...
(Date:1/7/2019)... CHARLOTTE, N.C. (PRWEB) , ... January 07, 2019 , ... ... early as 12 years old to then vaginal health challenges with age or post-partum ... silence. Even with the rise in social media and public conversations, the world still ...
Breaking Medicine Technology:
Cached News: