HOME >> MEDICINE >> NEWS
'Sharp' older brains are not the same as younger brains

Researchers working with rats have found the first solid evidence that still "sharp" older brains store and encode memories differently than younger brains.

This discovery is reported by a Johns Hopkins team in the issue of Nature Neuroscience released online Nov. 13. Should it prove to apply as well to human brains, it could lead eventually to the development of new preventive treatments and therapies based on what healthy older brains are doing, rather than on the less relevant, younger brain model, according to study co-author Michela Gallagher, chair of the Department of Psychological and Brain Sciences at Johns Hopkins' Zanvyl Krieger School of Arts and Sciences.

"We found that aged rats with preserved cognitive abilities are not biologically equivalent to young rats in some of the basic machinery that neurons use to encode and store information in the brain," said Gallagher, who collaborated with Alfredo Kirkwood and Sun Seek Min of Johns Hopkins' Krieger Mind/Brain Institute and Hey-Kyoung Lee, now of the University of Maryland College Park. Lee was a research associate at the Mind/Brain Institute when the research was done.

The Gallagher-Kirkwood team compared the brains of 6-month-old rats with those of 2-year-old (considered "aged") rodents that had performed in the "young" range on various learning tasks. The aged rats' brains also were compared with those of older rats which showed declines in their abilities to learn new things. The researchers were looking at a key set of nerve cell connections that store information by modifying the strength of chemical communications at their synapses. (Synapses are the tiny gaps between nerve cells, where chemicals released by one cell act upon another.) Synaptic communication is the way brains register and preserve information to form memories.

The team found that while the older rats with compromised cognition had brains that had lost the ability to adjust the force of tho
'"/>

Contact: Lisa DeNike
Lde@jhu.edu
443-287-9960
Johns Hopkins University
13-Nov-2005


Page: 1 2

Related medicine news :

1. Grandparents, older adults encouraged to seek help for a sleep disorder
2. Even older women at high risk have little interest in being tested for HIV, study finds
3. Osteoporosis screening and treatment may be cost-effective for selected older men
4. Antipsychotic drugs increase risk of death in older people with dementia
5. Antipsychotic drugs increase risk of death in older people with dementia
6. Predicting the quality of life for older adults
7. Major employers, physicians, stakeholders unite to revolutionize Americas healthcare system
8. No evidence older women generate new eggs
9. Higher calcium and vitamin D intakes positively associated with brain lesions in older men and women
10. Help the Aged funds the University of Nottingham to research pain affecting older people
11. Tai Chi boosts immunity to shingles virus in older adults, NIH-sponsored study reports

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/14/2018)... ... November 14, 2018 , ... “The Health Insurance Marketplace ... and continues through Dec. 15, 2018). Enrolling in the Marketplace can be daunting. ... to be an overwhelming process,” explained Bob Dial, Chief Compliance Officer, Preferred ...
(Date:11/13/2018)... ... 14, 2018 , ... REMS: Requirements, Regulation, and Enforcement:, Evolution ... 1:30 p.m. – 3:00 p.m. ET, http://www.fdanews.com/remsrre , ... tool. A constantly evolving enforcement tool. , In September the FDA added immediate-release ...
(Date:11/13/2018)... ... November 13, 2018 , ... Azzur ... today the opening of its newest laboratory located in Cary, NC. Seated in ... comprehensive services to top U.S. manufacturers and brings additional jobs to the Raleigh ...
(Date:11/13/2018)... SACRAMENTO, Calif. (PRWEB) , ... November 13, 2018 ... ... in its history, the insurance industry is working around the clock to help ... now is the safety of its customers,” said Katie Pettibone, vice president of ...
(Date:11/13/2018)... ... November 13, 2018 , ... Capillus was honored to ... that took place on November 4th at Lucien’s Manor in New Jersey. Each year ... By Your Side to provide courageous women battling cancer with a wig at no ...
Breaking Medicine News(10 mins):
(Date:11/13/2018)... (PRWEB) , ... November 13, 2018 , ... Society has ... posture while sitting. Unfortunately, regular chairs that maintain a 90-degree angle between the back ... time. It is impossible to achieve correct spinal positioning when sitting in a typical ...
(Date:11/13/2018)... NEW YORK (PRWEB) , ... November 13, 2018 ... ... the post-acute care industry, announced today that it has made available a new ... Citus Video Chat deepens the functionality of the Citus Health Platform adding another ...
(Date:11/13/2018)... DANVERS, Mass. (PRWEB) , ... November 13, 2018 , ... ... to receive a Life Science Industry Award for both Best Digital Advertising and Most ... life science leader at the 2018 Life Science Industry Awards Ceremony in San Diego ...
Breaking Medicine Technology:
Cached News: