Several factors can increase risk for recurrent blood clot

Patients who have a blood clot are at high risk of having another one, and men have more than twice the risk as women, according to a study in the May 18 issue of JAMA.

While estimates of the overall risk of a thrombotic (blood clot) event recurrence vary, reports on contributing factors are contradictory, according to background information in the article. Knowledge of the risk of a thrombotic event recurrence and its determinants is relevant for clinical policy regarding screening for thrombophilia (increased risk for blood clot), duration of anticoagulant treatment, and treatment strategies in circumstances of increased risk.

Sverre C. Christiansen, M.D., of the Leiden University Medical Center, Leiden, the Netherlands, and colleagues conducted a follow-up study of 474 patients aged 18 to 70 years who had a thrombotic event to determine the risk of recurrence and the effect of several thrombophilic risk factors on the risk of recurrence. The Leiden Thrombophilia Study (LETS) was conducted from 1988 through 1992 and patients were followed-up through 2000.

A total of 474 patients were followed up an average of 7.3 years and recurrent thrombotic events occurred in 90 patients. The researchers "found an annual risk of thrombotic event recurrence of 2.6 percent. The cumulative risk of recurrence was 12.4 percent after 5 years and 16.5 percent after 7 years of follow-up. Although the incidence rate was slightly higher in the first 2 years, at an annual rate of 3.2 percent, the risk of thrombotic event recurrence persisted at a high level of more than 2 percent during the following years."

The risk of thrombotic event recurrence was 2.7 times higher in men than in women. Patients whose initial thrombotic event was idiopathic (unknown cause) had nearly two times the risk of a thrombotic event recurrence than patients whose initial event was provoked. Women who used oral contraceptives during follow-up had a higher thrombotic event recur

Contact: Frits R. Rosendaal, M.D., Ph.D.
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Study, meta-analysis examine factors associated with death from heatstroke
3. Parents and schools, major factors in China obesity boom
4. Smoking and sleep top the list of lifestyle factors impacting oral health
5. Reducing cardiovascular disease risk factors when discontinuing hormone replacement therapy
6. Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
7. Having elevated risk factors in young adulthood raises risk of coronary calcium later on
8. USC study identifies factors attributed to later stage cancer diagnosis
9. U of M study identifies factors associated with successful weight loss in teens
10. Diabetes risk factors develop earlier in women than men
11. Growth factors given with chemotherapy associated with increased risk of blood diseases

Post Your Comments:

(Date:2/14/2020)... ... February 14, 2020 , ... Cloudticity announced today ... the company’s support for healthcare organizations using Amazon Web Services (AWS). , “Our ... or experience to do so,” explained Cloudticity Founder & CEO, Gerry Miller. “In ...
(Date:2/13/2020)... (PRWEB) , ... February 13, 2020 , ... ... seven locations in Northern Virginia: Arlington, Dulles-Aldie, Fair Oaks, Fairfax, Fredericksburg, Leesburg, and ... that eight D.C.- and Virginia-based fertility specialists have been named as Top Docs ...
(Date:2/11/2020)... ... 2020 , ... Soterius, Inc., a global provider of cutting-edge ... new, significantly larger business premises in Lawrenceville, NJ. The move supports the requirements ... digital technology platforms. , “As our customer base and offerings continue to grow, ...
(Date:2/10/2020)... ... , ... A January 26 article on Live Science reports on ... that – not unlike the skin’s response to dangerous conditions like extreme heat or ... to potential damage being done and warn the individual to escape the situation. Pasadena-based ...
(Date:2/10/2020)... Md. (PRWEB) , ... February 10, 2020 , ... ... the Public Health and Epidemiology Practice, has been elected president of the ... Group where she and her team develop and implement award-winning, research-driven Federal social ...
Breaking Medicine News(10 mins):
(Date:2/15/2020)... ... February 14, 2020 , ... The creators of Dullo Plus - ... relaxing sleep experience—are excited to announce the launch of a Kickstarter campaign for 35 ... types of pillows over the last four years. Dullo Plus is their most advanced ...
(Date:2/14/2020)... (PRWEB) , ... February 14, 2020 , ... ... donation of $55,496 to Children’s Healthcare of Atlanta (Children’s) raised through their annual ... a portion of all new or pre-owned vehicle sales between November 29, 2019, ...
(Date:2/13/2020)... Va. (PRWEB) , ... February 13, 2020 , ... The ... is up 2.9% from the estimated value of $93.9 billion in 2010, according to ... market. , “Growth in this market is driven by an aging ...
Breaking Medicine Technology:
Cached News: